STEM CELL RESEARCH

Stem cells possess the remarkable ability to self-renew and to differentiate into numerous specific cell lineages. Due to their critical importance in normal physiology and their potential to be used to develop regenerative therapies for a wide variety of diseases, stem cells have attracted extensive research interest in recent years. This focus features premium articles on stem cells recently published in Cell Research, a new and evolving strength of the journal, and it is a must-read for anyone with an interest in this exciting field

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Editorial

A Special Issue on Stem Cell Research FREE

Dangsheng Li and Gang Pei

Cell Res 17: 1–2; doi:10.1038/sj.cr.7310142

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Reviews

Regulation of hematopoiesis and the hematopoietic stem cell niche by Wnt signaling pathways FREE

Michael J Nemeth and David M Bodine

Cell Res 17: 746–758; doi:10.1038/cr.2007.69

Xeno-free derivation and culture of human embryonic stem cells: current status, problems and challenges FREE

Ting Lei, Sandrine Jacob, Imen Ajil-Zaraa, Jean-Bernard Dubuisson, Olivier Irion, Marisa Jaconi and Anis Feki

Cell Res 17: 682–688; doi:10.1038/cr.2007.61

Getting the right stuff: Controlling neural stem cell state and fate in vivo and in vitro with biomaterials FREE

Ana I Teixeira, Joshua K Duckworth and Ola Hermanson

Cell Res 17: 56–61; doi:10.1038/sj.cr.7310141

Thymic epithelial progenitor cells and thymus regeneration: an update FREE

Feng Li, Benjamin Tiede, Joan Massagué and Yibin Kang

Cell Res 17: 50–55; doi:10.1038/sj.cr.7310114

Nanog and transcriptional networks in embryonic stem cell pluripotency
Promoting human embryonic stem cell renewal or differentiation by modulating FREE

Guangjin Pan and James A Thomson

Cell Res 17: 42–49; doi:10.1038/sj.cr.7310125

Shp2-mediated molecular signaling in control of embryonic stem cell self-renewal and differentiation FREE

Gen–Sheng Feng

Cell Res 17: 37–41; doi:10.1038/sj.cr.7310140

Niche regulation of corneal epithelial stem cells at the limbus FREE

Wei Li, Yasutaka Hayashida, Ying-Ting Chen and Scheffer CG Tseng

Cell Res 17: 26–36; doi:10.1038/sj.cr.7310137

The Drosophila ovary: an active stem cell community FREE

Dániel Kirilly and Ting Xie

Cell Res 17: 15–25; doi:10.1038/sj.cr.7310123

Beyond tumorigenesis: cancer stem cells in metastasis FREE

Feng Li, Benjamin Tiede, Joan Massagué and Yibin Kang

Cell Res 17: 3–14; doi:10.1038/sj.cr.7310118

ABC transporters, neural stem cells and neurogenesis – a different perspective FREE

Tingting Lin, Omedul Islam and Klaus Heese

Cell Res 16: 857–871; doi:10.1038/sj.cr.7310107

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Original Articles

Activation of paternally expressed imprinted genes in newly derived germline–competent mouse parthenogenetic embryonic stem cell lines FREE

Hua Jiang, Bowen Sun, Weicheng Wang, Zhihong Zhang, Furong Gao, Guilai Shi, Bing Cui, Xiangyin Kong, Zhao He, Xiaoyan Ding, Ying Kuang, Jian Fei, Yi Juan Sun, Yun Feng and Ying Jin

Cell Res 17: 792–803; doi:10.1038/cr.2007.70

Quantitative and qualitative in vitro analysis of the stem cell potential of hematopoietic cells purified from murine skeletal muscle FREE

Celine Haond, Françoise Farace, Martine Guillier, Yann Lécluse, Frederic Mazurier, William Vainchenker and Ali G Turhan

Cell Res 17: 783–791; doi:10.1038/cr.2007.74

In vitro derivation of functional insulin-producing cells from human embryonic stem cells FREE

