Neutrophils can function as chief effector cells in inflammation but can also regulate excessive inflammatory responses by secreting anti-inflammatory cytokines. The acute-phase reactant SAA-1 seems to be pivotal in the control of such plasticity.
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Mattarollo, S., Smyth, M. A novel axis of innate immunity in cancer. Nat Immunol 11, 981–982 (2010). https://doi.org/10.1038/ni1110-981
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DOI: https://doi.org/10.1038/ni1110-981
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