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Innate IL-13 in virus-induced asthma?

Nature Immunology volume 12, pages 587–588 (2011)Cite this article

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Although the role of adaptive immunity in asthma is well characterized, there is relatively little understanding of the contribution of innate immunity to asthma. Studies now suggest that interleukin 13 produced by innate natural helper cells in the lungs has a substantial and underappreciated role in asthma exacerbation.

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Figure 1: Innate lymphoid cells produce IL-13 and mediate virus-induced AHR.

Katie Vicari

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Authors and Affiliations

  1. Stephania A. Cormier is in the Department of Pharmacology & Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA,

    Stephania A Cormier

  2. Jay K. Kolls is in the Department of Genetics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.,

    Jay K Kolls

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  1. Stephania A Cormier
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  2. Jay K Kolls
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Correspondence to Jay K Kolls.

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The authors declare no competing financial interests.

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Cormier, S., Kolls, J. Innate IL-13 in virus-induced asthma?. Nat Immunol 12, 587–588 (2011). https://doi.org/10.1038/ni.2056

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