Wei Jiang, Yan Shi, Dongxin Zhao, Song Chen, Jun Yong, Jing Zhang, Tingting Qing, Xiaoning Sun, Peng Zhang, Mingxiao Ding, Dongsheng Li and Hongkui Deng

Cell Res 17: 333–344; doi:10.1038/cr.2007.28

Immunosuppressive properties of cloned bone marrow mesenchymal stem cells FREE

Guangwu Xu, Liying Zhang, Guangwen Ren, Zengrong Yuan, Yingyu Zhang, Robert C Zhao and Yufang Shi

Cell Res 17: 240–248; doi:10.1038/cr.2007.4

Anti-apoptotic effect of retinoic acid on retinal progenitor cells mediated by a protein kinase A-dependent mechanism FREE

Roman Kholodenko, Irina Kholodenko, Viktor Sorokin, Anna Tolmazova, Olga Sazonova and Anton Buzdin

Cell Res 17: 151–162; doi:10.1038/sj.cr.7310147

Nuclear reprogramming: the strategy used in normal development is also used in somatic cell nuclear transfer and parthenogenesis FREE

Tianlong Gao, Junke Zheng, Fengying Xing, Haiyan Fang, Feng Sun, Ayong Yan, Xun Gong, Hui Ding, Fan Tang and Hui Z Sheng

Cell Res 17: 135–150; doi:10.1038/cr.2007.2

Nuclear reprogramming: the zygotic transcription program is established through an "erase-and-rebuild" strategy FREE

Feng Sun, Haiyan Fang, Ruizhen Li, Tianlong Gao, Junke Zheng, Xuejin Chen, Wenqin Ying and Hui Z Sheng

Cell Res 17: 117–134; doi:10.1038/cr.2007.1

Establishment of customized mouse stem cell lines by sequential nuclear transfer FREE

Chunli Zhao, Ruqiang Yao, Jie Hao, Chenhui Ding, Yong Fan, Xiangpeng Dai, Wei Li, Tang Hai, Zichuan Liu, Yang Yu, Yingying Wang, Xiaojun Hou, Weizhi Ji, Qi Zhou, Alice Jouneau, Fanyi Zeng and Liu Wang

Cell Res 17: 80–87; advance online publication, January 9, 2007; doi:10.1038/sj.cr.7310139

Upregulation of Flk-1 by bFGF via the ERK pathway is essential for VEGF-mediated promotion of neural stem cell proliferation FREE

Zhifeng Xiao, Yaxian Kong, Shufa Yang, Meiyu Li, Jinhua Wen and Lingsong Li

Cell Res 17: 73–79; advance online publication, January 9, 2007; doi:10.1038/sj.cr.7310126

Promoting human embryonic stem cell renewal or differentiation by modulating Wnt signal and culture conditions FREE

Liuhong Cai, Zhaohui Ye, Betty Ying Zhou, Prashant Mali, Canquan Zhou and Linzhao Cheng

Cell Res 17: 62–72; doi:10.1038/sj.cr.7310138

Identification of key genes responsible for cytokine-induced erythroid and myeloid differentiation and switching of hematopoietic stem cells by RAGE FREE

Ling Chen, Hong Zhang, Ying Shi, Kyung L Chin, Delia C Tang and Griffin P Rodgers

Cell Res 16: 923–939; doi:10.1038/sj.cr.7310115

Differentiation profile of brain tumor stem cells: a comparative study with neural stem cells FREE

Quan Bin Zhang, Xiao Yan Ji, Qiang Huang, Jun Dong, Yu De Zhu and Qing Lan

Cell Res 16: 909–915; doi:10.1038/sj.cr.7310104

Skeletal myogenesis by human embryonic stem cells FREE

Jun Ke Zheng, Yi Wang, Aditi Karandikar, Qian Wang, Hui Gai, Ai Lian Liu, Chao Peng and Hui Zhen Sheng

Cell Res 16: 713–722; doi:10.1038/sj.cr.7310080

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