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Serum thrombospondin-1 serves as a novel biomarker and agonist of gemcitabine-based chemotherapy in intrahepatic cholangiocarcinoma
- Dong-yang Ding
- , Xiao-jie Gan
- & Sheng-xian Yuan
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Association between dietary inflammatory potential and mortality after cancer diagnosis in the Women’s Health Initiative
- Jiali Zheng
- , Fred K. Tabung
- & Susan E. Steck
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Perspective
| Open AccessThe importance of long-term follow up of participants in clinical trials
- Jack Cuzick
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Comment
| Open AccessAdditional consensus recommendations for conducting complex innovative trials of oncology agents: a post-pandemic perspective
- Sarah P. Blagden
- , Ly-Mee Yu
- & Louise C. Brown
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Review Article
| Open AccessUK Biobank: a globally important resource for cancer research
- Megan C. Conroy
- , Ben Lacey
- & Naomi E. Allen
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Article
| Open AccessTh2 cells inhibit growth of colon and pancreas cancers by promoting anti-tumorigenic responses from macrophages and eosinophils
- Damian Jacenik
- , Ioannis Karagiannidis
- & Ellen J. Beswick
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| Open AccessIntratumoral heterogeneity affects tumor regression and Ki67 proliferation index in perioperatively treated gastric carcinoma
- Magnus Kock am Brink
- , Laura Sophie Dunst
- & Christoph Röcken
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Capecitabine induces hand-foot syndrome through elevated thymidine phosphorylase-mediated locoregional toxicity and GSDME-driven pyroptosis that can be relieved by tipiracil
- Bingxue Yang
- , Xinran Xie
- & Shiyi Zhang
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Article
| Open AccessSerplulimab, a novel anti-PD-1 antibody, in patients with microsatellite instability-high solid tumours: an open-label, single-arm, multicentre, phase II trial
- Shukui Qin
- , Jin Li
- & Jun Zhu
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Article
| Open AccessEarly radiologic signal of responsiveness to immune checkpoint blockade in microsatellite-stable/mismatch repair-proficient metastatic colorectal cancer
- Sebastian Meltzer
- , Anne Negård
- & Anne Hansen Ree
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Breast cancer risk among thyroid cancer survivors and the role of I-131 treatment
- Thi-Van-Trinh Tran
- , Carole Rubino
- & Florent de Vathaire
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Article
| Open AccessBreast density is strongly associated with multiparametric magnetic resonance imaging biomarkers and pro-tumorigenic proteins in situ
- Peter Lundberg
- , Mikael F. Forsgren
- & Charlotta Dabrosin
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Article
| Open AccessRisk of developing a second primary cancer in male breast cancer survivors: a systematic review and meta-analysis
- Isaac Allen
- , Hend Hassan
- & Antonis C. Antoniou
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Review Article
| Open AccessInterpreting the results of noninferiority trials—a review
- Jack Cuzick
- & Peter Sasieni
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Validation of a novel risk score to predict early and late recurrence in solitary fibrous tumour
- Tatiana Georgiesh
- , Ninna Aggerholm-Pedersen
- & Kjetil Boye
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Article
| Open AccessPost-diagnostic health behaviour scores in relation to fatal prostate cancer
- Rebecca E. Graff
- , Crystal S. Langlais
- & Stacey A. Kenfield
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Perspective |
Extruded small extracellular vesicles: splinters of circulating tumour cells may promote cancer metastasis?
- Yuan Wan
- , Yi-Qiu Xia
- & Si-Yang Zheng
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Article
| Open AccessPatient trajectories after diagnosis of diffuse large B-cell lymphoma—a multistate modelling approach to estimate the chance of lasting remission
- Sara Ekberg
- , Michael Crowther
- & Sandra Eloranta
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Article
| Open AccessConfidence bands in survival analysis
- Michael C. Sachs
- , Adam Brand
- & Erin E. Gabriel
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Review Article |
Toll-like receptor 9 agonists and combination therapies: strategies to modulate the tumour immune microenvironment for systemic anti-tumour immunity
- Zhangchi Dongye
- , Jian Li
- & Yuzhang Wu
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Article |
Randomised, Phase II study of selumetinib, an oral inhibitor of MEK, in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer
- Mark K. Doherty
- , Vincent C. Tam
- & Jennifer J. Knox
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Article
| Open AccessAutoregulation of H+/lactate efflux prevents monocarboxylate transport (MCT) inhibitors from reducing glycolytic lactic acid production
- Wiktoria Blaszczak
- , Hannah Williams
- & Pawel Swietach
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Anthropometric traits and risk of multiple myeloma: a pooled prospective analysis
- Kimberly A. Bertrand
- , Lauren R. Teras
- & Brenda M. Birmann
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| Open AccessComprehensive multiplexed immune profiling of the ductal carcinoma in situ immune microenvironment regarding subsequent ipsilateral invasive breast cancer risk
- Mathilde M. Almekinders
- , Tycho Bismeijer
- & Alastair M. Thompson
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Pre-diagnosis and post-diagnosis dietary patterns and survival in women with ovarian cancer
