Caio Bracey

Proteostasis in cardiac health and disease

Latest Reviews

  • Review |

    In the past 2 decades, an increasing prevalence of risk factors for cardiovascular disease, such as obesity, physical inactivity, and diabetes mellitus, has been observed among young adults (aged 18–45 years) living in developed countries. In their Review, Andersson and Vasan discuss the evolving risk factor burden and available epidemiological data on cardiovascular disease in young adults.

    • Charlotte Andersson
    •  & Ramachandran S. Vasan
  • Review |

    Increased arterial stiffness influences pulse pressure, wave reflections, kidney function, and cardiovascular risk. In this Review, Safar describes the importance of arterial stiffness in the diagnosis and management of hypertension, using historical perspectives to emphasize the need for new treatment approaches in patients with essential hypertension.

    • Michel E. Safar
  • Review |

    Cardiovascular mortality among the almost 600 million people living in the Eastern Mediterranean region (EMR) has been proposed to increase more dramatically in the next decade than in any other region except Africa. Turk-Adawi and colleagues summarize the available data on cardiovascular disease burden, risk factors, and treatment modalities for the EMR population.

    • Karam Turk-Adawi
    • , Nizal Sarrafzadegan
    • , Ibtihal Fadhil
    • , Kathryn Taubert
    • , Masoumeh Sadeghi
    • , Nanette K. Wenger
    • , Nigel S. Tan
    •  & Sherry L. Grace
  • Review |

    This Review summarizes the latest findings on heart reverse remodelling, which demonstrate that despite apparent normalization of function, the molecular changes associated with heart failure persist in the reverse-remodelled heart. This myocardial remission is distinct from true recovery, in which both function and molecular makeup are normalized. These findings have implications for developing therapies to repair the failing heart.

    • Gene H. Kim
    • , Nir Uriel
    •  & Daniel Burkhoff
  • Review |

    Over the past decade, marijuana has been legalized for medicinal purposes or recreational use in many countries, and the potency of marijuana and synthetic cannabinoids has substantially increased. In this Review, Pacher and colleagues summarize the role of the endocannabinoid system in cardiovascular health and disease, and critically discuss the beneficial and detrimental cardiovascular effects of marijuana and synthetic cannabinoid use.

    • Pal Pacher
    • , Sabine Steffens
    • , György Haskó
    • , Thomas H. Schindler
    •  & George Kunos
  • Consensus Statement | | open

    A range of drugs is available for symptomatic angina, but the optimal choice or combination of therapies is often uncertain, and contemporary guidelines do not necessarily provide definite recommendations. In this Consensus Statement, Ferrari and colleagues propose an individualized approach to angina treatment, which takes into consideration the patient, their comorbidities, and the underlying mechanism of disease.

    • Roberto Ferrari
    • , Paolo G. Camici
    • , Filippo Crea
    • , Nicolas Danchin
    • , Kim Fox
    • , Aldo P. Maggioni
    • , Athanasios J. Manolis
    • , Mario Marzilli
    • , Giuseppe M. C. Rosano
    •  & José L. Lopez-Sendon

News & Comment


Immune system and cardiovascular disease

Immune system and cardiovascular disease

A collection of articles from Nature Reviews Cardiology on the role of the immune system in the pathophysiology of cardiovascular diseases

Irene Fernandez Ruiz

Natureevents Directory