Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
In this Perspective the authors survey the state of computerized cognitive training interventions for mental health and identify some of the challenges and opportunities in the scale-up of certain interventions.
The authors interrogate patterns of symptom-linked resting-state functional connectivity measured with electroencephalography with machine learning techniques to identify two dimensions associated with specific regions, the left angular gyrus and the right middle temporal gyrus and social and communication deficits, and the right inferior parietal lobe with restricted and repetitive disorders, which may serve as biomarkers in autism.
In this Review, the authors outline the current evidence on a precision medicine approach to Alzheimer’s disease risk reduction and propose how to integrate personalized strategies into routine clinical practice.
This longitudinal study of young people with parents with bipolar disorder assessed genetic and symptomatic risks associated with brain surface features, identifying reduced baseline frontotemporal cortical thickness in individuals who developed mood disorders at follow-up.
The authors conducted a systematic review and individual participant data meta-analysis of 14 studies to evaluate psychological interventions for depression relapse prevention.
Using a multivariate approach in a sample from the UK Biobank, the authors examine the genetic relationships between measures of functional connectivity and psychiatric disorders.
Inconsistent results have been obtained regarding the role of obesity and its related metabolic syndrome in neurological and psychiatric diseases. This systematic research using the UK Biobank demonstrates effects of body weight on the risk of several neurological and psychiatric disorders, and suggests that the higher risks may be partially explained by brain structure, food intake and inflammation.
Analyzing data on households without broadband internet access, level of urbanization, and mental healthcare services, the authors demonstrate that those counties with reduced broadband access are more likely to be under-resourced for mental health practitioners and facilities.
Modeling neurodevelopmental trajectories in a pediatric cohort reveals accelerated decrease in correlation between brain structural and functional connectivity in children exposed to high levels of prenatal adversity.
Using data from the UK Biobank, the authors studied the effect of body mass index, change in body mass index, and metabolic status in people with obesity on the prevalence of neurological and neuropsychiatric disorders.
Investigators present findings from a double-blind randomized controlled trial of personalized stimulation of the left dorsolateral prefrontal cortex using transcranial magnetic stimulation to increase hypnotizability in a sample of patients with fibromyalgia syndrome.
Clinical staging could be an actionable concept for behavioral and psychological symptoms of dementia (BPSD), providing clinicians with tools to navigate choices of treatment, acceptability of side effects and suitable care settings. This would pave the way for more research into tailored interventions that are much needed in high-stage BPSD.
This article explores debates in psychiatry about generalism and subspecialization, illustrating the potential benefits and issues of each in the context of service delivery and education founded on the biopsychosocial model. Recommendations are given to respond to varying global dynamics and support moves toward patient-centred care.
Instructions about nicotine strength influence smokers’ perception of the nicotine content in electronic cigarettes and are associated with neural responses in the thalamocortical system.
In this Q&A, we speak to Melissa Marselle, a member of the British Psychological Society’s Climate Environment Action Coordinating Group, which supports and advises on the implementation of effective climate change and environment work rooted in psychological evidence, and a lecturer of environmental psychology at the University of Surrey, UK. Her research examines the mental health benefits of contact with nature, with a specific focus on biodiversity.
The study reports the application of data-driven techniques to structural neuroimaging data of people with recent-onset psychosis or recent-onset depression and matched controls for the prediction of transdiagnostic clinical symptom severity and clinical outcomes.
Fittipaldi et al. examined how heterogeneity affects social cognition in populations over 50 years old by using advanced neuroimaging techniques and social cognition assessments in a diverse sample of over 1,000 adults across nine countries.