Establishment of the germ cell lineage requires post-transcriptional regulation of mRNAs, yet the underlying molecular mechanisms are not fully understood in vertebrates. A small-molecule inhibitor of germ cell formation reveals a noncanonical translation system used in zebrafish embryos.
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Mishima, Y. PAINTing translation. Nat Chem Biol 14, 832–833 (2018). https://doi.org/10.1038/s41589-018-0102-8
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DOI: https://doi.org/10.1038/s41589-018-0102-8