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| Open AccessTranscriptional factor ATF3 promotes liver fibrosis via activating hepatic stellate cells
- Zhemin Shi
- , Kun Zhang
- & Wei Hong
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Article
| Open AccessDistinct photo-oxidation-induced cell death pathways lead to selective killing of human breast cancer cells
- Ancély F. Dos Santos
- , Alex Inague
- & Leticia Labriola
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Comment
| Open Access4EBP1/2 are active under standard cell culture conditions to regulate the translation of specific mRNAs
- Khawla Alasad
- , Kai Voeltzke
- & Barak Rotblat
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Article
| Open AccessMCL1 binds and negatively regulates the transcriptional function of tumor suppressor p73
- Hayley Widden
- , Aneta Kaczmarczyk
- & William J. Placzek
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Article
| Open AccessMicroRNA-200b/c-3p regulate epithelial plasticity and inhibit cutaneous wound healing by modulating TGF-β-mediated RAC1 signaling
- Huiyi Tang
- , Xueer Wang
- & Lin Zhang
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Article
| Open AccessExcessive phospholipid peroxidation distinguishes ferroptosis from other cell death modes including pyroptosis
- Bartosz Wiernicki
- , Hanne Dubois
- & Tom Vanden Berghe
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Article
| Open AccessInactivation of ribosomal protein S27-like impairs DNA interstrand cross-link repair by destabilization of FANCD2 and FANCI
- Siyuan Sun
- , Hengqian He
- & Xiufang Xiong
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Article
| Open AccessRequirement for Serine-384 in Caspase-2 processing and activity
- Alexey V. Zamaraev
- , Pavel I. Volik
- & Gelina S. Kopeina
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Article
| Open AccessOxygen glucose deprivation/re-oxygenation-induced neuronal cell death is associated with Lnc-D63785 m6A methylation and miR-422a accumulation
- Shu Xu
- , Ya Li
- & Xiao-zhong Zhou
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Article
| Open AccessMutual regulation between OGT and XIAP to control colon cancer cell growth and invasion
- Hyeon Gyu Seo
- , Han Byeol Kim
- & Jin Won Cho
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Article
| Open AccessUSP29 enhances chemotherapy-induced stemness in non-small cell lung cancer via stabilizing Snail1 in response to oxidative stress
- Yueguang Wu
- , Yingqiu Zhang
- & Han Liu
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Article
| Open AccessFlavin dependency undermines proteome stability, lipid metabolism and cellular proliferation during vitamin B2 deficiency
- Adrían Martínez-Limón
- , Giulia Calloni
- & R. Martin Vabulas
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Article
| Open AccessMembrane-tethering of cytochrome c accelerates regulated cell death in yeast
- Alexandra Toth
- , Andreas Aufschnaiter
- & Martin Ott
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Article
| Open AccessCell density-dependent proteolysis by HtrA1 induces translocation of zyxin to the nucleus and increased cell survival
- Fabio Sabino
- , Elizabeta Madzharova
- & Ulrich auf dem Keller
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Article
| Open AccessShedding of cancer susceptibility candidate 4 by the convertases PC7/furin unravels a novel secretory protein implicated in cancer progression
- Stéphanie Duval
- , Afnan Abu-Thuraia
- & Nabil G. Seidah
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Article
| Open AccessComputational repositioning of dimethyl fumarate for treating alcoholic liver disease
- Ye Zhang
- , Shuang Zhao
- & Ting Liu
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Article
| Open AccessA novel N6-methyladenosine (m6A)-dependent fate decision for the lncRNA THOR
- Hongmei Liu
- , Yuxin Xu
- & Zhanjun Li
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Article
| Open AccessVenetoclax causes metabolic reprogramming independent of BCL-2 inhibition
- Alba Roca-Portoles
- , Giovanny Rodriguez-Blanco
- & Stephen W. G. Tait
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Article
| Open AccessCircularRNA-9119 protects hepatocellular carcinoma cells from apoptosis by intercepting miR-26a/JAK1/STAT3 signaling
- Lixue Yang
- , Hui Xue
- & Ruiliang Ge
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Article
| Open AccessActivating PIK3CA mutation promotes adipogenesis of adipose-derived stem cells in macrodactyly via up-regulation of E2F1
- Bin Sun
- , Yongkang Jiang
- & Bin Wang
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Article
| Open AccessGADD45α drives brown adipose tissue formation through upregulating PPARγ in mice
- Wenjing You
- , Ziye Xu
- & Tizhong Shan
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Article
| Open AccessAltered mitochondrial dynamics and function in APOE4-expressing astrocytes
- Eran Schmukler
- , Shira Solomon
- & Ronit Pinkas-Kramarski
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Article
| Open AccessLINC00266-1/miR-548c-3p/SMAD2 feedback loop stimulates the development of osteosarcoma
- Shengnai Zheng
- , Li Wan
- & Lei Yang
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Article
| Open AccessCircRNA TADA2A relieves idiopathic pulmonary fibrosis by inhibiting proliferation and activation of fibroblasts
- Juan Li
- , Ping Li
- & Wei Zhao
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Article
| Open AccessThe integrated stress response induces R-loops and hinders replication fork progression
- Josephine Ann Mun Yee Choo
- , Denise Schlösser
- & Matthias Dobbelstein
