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The latest articles published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).

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Continuing Medical Education

Saturation biopsies for prostate cancer: current uses and future prospects

Nicolas B. Delongchamps & Gabriel P. Haas

Published online: 10 November 2009 | doi:10.1038/nrurol.2009.213

There is a trend towards increasing the number of cores sampled during ultrasound-guided prostate biopsy in an attempt to increase the likelihood of detecting malignancy. Here, the authors' analysis of current data indicates that this 'saturation' approach is best used to improve histological characterization of cancer, and for monitoring of men with a rising PSA level despite previous negative biopsy.

Intravesical oxybutynin in the pediatric neurogenic bladder

John Lazarus

Published online: 10 November 2009 | doi:10.1038/nrurol.2009.214

Topical treatment of neuropathic bladder has been suggested as a viable alternative to oral anticholinergic therapy in children, offering greater efficacy and reduced side effects. Lazarus reviews the current status of intravesical oxybutynin use, warning that although it has proven effective in some studies, there remains a low level of evidence.

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Until print versions of AOP papers are published, they should be cited in the style "Nature Reviews Urology AOP, published online day month year; doi:10.1038/nrurolXXX". Once the print version (identical to the AOP) is published, it should be cited as follows: "Nature Reviews Urology volume number, page range (year); doi:10.1038/nrurolXXX".

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