Featured
-
-
Review Article
| Open AccessDouble-edge sword roles of iron in driving energy production versus instigating ferroptosis
- Shuping Zhang
- , Wei Xin
- & Sijin Liu
-
Article
| Open AccessTMEM165 a new player in proteoglycan synthesis: loss of TMEM165 impairs elongation of chondroitin- and heparan-sulfate glycosaminoglycan chains of proteoglycans and triggers early chondrocyte differentiation and hypertrophy
- Sajida Khan
- , Malak Sbeity
- & Mohamed Ouzzine
-
Article
| Open AccessCPEB3 deficiency in mice affect ovarian follicle development and causes premature ovarian insufficiency
- Fang E.
- , He Zhang
- & Xu Gao
-
Article
| Open AccessAlpha-(1,6)-fucosyltransferase (FUT8) affects the survival strategy of osteosarcoma by remodeling TNF/NF-κB2 signaling
- Shanyi Lin
- , Lenian Zhou
- & Shumin Zhou
-
Article
| Open AccessP2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells
- Anna Pegoraro
- , Elena De Marchi
- & Elena Adinolfi
-
Article
| Open AccessCircESRP1 inhibits clear cell renal cell carcinoma progression through the CTCF-mediated positive feedback loop
- Lin-Jing Gong
- , Xin-Yuan Wang
- & Wen-Yu Gu
-
Article
| Open AccessAge-related neurodegeneration and cognitive impairments of NRMT1 knockout mice are preceded by misregulation of RB and abnormal neural stem cell development
- James P. Catlin
- , Leandro N. Marziali
- & Christine E. Schaner Tooley
-
Article
| Open AccessSmooth muscle 22 alpha protein inhibits VSMC foam cell formation by supporting normal LXRα signaling, ameliorating atherosclerosis
- Dan-Dan Zhang
- , Yu Song
- & Mei Han
-
Article
| Open AccessPhosphoglycerate kinase 1 silencing by a novel microRNA microRNA-4523 protects human osteoblasts from dexamethasone through activation of Nrf2 signaling cascade
- Jin-qian Liang
- , Zhen-tao Zhou
- & Ming-sheng Tan
-
Article
| Open AccessDownregulation of PHLPP induced by endoplasmic reticulum stress promotes eIF2α phosphorylation and chemoresistance in colon cancer
- Bianqin Guo
- , Xiaopeng Xiong
- & Tianyan Gao
-
Article
| Open AccessTDAG51 induces renal interstitial fibrosis through modulation of TGF-β receptor 1 in chronic kidney disease
- Rachel E. Carlisle
- , Zahraa Mohammed-Ali
- & Jeffrey G. Dickhout
-
Article
| Open AccessSulforaphane downregulated fatty acid synthase and inhibited microtubule-mediated mitophagy leading to apoptosis
- Yuting Yan
- , Yan Zhou
- & Wei Wu
-
Article
| Open AccessInhibition of nuclear receptor RORα attenuates cartilage damage in osteoarthritis by modulating IL-6/STAT3 pathway
- Tongzhou Liang
- , Taiqiu Chen
- & Dongsheng Huang
-
Article
| Open AccessUSP7 facilitates SMAD3 autoregulation to repress cancer progression in p53-deficient lung cancer
- Yu-Ting Huang
- , An-Chieh Cheng
- & Wei-Yi Chen
-
Article
| Open AccessFear-of-intimacy-mediated zinc transport controls fat body cell dissociation through modulating Mmp activity in Drosophila
- Tian Wei
- , Xiaowen Ji
- & Guiran Xiao
-
Article
| Open AccessEndotoxin stabilizes protein arginine methyltransferase 4 (PRMT4) protein triggering death of lung epithelia
- Yandong Lai
- , Xiuying Li
- & Chunbin Zou
-
Article
| Open AccessCasein Kinase 2 dependent phosphorylation of eIF4B regulates BACE1 expression in Alzheimer’s disease
- Barbara Bettegazzi
- , Laura Sebastian Monasor
- & Daniele Zacchetti
-
Article
| Open AccessTissue-specific expression of p73 and p63 isoforms in human tissues
- Clayton B. Marshall
- , J. Scott Beeler
- & Jennifer A. Pietenpol
-
Review Article
| Open AccessThe critical roles of histone deacetylase 3 in the pathogenesis of solid organ injury
- Li Ning
- , Xiong Rui
- & Geng Qing
-
Article
| Open AccessThe regulation of ferroptosis by MESH1 through the activation of the integrative stress response
- Chao-Chieh Lin
- , Chien-Kuang Cornelia Ding
- & Jen-Tsan Chi
-
Article
| Open AccessAntioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor
- Tom Delanghe
- , Jon Huyghe
- & Mathieu J. M. Bertrand
-
Article
| Open AccessInduced TRIM21 ISGylation by IFN-β enhances p62 ubiquitination to prevent its autophagosome targeting
- Jie Jin
- , Xianbin Meng
- & Haiteng Deng
-
Article
| Open AccessMYC-targeted WDR4 promotes proliferation, metastasis, and sorafenib resistance by inducing CCNB1 translation in hepatocellular carcinoma
- Peng Xia
- , Hao Zhang
- & Yufeng Yuan
-
Article
| Open Accessc-FLIP regulates autophagy by interacting with Beclin-1 and influencing its stability
- Luana Tomaipitinca
- , Simonetta Petrungaro
- & Claudia Giampietri
-
Article
| Open AccessEndoplasmic reticulum−mitochondria coupling increases during doxycycline-induced mitochondrial stress in HeLa cells
- Camila Lopez-Crisosto
- , Alexis Díaz-Vegas
- & Sergio Lavandero
-
