Schizophrenia is associated with several cognitive deficits, and the authors investigated whether prodromal cognitive training could reduce or prevent such deficits. They used a neonatal ventral hippocampal lesion rat model of schizophrenia — in adulthood, these rats have cognitive control impairments and altered intrahippocampal synchrony of neural oscillations. Cognitive training during adolescence prevented these abnormalities, pointing to a possible prophylactic strategy for people at risk of schizophrenia.