Drug regulation articles within Scientific Reports

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• Article
  22 April 2024 | Open Access

  Hexahydrocannabinol (HHC) and Δ⁹-tetrahydrocannabinol (Δ⁹-THC) driven activation of cannabinoid receptor 1 results in biased intracellular signaling

  • Oleh Durydivka
  • , Petr Palivec
  •  & Martin Kuchar

• Article
  20 April 2024 | Open Access

  Factors associated with hematological adverse reactions of drugs authorized via the centralized procedure

  • Ivana Stević
  • , Slobodan M. Janković
  •  & Dragana Lakić

• Article
  26 March 2024 | Open Access

  Fully connected-convolutional (FC-CNN) neural network based on hyperspectral images for rapid identification of P. ginseng growth years

  • Xingfeng Chen
  • , Hejuan Du
  •  & Shu Liu

• Article
  23 March 2024 | Open Access

  Multidrug-resistant conjugative plasmid carrying mphA confers increased antimicrobial resistance in Shigella

  • Asaduzzaman Asad
  • , Israt Jahan
  •  & Zhahirul Islam

• Article
  01 March 2024 | Open Access

  A real-world analysis of FDA Adverse Event Reporting System (FAERS) events for liposomal and conventional doxorubicins

  • Huiling Su
  • , Jing Jia
  •  & Zhengjun Li

• Article
  24 February 2024 | Open Access

  Alcohol consumption as a socially contagious phenomenon in the Framingham Heart Study social network

  • Maarten W. J. van den Ende
  • , Han L. J. van der Maas
  •  & Mike H. Lees

• Article
  09 February 2024 | Open Access

  Analysis of US Food and Drug Administration new drug and biologic approvals, regulatory pathways, and review times, 1980–2022

  • Enrique Seoane-Vazquez
  • , Rosa Rodriguez-Monguio
  •  & John H. Powers III

• Article
  23 January 2024 | Open Access

  Effect of norepinephrine, vasopressin, and dopamine for survivals of the elderly with sepsis and pre-existing heart failure

  • Baohua Zhu
  • , Jie Jiang
  •  & Dandan Zhou

• Article
  27 December 2023 | Open Access

  Trajectory modeling of cannabis use over 30 years identifies five unique longitudinal patterns

  • Amy R. Mahar
  • , Michael P. Bancks
  •  & Gregory L. Kinney

• Article
  12 October 2023 | Open Access

  Scientific facts improve cannabis perception and public opinion: results from Sinaloa, México

  • Josué Camberos-Barraza
  • , Juan F. Osuna-Ramos
  •  & Alberto K. De la Herrán-Arita

• Article
  08 October 2023 | Open Access

  Knowledge, sex, and region associated with primary care providers prescribing adolescents HIV pre-exposure prophylaxis

  • Garrett Price
  • , Randolph D. Hubach
  •  & Christopher Owens

• Article
  27 September 2023 | Open Access

  A fixed 20:1 combination of cafedrine/theodrenaline increases cytosolic Ca²⁺ concentration in human tracheal epithelial cells via ryanodine receptor-mediated Ca²⁺ release

  • Götz Schmidt
  • , Gerrit Rienas
  •  & Michael Henrich

• Article
  25 September 2023 | Open Access

  Case analysis of long-term negative psychological responses to psychedelics

  • Rebecka Bremler
  • , Nancy Katati
  •  & Robin L. Carhart-Harris

• Article
  31 July 2023 | Open Access

  Multi-omic analyses of triptan-treated migraine attacks gives insight into molecular mechanisms

  • Lisette J. A. Kogelman
  • , Katrine Falkenberg
  •  & Thomas Folkmann Hansen

• Article
  03 February 2023 | Open Access

  Yoghurt as a deglutition aid for oral medication: effects on famotidine powder dissolution rate and pharmacokinetics

  • Yayoi Gotoh
  • , Yoshiyuki Tabata
  •  & Toshio Suzuki

• Article
  30 January 2023 | Open Access

  A comparative study of postmortem distribution and postmortem diffusion of tramadol in rabbits

  • Hongliang Su
  • , Lingxiao Wang
  •  & Keming Yun

• Article
  30 January 2023 | Open Access

  Diagnosis and treatment of intractable idiopathic orofacial pain with attention-deficit/hyperactivity disorder