Article
| Open AccessParp mutations protect from mitochondrial toxicity in Alzheimer’s disease
- Yizhou Yu
- , Giorgio Fedele
- & L. Miguel Martins
-
Article
| Open AccessFURIN and placental syncytialisation: a cautionary tale
- Saije K. Morosin
- , Sarah J. Delforce
- & Kirsty G. Pringle
-
Article
| Open AccessClobetasol promotes neuromuscular plasticity in mice after motoneuronal loss via sonic hedgehog signaling, immunomodulation and metabolic rebalancing
- Nunzio Vicario
- , Federica M. Spitale
- & Rosario Gulino
-
Article
| Open AccessK63-linked ubiquitination of DYRK1A by TRAF2 alleviates Sprouty 2-mediated degradation of EGFR
- Pengshan Zhang
- , Zhe Zhang
- & Man Mohan
-
Article
| Open AccessThe RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase
- Alexandra Daks
- , Alexey Petukhov
- & Nickolai Barlev
-
Article
| Open AccessCD36 promotes NLRP3 inflammasome activation via the mtROS pathway in renal tubular epithelial cells of diabetic kidneys
- Yanjuan Hou
- , Qian Wang
- & Lihua Wang
-
Article
| Open AccessEGFR phosphorylates HDAC1 to regulate its expression and anti-apoptotic function
- Sonali Bahl
- , Hongbo Ling
- & Edward Seto
-
Article
| Open AccessSuppression of USP7 induces BCR-ABL degradation and chronic myelogenous leukemia cell apoptosis
- Shuoyi Jiang
- , Xiaoge Wang
- & Xinliang Mao
-
Article
| Open AccessMitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis
- Peina Wang
- , Yanmei Cui
- & Yan-Zhong Chang
-
Article
| Open AccessGIPC2 is an endocrine-specific tumor suppressor gene for both sporadic and hereditary tumors of RET- and SDHB-, but not VHL-associated clusters of pheochromocytoma/paraganglioma
- Yeqing Dong
- , Yongsheng Huang
- & Zhi Zheng
-
Article
| Open AccessCellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells
- Jingru Huangfu
- , Caili Hao
- & Xingjun Fan
-
Article
| Open AccessMembrane lymphotoxin-α2β is a novel tumor necrosis factor (TNF) receptor 2 (TNFR2) agonist
- Kirstin Kucka
- , Isabell Lang
- & Harald Wajant
-
Article
| Open AccessSENP1-mediated deSUMOylation of JAK2 regulates its kinase activity and platinum drug resistance
- Jing Li
- , Ruiqin Wu
- & Wenge Zhu
-
Article
| Open AccessAutophagy-dependent survival is controlled with a unique regulatory network upon various cellular stress events
- Orsolya Kapuy
- , Marianna Holczer
- & Tamás Korcsmáros
-
Article
| Open AccessS-adenosylmethionine upregulates the angiotensin receptor-binding protein ATRAP via the methylation of HuR in NAFLD
- Tao Guo
- , Zhe Dai
- & Zhen Li
-
Article
| Open AccessThe Sumo proteome of proliferating and neuronal-differentiating cells reveals Utf1 among key Sumo targets involved in neurogenesis
- Juan F. Correa-Vázquez
- , Francisco Juárez-Vicente
- & Mario García-Domínguez
-
Article
| Open AccessAn interaction between PRRT2 and Na+/K+ ATPase contributes to the control of neuronal excitability
- Bruno Sterlini
- , Alessandra Romei
- & Anna Corradi
-
Article
| Open AccessSplicing factor USP39 promotes ovarian cancer malignancy through maintaining efficient splicing of oncogenic HMGA2
- Shourong Wang
- , Zixiang Wang
- & Zhaojian Liu
-
Article
| Open AccessAberrant Gcm1 expression mediates Wnt/β-catenin pathway activation in folate deficiency involved in neural tube defects
- Jianting Li
- , Qiu Xie
- & Jun Xie
-
Article
| Open AccessCircular RNA circ_103820 suppresses lung cancer tumorigenesis by sponging miR-200b-3p to release LATS2 and SOCS6
- Yongbin Chi
- , Wenlong Zheng
- & Mingming Jin
-
Article
| Open AccessWithaferin A alleviates fulminant hepatitis by targeting macrophage and NLRP3
- Yangliu Xia
- , Ping Wang
- & Tingting Yan
-
Article
| Open AccessP2X7 receptor signaling promotes inflammation in renal parenchymal cells suffering from ischemia-reperfusion injury
- Yingying Qian
- , Cheng Qian
- & Leyi Gu
-
Article
| Open AccessGalectin-1 accelerates high-fat diet-induced obesity by activation of peroxisome proliferator-activated receptor gamma (PPARγ) in mice
- Jung-Hwan Baek
- , Da-Hyun Kim
- & Kyung-Hee Chun
-
Article
| Open AccessNeutral lipids as early biomarkers of cellular fate: the case of α-synuclein overexpression
- Natalia P. Alza
- , Melisa A. Conde
- & Gabriela A. Salvador
Browse broader subjects
Browse narrower subjects
- Biocatalysis
- Biogeochemistry
- Bioinorganic chemistry
- Biophysical chemistry
- Carbohydrates
- Chemical modification
- Cytokines
- DNA
- Enzyme mechanisms
- Enzymes
- Glycobiology
- Glycomics
- Histocytochemistry
- Hormones
- Immunochemistry
- Ion channels
- Isoenzymes
- Kinases
- Lipidomics
- Lipids
- Metabolomics
- Metals
- Neurochemistry
- Peptides
- Prions
- Proteases
- Protein folding
- Proteins
- Proteolysis
- Proteomics
- RNA
- Structural biology