Butterfly on a background of microbes

The gut microbiome in systemic lupus erythematosus: lessons from rheumatic fever

  • Gregg J. Silverman
  • Doua F. Azzouz
  • Abhimanyu Amarnani
Review Article

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    Keep up to date with changes to the conference calendar this year and find out which meetings will be attended by the editors of Nature Reviews Rheumatology.

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  • New research has identified apolipoprotein E expressed by fibroblasts and macrophages in the infrapatellar fat pad and synovium as a pathogenetic mediator and potential therapeutic target in knee osteoarthritis.

    • Robert Phillips
    Research Highlight
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    • Sarah Onuora
    Research Highlight
  • Age-related B cells (ABCs) have pathogenic roles in autoimmune diseases. Research has now identified ZEB2 as the transcription factor that mediates differentiation into ABCs.

    • Robert Phillips
    Research Highlight
  • A meta-analysis of data from six genome-wide association study cohorts implicates several signalling pathways, including Hedgehog and Notch signalling, in Dupuytren disease.

    • Sarah Onuora
    Research Highlight
25 years of biologic therapy

25 years of biologic therapy

Biologic therapies with various modes of action have been introduced into the field of rheumatology over the past 25 years, and have revolutionized the treatment and outcomes in many rheumatic diseases. This collection from Nature Reviews Rheumatology brings together articles on biologic therapy in rheumatology, including the latest Reviews and Opinion pieces, as well as popular content from our archives.
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