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How to make an old immune system young again

Antibodies that target blood stem cells can rejuvenate immune responses in mice.
  1. Heidi Ledford
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Old mice developed more youthful immune systems after scientists reduced aberrant stem cells in the aged animals1. The technique strengthened the old rodents’ responses to viral infection and lowered signs of inflammation.

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doi: https://doi.org/10.1038/d41586-024-00871-6

Read the related News & Views: ‘Anti-ageing antibodies revive the immune system’.

References

  1. Ross, J. B. et al. Nature https://doi.org/10.1038/s41586-024-07238-x (2024).

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  2. Rossi, D. J. et al. Proc. Natl Acad. Sci. USA 102, 9194–9199 (2005).

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