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Article
| Open AccessHOTAIRM1 regulates neuronal differentiation by modulating NEUROGENIN 2 and the downstream neurogenic cascade
- Jessica Rea
- , Valentina Menci
- & Elisa Caffarelli
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Article
| Open AccessLong intergenic non-protein-coding RNA 01446 facilitates the proliferation and metastasis of gastric cancer cells through interacting with the histone lysine-specific demethylase LSD1
- Yifan Lian
- , Changsheng Yan
- & Hongzhi Xu
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Review Article
| Open AccessAutophagy as a modulator of cell death machinery
- Masayuki Noguchi
- , Noriyuki Hirata
- & John A. Chiorini
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Article
| Open AccessChondroitin polymerizing factor (CHPF) promotes development of malignant melanoma through regulation of CDK1
- Wei Sun
- , Fang Zhao
- & Yong Chen
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Article
| Open AccessBrd4 inhibition ameliorates Pyocyanin-mediated macrophage dysfunction via transcriptional repression of reactive oxygen and nitrogen free radical pathways
- Feimei Zhu
- , Feng Xiong
- & Yi Wang
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Article
| Open AccessMitochondrial dysfunction generates aggregates that resist lysosomal degradation in human breast cancer cells
- Thomas G. Biel
- , Baikuntha Aryal
- & V. Ashutosh Rao
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Article
| Open AccessHexokinase 2 is dispensable for photoreceptor development but is required for survival during aging and outer retinal stress
- Eric Weh
- , Zuzanna Lutrzykowska
- & Cagri G. Besirli
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Article
| Open AccessFine tuning of the unfolded protein response by ISRIB improves neuronal survival in a model of amyotrophic lateral sclerosis
- Ricardo Bugallo
- , Elías Marlin
- & Tomás Aragón
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Article
| Open AccessHUWE1-dependent DNA-PKcs neddylation modulates its autophosphorylation in DNA damage response
- Zongpei Guo
- , Shaozheng Wang
- & Teng Ma
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Article
| Open AccessAPN-mediated phosphorylation of BCKDK promotes hepatocellular carcinoma metastasis and proliferation via the ERK signaling pathway
- Mengying Zhai
- , Zixia Yang
- & Zheng Fu
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Article
| Open AccessTanshinone IIA inhibits oral squamous cell carcinoma via reducing Akt-c-Myc signaling-mediated aerobic glycolysis
- Ming Li
- , Feng Gao
- & Wei Li
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Article
| Open AccessPKCθ-JunB axis via upregulation of VEGFR3 expression mediates hypoxia-induced pathological retinal neovascularization
- Raj Kumar
- , Arul M. Mani
- & Gadiparthi N. Rao
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Article
| Open AccessThe USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53
- Chen Hu
- , Mu Zhang
- & Xiaohong Mary Zhang
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Article
| Open AccessFormate induces a metabolic switch in nucleotide and energy metabolism
- Kristell Oizel
- , Jacqueline Tait-Mulder
- & Alexei Vazquez
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Article
| Open AccessApoptosome-dependent myotube formation involves activation of caspase-3 in differentiating myoblasts
- Mahshid H. Dehkordi
- , Amin Tashakor
- & Howard O. Fearnhead
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Article
| Open AccessKeratinocyte transglutaminase 2 promotes CCR6+ γδT-cell recruitment by upregulating CCL20 in psoriatic inflammation
- Ji-Woong Shin
- , Mee-ae Kwon
- & In-Gyu Kim
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Article
| Open AccessRNA methyltransferase NSUN2 promotes gastric cancer cell proliferation by repressing p57Kip2 by an m5C-dependent manner
- Lin Mei
- , Cheng Shen
- & Ji-Fu Wei
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Article
| Open AccessRobust autoactivation for apoptosis by BAK but not BAX highlights BAK as an important therapeutic target
- Sweta Iyer
- , Rachel T. Uren
- & Ruth M. Kluck
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Article
| Open AccessCirc_0002770, acting as a competitive endogenous RNA, promotes proliferation and invasion by targeting miR-331-3p in melanoma
- Peng Qian
- , Liu Linbo
- & Pei Hui
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Article
| Open AccessEnhanced fatty acid oxidation provides glioblastoma cells metabolic plasticity to accommodate to its dynamic nutrient microenvironment
- Shiva Kant
- , Pravin Kesarwani
- & Prakash Chinnaiyan
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Article
| Open AccessThe cellular prion protein is a stress protein secreted by renal tubular cells and a urinary marker of kidney injury
- Yohan Bignon
- , Virginie Poindessous
- & Nicolas Pallet
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Article
| Open AccessHistone demethylase JMJD1A promotes expression of DNA repair factors and radio-resistance of prostate cancer cells
- Lingling Fan
- , Songhui Xu
- & Jianfei Qi
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Article
| Open AccessElevated intracellular copper contributes a unique role to kidney fibrosis by lysyl oxidase mediated matrix crosslinking
- Yang-yang Niu
- , Ying-ying Zhang
- & Chen Yu
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Article
| Open AccessTNF-Receptor-1 inhibition reduces liver steatosis, hepatocellular injury and fibrosis in NAFLD mice
- Franziska Wandrer
- , Stephanie Liebig
- & Heike Bantel
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