WEB FOCUS

Marsupial genomics

Marsupial genomics cover

In this focus

Marsupials split off from the main mammalian lineage millions of years ago, and have been studied by biologists for years to discover what they can tell us about ancient mammals, particularly the evolution of mammalian sex chromosomes. Plus they are cute! The first marsupial genome has been sequenced and analysed from a tiny opossum named Monodelphis domestica. This Nature web focus presents the original research, and an archive of marsupial genetics and genomics.

Image: Larry Wadsworth, Media Resources, Texas A&M University.

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Current Research

ARTICLE

Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences Free access

Tarjei S. Mikkelsen et al.

Nature 447, 167—177 (10 May 2007) doi:10.1038/nature05805


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Evolutionary dynamics of transposable elements in the short-tailed opossum Monodelphis domestica

Gentles et al.


Characterization of the opossum immune genome provides insights into the evolution of the mammalian immune system

Belov et al.


An analysis of the gene complement of a marsupial, Monodelphis domestica: Evolution of lineage-specific genes and giant chromosomes

Goodstadt et al.


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ARCHIVE

LETTER

Retroviral invasion of the koala genome

Rachael E. Tarlinton, Joanne Meers & Paul R. Young

Nature 442, 79—81 (6 July 2006) doi:10.1038/nature04841


LETTER

Marsupial Y chromosome encodes a homologue of the mouse Y-linked candidate spermatogenesis gene Ube1y

Michael J. Mitchell, Diane R. Woods, Steven A. Wilcox, Jennifer A. Marshall Graves & Colin E. Bishop

Nature 359, 528—531 (8 Oct 1992) doi:10.1038/359528a0


LETTER

Evolution of sex determination and the Y chromosome: SRY-related sequences in marsupials

Jamie W. Foster et al.

Nature 359, 531—533 (8 Oct 1992) doi:10.1038/359531a0


LETTER

Sequences homologous to ZFY, a candidate human sex-determining gene, are autosomal in marsupials

Andrew H. Sinclair et al.

Nature 336, 780—783 (29 Dec 1988) doi:10.1038/336780a0


CORRESPONDENCE

The candidate spermatogenesis gene RBMY has a homologue on the human X chromosome

Margaret L. Delbridge, Patricia A. Lingenfelter, Christine M. Disteche & Jennifer A. Marshall Graves

Nature Genetics 22, 223—224 (1 Jul 1999) doi:10.1038/10279


ONCOGENOMICS

Marsupial BRCA1: conserved regions in mammals and the potential effect of missense changes

Christina J. Ramirez, Melissa A. Fleming, John D. Potter, Gary K. Ostrander & Elaine A. Ostrander

Oncogene 23, 1780—1788 (4 Mar 2004) doi:10.1038/sj.onc.1207292