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MUCOSAL IMMUNOLOGY

Get the IL-17F outta here!

Nature Immunology volume 19, pages 648–650 (2018)Cite this article

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A Publisher Correction to this article was published on 01 February 2019

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The cytokine IL-17F constrains the growth of immunoregulatory Clostridium cluster XIVa species and represents a potential therapeutic target for the treatment of inflammatory bowel disease.

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Fig. 1: Modulation of gut microbiota by IL-17F.

Marina Corral Spence/Springer Nature

Change history

  • 01 February 2019

    In the version of this article initially published, a word (“neutraling”) in sentence 2 of paragraph 5 is incorrect. The correct phrase is “...neutralizing properties...”. The error has been corrected in the HTML and PDF version of the article.

References

  1. Tang, C. et al. Nat. Immunol. https://doi.org/10.1038/s41590-018-0134-y (2018).

  2. Ahern, P. P., Izcue, A., Maloy, K. J. & Powrie, F. Immunol. Rev. 226, 147–159 (2008).

    Article  Google Scholar 

  3. Lowes, M. A., Russell, C. B., Martin, D. A., Towne, J. E. & Krueger, J. G. Trends Immunol. 34, 174–181 (2013).

    Article  CAS  Google Scholar 

  4. Targan, S. R. et al. Am. J. Gastroenterol. 111, 1599–1607 (2016).

    Article  CAS  Google Scholar 

  5. Hueber, W. et al. Gut 61, 1693–1700 (2012).

    Article  CAS  Google Scholar 

  6. Sands, B. E. et al. Gastroenterology 153, 77–86.e6 (2017).

    Article  CAS  Google Scholar 

  7. Feagan, B. G. et al. Lancet 389, 1699–1709 (2017).

    Article  CAS  Google Scholar 

  8. Maxwell, J. R. et al. Immunity 43, 739–750 (2015).

    Article  CAS  Google Scholar 

  9. Miossec, P. & Kolls, J. K. Nat. Rev. Drug Discov. 11, nrd3794 (2012).

    Article  Google Scholar 

  10. Atarashi, K. et al. Science 331, 337–341 (2011).

    Article  CAS  Google Scholar 

  11. Paramsothy, S. et al. J. Crohn’s Colitis 11, 1180–1199 (2017).

    Article  Google Scholar 

  12. Fuentes, S. et al. ISME J. 11, 1877–1889 (2017).

    Article  Google Scholar 

  13. Paramsothy, S. et al. Lancet 389, 1218–1228 (2017).

    Article  Google Scholar 

Download references

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Authors and Affiliations

  1. Janssen Immunology Research and Development, Spring House, PA, USA

    Aisling O’Hara Hall & Scott E. Plevy

  2. Janssen Immunology Research and Development, San Diego, CA, USA

    Jennifer E. Towne

Authors
  1. Aisling O’Hara Hall
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  2. Jennifer E. Towne
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  3. Scott E. Plevy
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Correspondence to Scott E. Plevy.

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Competing interests

A.O.H., J.E.T. and S.E.P. are employed by Janssen Pharmaceutical Companies of Johnson and Johnson.

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Hall, A.O., Towne, J.E. & Plevy, S.E. Get the IL-17F outta here!. Nat Immunol 19, 648–650 (2018). https://doi.org/10.1038/s41590-018-0141-z

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