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Protein glycosylation in cardiovascular health and disease
Protein glycosylation is vital to the regulation of cell function, and changes in this post-translational modification underlie many disease processes. In this Review, Chatham and Patel discuss how protein glycosylation contributes to normal cardiovascular function and its role in cardiovascular disease, identifying important knowledge gaps and areas for future research.
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Anticoagulants
Anticoagulant drugs are used to prevent and treat thrombotic disorders in millions of patients worldwide. This Milestone plots the history of anticoagulant drugs, starting with the discovery and clinical trials of heparin and warfarin.
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Graded exercise therapy should not be recommended for patients with post-exertional malaise
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Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
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Novel drug therapies for atrial fibrillation
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Sex-related similarities and differences in responses to heart failure therapies