Octogenarians are a growing population of patients undergoing percutaneous coronary intervention (PCI) and, yet, they are under-represented in clinical trials. Wang et al. demonstrate the increasing need for PCI, but declining use of drug-eluting stents in this age group, despite associated reductions in mortality, myocardial infarction, and rehospitalization.
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References
Lee, P. Y., Alexander, K. P., Hammill, B. G., Pasquali, S. K. & Peterson, E. D. Representation of elderly persons and women in published randomized trials of acute coronary syndromes. JAMA 286, 708–713 (2001).
Wang, T. Y. et al. Percutaneous coronary intervention and drug-eluting stent use among patients ≥85 years of age in the United States. J. Am. Coll. Cardiol. 59, 105–112 (2012).
Kastrati, A. et al. Analysis of 14 trials comparing sirolimus-eluting stents with bare-metal stents. N. Engl. J. Med. 356, 1030–1039 (2007).
Aziz, A. et al. Evaluation of revascularization subtypes in octogenarians undergoing coronary artery bypass grafting. Circulation 120 (11 Suppl.), S65–S69 (2009).
Kozower, B. D. et al. Impact of complete revascularization on long-term survival after coronary artery bypass grafting in octogenarians. Ann. Thorac. Surg. 80, 112–116 (2005).
McKellar, S. H., Brown, M. L., Frye, R. L., Schaff, H. V. & Sundt, T. M. 3rd Comparison of coronary revascularization procedures in octogenarians: a systematic review and meta-analysis. Nat. Clin. Pract. Cardiovasc. Med. 5, 738–746 (2008).
Singh, M. et al. Mayo Clinic Risk Score for percutaneous coronary intervention predicts in-hospital mortality in patients undergoing coronary artery bypass graft surgery. Circulation 117, 356–362 (2008).
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Both authors researched data for the article, contributed to the discussion of the content and reviewed/edited the article before submission. M. Gössl wrote the article.
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Gössl, M., Holmes, D. Don't neglect the octogenarians—DES for everyone!?. Nat Rev Cardiol 9, 189–190 (2012). https://doi.org/10.1038/nrcardio.2012.22
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DOI: https://doi.org/10.1038/nrcardio.2012.22