  • Satoshi Kasahara
  • , Kaori Takahashi
  •  & Kanji Uchida

• Article
  14 January 2023 | Open Access

  Effect of date molasses on levetiracetam pharmacokinetics in healthy rats

  • Wael Abu Dayyih
  • , Raghad Layth
  •  & Saed M. Aldalaen

• Article
  31 October 2022 | Open Access

  Quality and safety investigation of commonly used topical cosmetic preparations

  • May Almukainzi
  • , Lubna Alotaibi
  •  & Areej M. El Mahdy

• Article
  07 October 2022 | Open Access

  The effect of short-term refrigeration on platelet responsiveness

  • Anna Kobsar
  • , Karina Koehnlechner
  •  & Juergen Koessler

• Article
  05 October 2022 | Open Access

  Influence of Huangqin Decoction on the immune function and fecal microbiome of chicks after experimental infection with Escherichia coli O78

  • Junyan Wang
  • , Rui Li
  •  & Xichun Zhang

• Article
  23 September 2022 | Open Access

  Silymarin reduces retinal microvascular damage in streptozotocin-induced diabetic rats

  • Rahman Karimi
  • , Ali Bakhshi
  •  & Seyed Morteza Naghib

• Article
  30 July 2022 | Open Access

  Surveillance for substandard and falsified medicines by local faith-based organizations in 13 low- and middle-income countries using the GPHF Minilab

  • Gesa Gnegel
  • , Christine Häfele-Abah
  •  & Lutz Heide

• Article
  22 July 2022 | Open Access

  Discrimination of Curculigo orchioides Rhizoma and Curculigo glabrescens Rhizoma using stable isotope and mineral element analyses coupled with chemometrics

  • Yushi Liu
  • , Yiping Guo
  •  & Li Guo

• Article
  30 June 2022 | Open Access

  Comparative transcriptome analysis reveals the resistance regulation mechanism and fungicidal activity of the fungicide phenamacril in Fusarium oxysporum

  • Zhitian Zheng
  • , Huaqi Liu
  •  & Feng Zhang

• Article
  22 June 2022 | Open Access

  Retrospective evaluation of early thrombosis in transjugular intrahepatic portosystemic polytetrafluoroethylene-coated shunts under 2-day postinterventional heparinization

  • Holger Goessmann
  • , Verna Schuffenhauer
  •  & Niklas Verloh

• Article
  20 June 2022 | Open Access

  Automated gathering of real-world data from online patient forums can complement pharmacovigilance for rare cancers

  • Anne Dirkson
  • , Suzan Verberne
  •  & Hans Gelderblom

• Article
  11 May 2022 | Open Access

  Simple, fast and reliable CE method for simultaneous determination of ciprofloxacin and ofloxacin in human urine

  • Izabella Kośka
  • , Krystian Purgat
  •  & Paweł Kubalczyk

• Article
  03 May 2022 | Open Access

  A network approach to relationships between cannabis use characteristics and psychopathology in the general population

  • Linda T. Betz
  • , Nora Penzel
  •  & Joseph Kambeitz

• Article
  03 May 2022 | Open Access

  Symptom-based pharmacotherapy for neuropathic pain related to spinal disorders: results from a patient-based assessment

  • Hideaki Nakajima
  • , Shuji Watanabe
  •  & Akihiko Matsumine

• Article
  13 April 2022 | Open Access

  Algorithmic multiscale analysis for the FcRn mediated regulation of antibody PK in human

  • Dimitris G. Patsatzis
  • , Shengjia Wu
  •  & Dimitris A. Goussis

• Article
  17 March 2022 | Open Access

  Antifungals influence the immune-related transcriptomic landscape of human monocytes after Aspergillus fumigatus infection

  • Benoît Henry
  • , William Klement
  •  & Shahid Husain

• Article
  31 December 2021 | Open Access

  Hypoxia driven opioid targeted automated device for overdose rescue

  • Mohammad S. Imtiaz
  • , Charles V. Bandoian
  •  & Thomas J. Santoro

• Article
  26 November 2021 | Open Access

  Curcumin derivative ST09 modulates the miR-199a-5p/DDR1 axis and regulates proliferation and migration in ovarian cancer cells

