Jennie Vallis

The effects of oxytocin on eating behaviour and metabolism in humans

This Review discusses the data that link oxytocin to eating behaviour and metabolism in humans and considers how the pathways involving oxytocin can be targeted in the treatment of metabolic diseases.

Latest Reviews

  • Review |

    The hypothalamus is the main integrator of endocrine regulation. Glia–neuron interactions contribute to physiological processes such as puberty, the maintenance of bodily homeostasis and ageing. Here, Vincent Prevot and Jerome Clasadonte discuss glia–neuron interactions in the control of hypothalamic neuroendocrine function.

    • Jerome Clasadonte
    •  & Vincent Prevot
  • Review |

    Targeting thermogenesis in brown fat and skeletal muscle to expend energy and reduce fat mass is a promising therapeutic strategy for treating obesity and related metabolic diseases. Here, Betz and Enerbäck discuss the different molecular pathways regulating thermogenesis in these organs and discuss how they can be therapeutically exploited.

    • Matthias J. Betz
    •  & Sven Enerbäck
  • Review |

    Populations of African descent are at the forefront of the worldwide epidemic of type 2 diabetes mellitus (T2DM). Here, Anne Sumner and colleagues discuss issues related to the diagnosis and prevention of T2DM in these populations, including screening test efficacy, prevention strategies and the relative paucity of genomic data.

    • Jean N. Utumatwishima
    • , Stephanie T. Chung
    • , Amy R. Bentley
    • , Margaret Udahogora
    •  & Anne E. Sumner
  • Review |

    As not all individuals with obesity respond to lifestyle modification, pharmacotherapy has a key role in tackling the obesity epidemic. Here, Gitanjali Srivastava and Caroline Apovian review the six currently available FDA-approved anti-obesity drugs in terms of safety, efficacy and clinical utility.

    • Gitanjali Srivastava
    •  & Caroline M. Apovian
  • Review |

    Angiopoietin-like 3 (ANGPTL3) has emerged as an important regulator of plasma lipoprotein levels by its inhibition of the enzyme lipoprotein lipase. Here, Sander Kersten provides an overview of the role of ANGPTL3 in lipoprotein metabolism and discusses why it holds considerable promise as a target for atherosclerosis.

    • Sander Kersten
  • Review |

    In this Review, Elizabeth Lawson discusses the data that link oxytocin to eating behaviour and metabolism in humans. Although further investigation is required, Lawson suggests that the pathways involving oxytocin can be targeted in the treatment of metabolic diseases such as obesity and diabetes mellitus.

    • Elizabeth A. Lawson

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Endocrine disruption

Macmillan Publishers

Endocrine disruption

A collection of articles from Nature Reviews Endocrinology on the biological effects of endocrine-disrupting chemicals and implications for human health.

David Holmes

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