FOCUS
Autophagy
The January 2014 special issue on Autophagy brings together a series of authoritative reviews from outstanding experts in the field. The current understanding, as well as recent advances in various aspects of autophagy, its regulation, and their relevance to diseases, is presented. Further background information on this important topic is available through the accompanying web focus which links to related articles from across Nature Publishing Group.
Research Highlights
Unspliced XBP1 controls autophagy through FoxO1 FREE
Rene L Vidal and Claudio Hetz
Cell Res 23: 463-464; advance online publication, 22 January 2013; doi:10.1038/cr.2013.9
Common and divergent functions of Beclin 1 and Beclin 2 FREE
Lorenzo Galluzzi and Guido Kroemer
Cell Res 23: 1341-1342; advance online publication, 10 September 2013; doi:10.1038/cr.2013.129
Review
Receptor-mediated mitophagy in yeast and mammalian systems FREE
Lei Liu, Kaori Sakakibara, Quan Chen and Koji Okamoto
Cell Res 24: 787-795; advance online publication, 6 June 2014; doi:10.1038/cr.2014.75
Autophagy: for better or for worse FREE
Ellen Wirawan, Tom Vanden Berghe, Saskia Lippens, Patrizia Agostinis and Peter Vandenabeele
Cell Res 22: 43-61; advance online publication, 13 September 2011; doi:10.1038/cr.2011.152
Original Articles
Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion FREE
Jing Zhou, Shi-Hao Tan, Valérie Nicolas, Chantal Bauvy, Nai-Di Yang, Jianbin Zhang, Yuan Xue, Patrice Codogno and Han-Ming Shen
Cell Res 23: 508-523; advance online publication, 22 January 2013; doi:10.1038/cr.2013.11
XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells FREE
Ying Zhao, Xue Li, Mu-Yan Cai, Ke Ma, Jing Yang, Jingyi Zhou, Wan Fu, Fu-Zheng Wei, Lina Wang, Dan Xie and Wei-Guo Zhu
Cell Res 23: 491-507; advance online publication, 1 January 2013; doi:10.1038/cr.2013.2
ROS-induced DNA damage and PARP-1 are required for optimal induction of starvation-induced autophagy FREE
José Manuel Rodríguez-Vargas, María José Ruiz-Magaña, Carmen Ruiz-Ruiz, Jara Majuelos-Melguizo, Andreína Peralta-Leal, María Isabel Rodríguez, José Antonio Muñoz-Gámez, Mariano Ruiz de Almodóvar, Eva Siles, Abelardo López Rivas, Marja Jäättela and F Javier Oliver
Cell Res 22: 1181-1198; advance online publication, 24 April 2012; doi:10.1038/cr.2012.70
Steroid receptor coactivator 3 regulates autophagy in breast cancer cells through macrophage migration inhibitory factor FREE
Mei-Yi Wu, Junjiang Fu, Jianming Xu, Bert W O'Malley and Ray-Chang Wu
Cell Res 22: 1003-1021; advance online publication, 20 March 2012; doi:10.1038/cr.2012.44
Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein FREE
Weijiao Huang, Wooyoung Choi, Wanqiu Hu, Na Mi, Qiang Guo, Meisheng Ma, Mei Liu, Yuan Tian, Peilong Lu, Feng-Liang Wang, Haiteng Deng, Lei Liu, Ning Gao, Li Yu and Yigong Shi
Cell Res 22: 473-489; advance online publication, 7 February 2012; doi:10.1038/cr.2012.24
Functional interaction between autophagy and ciliogenesis
Olatz Pampliega, Idil Orhon, Bindi Patel, Sunandini Sridhar, Antonio Díaz-Carretero, Isabelle Beau, Patrice Codogno, Birgit H. Satir, Peter Satir and Ana Maria Cuervo
Nature 502: 194-200; advance online publication, 02 October 2013; doi:10.1038/nature12639
Autophagosomes form at ER-mitochondria contact sites
Maho Hamasaki, Nobumichi Furuta, Atsushi Matsuda, Akiko Nezu, Akitsugu Yamamoto, Naonobu Fujita, Hiroko Oomori, Takeshi Noda, Tokuko Haraguchi, Yasushi Hiraoka, Atsuo Amano and Tamotsu Yoshimori
Nature 495: 389-393; advance online publication, 03 March 2013; doi:10.1038/nature11910
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