  • Febina Ravindran
  • , Jinsha Koroth
  •  & Bibha Choudhary

• Article
  23 November 2021 | Open Access

  A comprehensive breath test that confirms recent use of inhaled cannabis within the impairment window

  • Michael W. DeGregorio
  • , Gregory T. Wurz
  •  & Chiao-Jung Kao

• Article
  11 November 2021 | Open Access

  Pharmacological effects of novel microvesicles of basil, on blood glucose and the lipid profile: a preclinical study

  • Branislava Teofilovic
  • , Svetlana Golocorbin-Kon
  •  & Momir Mikov

• Article
  21 October 2021 | Open Access

  Impact of the day of the week on the discontinuation of broad-spectrum antibiotic prescriptions; a multi-centered observational study

  • Hiroyuki Honda
  • , Hideharu Hagiya
  •  & Fumio Otsuka

• Article
  11 October 2021 | Open Access

  High alert drugs screening using gradient boosting classifier

  • Pakpoom Wongyikul
  • , Nuttamon Thongyot
  •  & Piyapong Khumrin

• Article
  29 September 2021 | Open Access

  TYROBP, TLR4 and ITGAM regulated macrophages polarization and immune checkpoints expression in osteosarcoma

  • Tuo Liang
  • , Jiarui Chen
  •  & Xinli Zhan

• Article
  30 July 2021 | Open Access

  Tailoring the effect of antithrombin-targeting therapy in haemophilia A using in silico thrombin generation

  • Romy M. W. de Laat-Kremers
  • , Marisa Ninivaggi
  •  & Bas de Laat

• Article
  06 July 2021 | Open Access

  Apixaban concentration variability and relation to clinical outcomes in real-life patients with atrial fibrillation

  • Alenka Mavri
  • , Nina Vene
  •  & Jovan Antovic

• Article
  03 June 2021 | Open Access

  The impact of acute diarrhea on the coagulation status of patients with vitamin K antagonists

  • Johannes Schweinfurth
  • , Alexander Bauer
  •  & Timm Henning Westhoff

• Article
  04 May 2021 | Open Access

  Management of ongoing direct anticoagulant treatment in patients with hip fracture

  • Carlo Rostagno
  • , Alessandro Cartei
  •  & Domenico Prisco

• Article
  23 April 2021 | Open Access

  Safety of traditional Chinese medicine injection based on spontaneous reporting system from 2014 to 2019 in Hubei Province, China

  • Rui Huang
  • , Yuanxuan Cai
  •  & Shangfeng Tang

• Article
  18 March 2021 | Open Access

  Performance of preclinical models in predicting drug-induced liver injury in humans: a systematic review

  • Hubert Dirven
  • , Gunn E. Vist
  •  & Katya Tsaioun

• Article
  16 March 2021 | Open Access

  Thermolabile drug storage in an ambulatory setting

  • Fernando do Pazo-Oubiña
  • , Bartomeu Alorda-Ladaria
  •  & Olga Delgado-Sanchez

• Article
  26 February 2021 | Open Access

  Influence of bound dodecanoic acid on the reconstitution of albumin nanoparticles from a lyophilized state

  • Christian C. E. Luebbert
  • , Rola Mansa
  •  & Michael J. W. Johnston

• Article
  12 February 2021 | Open Access

  Arsenic hexoxide has differential effects on cell proliferation and genome-wide gene expression in human primary mammary epithelial and MCF7 cells

  • Donguk Kim
  • , Na Yeon Park
  •  & Heeyoun Bunch

• Article
  13 January 2021 | Open Access

  Mechanism of action and potential applications of selective inhibition of microsomal prostaglandin E synthase-1-mediated PGE₂ biosynthesis by sonlicromanol’s metabolite KH176m

  • X. Jiang
  • , H. Renkema
  •  & J. Beyrath

• Article
  12 January 2021 | Open Access

  Controlled release evaluation of paracetamol loaded amine functionalized mesoporous silica KCC1 compared to microcrystalline cellulose based tablets

  • Marieh Pishnamazi
  • , Hamid Hafizi
  •  & Gavin M. Walker