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Original articles
Xiao, S. et al. Lac-Phe mediates the effects of metformin on food intake and body weight. Nat. Metab. https://doi.org/10.1038/s42255-024-00999-9 (2024)
Scott, B. et al. Metformin and feeding increase levels of the appetite-suppressing metabolite Lac-Phe in humans. Nat. Metab. https://doi.org/10.1038/s42255-024-01018-7 (2024)
Related article
Foretz, M. et al. Metformin: update on mechanisms of action and repurposing potential. Nat. Rev. Endocrinol 19, 460–476 (2023)
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Starling, S. Metformin acts through appetite-suppressing metabolite: Lac-Phe. Nat Rev Endocrinol (2024). https://doi.org/10.1038/s41574-024-00986-w
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DOI: https://doi.org/10.1038/s41574-024-00986-w