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Metabolic remodelling in atrial fibrillation: manifestations, mechanisms and clinical implications
In this Review, the authors describe the changes in metabolism that predispose individuals to developing atrial fibrillation (AF) and highlight the potential of available and emerging therapeutic strategies that target metabolic remodelling to treat AF.
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Anticoagulants
Anticoagulant drugs are used to prevent and treat thrombotic disorders in millions of patients worldwide. This Milestone plots the history of anticoagulant drugs, starting with the discovery and clinical trials of heparin and warfarin.
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Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
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Graded exercise therapy should not be recommended for patients with post-exertional malaise
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Epidemiology of heart failure with preserved ejection fraction
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Epidemiology and modifiable risk factors for atrial fibrillation