Two methods are used to identify cis-regulatory sequences by looking at their function.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Davidson, E.H. & Erwin, D.H. Science 311, 796–800 (2006).
Forrester, W.C. et al. Genes Dev. 4, 1637–1649 (1990).
The ENCODE Project Consortium. Nature 489, 57–74 (2012).
Maurano, M.T. et al. Science 337, 1190–1195 (2012).
Chan, Y.F. et al. Science 327, 302–305 (2010).
Murtha, M. et al. Nat. Methods 11, 559–565 (2014).
Dickel, D.E. et al. Nat. Methods 11, 566–571 (2014).
Hardison, R.C. & Taylor, J. Nat. Rev. Genet. 13, 469–483 (2012).
Kwasnieski, J.C., Mogno, I., Myers, C.A., Corbo, J.C. & Cohen, B.A. Proc. Natl. Acad. Sci. USA 109, 19498–19503 (2012).
Kheradpour, P. et al. Genome Res. 23, 800–811 (2013).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Hardison, R. Discovering enhancers directly by activity. Nat Methods 11, 491–492 (2014). https://doi.org/10.1038/nmeth.2933
Published:
Issue Date:
DOI: https://doi.org/10.1038/nmeth.2933