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Regenerative medicine

The clinical benefit of stem cells in cartilage regeneration

The results of a recent randomized, controlled study suggest than intra-articular injection of autologous stem cells collected from peripheral blood might improve the outcome of surgical approaches to regeneration of articular cartilage after injury. However, questions remain regarding the clinical benefit and feasibility of such an approach.

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Figure 1: Schematic diagram illustrating the novel approach to joint-surface regeneration described by Saw et al1.

References

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Acknowledgements

The authors would like to thank J. A. Schwartz of the Feinstein Institute for Medical Research, North Shore LIJ Health System, USA, for his contributions to this article.

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Correspondence to Daniel A. Grande.

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The authors declare no competing financial interests.

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Koutsoumbelis, S., Grande, D. The clinical benefit of stem cells in cartilage regeneration. Nat Rev Rheumatol 9, 265–266 (2013). https://doi.org/10.1038/nrrheum.2013.56

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