The differentiation of monocytes is altered in cancer, which results in the unexpected conversion of a large proportion of monocytic myeloid-derived suppressor cells into polymorphonuclear myeloid-derived suppressor cells.
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Wynn, T. Myeloid-cell differentiation redefined in cancer. Nat Immunol 14, 197–199 (2013). https://doi.org/10.1038/ni.2539
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DOI: https://doi.org/10.1038/ni.2539
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