- Naoko Sasamoto
- , Tianyi Wang
- & Holly R. Harris
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Discovery and validation of a transcriptional signature identifying homologous recombination-deficient breast, endometrial and ovarian cancers
- Guillaume Beinse
- , Pierre-Alexandre Just
- & Jérôme Alexandre
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Modulation of autophagy: a Phase II study of vorinostat plus hydroxychloroquine versus regorafenib in chemotherapy-refractory metastatic colorectal cancer (mCRC)
- Sukeshi Patel Arora
- , Laura Tenner
- & Devalingam Mahalingam
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Article
| Open AccessUse of anti-androgenic 5α-reductase inhibitors and risk of oesophageal and gastric cancer by histological type and anatomical sub-site
- Sirus Rabbani
- , Giola Santoni
- & Shao-Hua Xie
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Article
| Open AccessObtaining long-term stage-specific relative survival estimates in the presence of incomplete historical stage information
- Rachael Stannard
- , Paul C. Lambert
- & Mark J. Rutherford
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Article
| Open AccessAndrogen and oestrogen receptor co-expression determines the efficacy of hormone receptor-mediated radiosensitisation in breast cancer
- Anna R. Michmerhuizen
- , Lynn M. Lerner
- & Corey W. Speers
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Article
| Open AccessGene-expression profiles of pretreatment biopsies predict complete response of rectal cancer patients to preoperative chemoradiotherapy
- Georg Emons
- , Noam Auslander
- & Jochen Gaedcke
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Article
| Open AccessA first-in-human Phase I dose-escalation trial of the novel therapeutic peptide, ALM201, demonstrates a favourable safety profile in unselected patients with ovarian cancer and other advanced solid tumours
- Aya El Helali
- , Ruth Plummer
- & Richard H. Wilson
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Article
| Open AccessAnti-epileptic drugs and prostate cancer-specific mortality compared to non-users of anti-epileptic drugs in the Finnish Randomized Study of Screening for Prostate Cancer
- Jukka K. Salminen
- , Aino Mehtola
- & Teemu J. Murtola
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RANKL regulates testicular cancer growth and Denosumab treatment has suppressive effects on GCNIS and advanced seminoma
- Christine Hjorth Andreassen
- , Mette Lorenzen
- & Martin Blomberg Jensen
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| Open AccessMRI radiomics independent of clinical baseline characteristics and neoadjuvant treatment modalities predicts response to neoadjuvant therapy in rectal cancer
- Maxiaowei Song
- , Shuai Li
- & Weihu Wang
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| Open AccessLow probability of disease cure in advanced ovarian carcinomas before the PARP inhibitor era
- Benoit You
- , Lilian Van Wagensveld
- & Olivier Colomban
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Article
| Open AccessInvestigation of urinary volatile organic compounds as novel diagnostic and surveillance biomarkers of bladder cancer
- Lauren Lett
- , Michael George
- & Chris Probert
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Tumour growth rate improves tumour assessment and first-line systemic treatment decision-making for immunotherapy in patients with liver metastatic uveal melanoma
- Toulsie Ramtohul
- , Axel Cohen
- & Vincent Servois
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A systematic review and meta-analysis of toxicity and treatment outcomes with pharmacogenetic-guided dosing compared to standard of care BSA-based fluoropyrimidine dosing
- Sarah Glewis
- , Marliese Alexander
- & Michael Michael
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Perspective
| Open AccessRadiation-induced prodrug activation: extending combined modality therapy for some solid tumours
- Nicola J. Farrer
- , Geoff S. Higgins
- & Ian H. Kunkler
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Article
| Open AccessThe impact of anthracyclines in intermediate and high-risk HER2-negative early breast cancer—a pooled analysis of the randomised clinical trials PlanB and SUCCESS C
- Amelie de Gregorio
- , Wolfgang Janni
- & Nadia Harbeck
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| Open AccessEvaluation of tumour surveillance protocols and outcomes in von Hippel-Lindau disease in a national health service
- Eamonn R. Maher
- , Julian Adlard
- & Richard N. Sandford
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| Open AccessRandomised phase II trial of weekly ixabepilone ± biweekly bevacizumab for platinum-resistant or refractory ovarian/fallopian tube/primary peritoneal cancer
- Dana M. Roque
- , Eric R. Siegel
- & Alessandro D. Santin
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| Open AccessSocio-economic inequalities in cancer survival: how do they translate into Number of Life-Years Lost?
- Aimilia Exarchakou
- , Dimitra-Kleio Kipourou
- & Bernard Rachet
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| Open AccessAdenoma characteristics associated with post-polypectomy proximal colon cancer incidence: a retrospective cohort study
- Rhea Harewood
- , Kate Wooldrage
- & Amanda J. Cross
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Article
| Open AccessBreast cancer hypoxia in relation to prognosis and benefit from radiotherapy after breast-conserving surgery in a large, randomised trial with long-term follow-up
- Julia Tutzauer
- , Martin Sjöström
- & Annika Jögi
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Article
| Open AccessLiquid BIOpsy for MiNimal RESidual DiSease Detection in Head and Neck Squamous Cell Carcinoma (LIONESS)—a personalised circulating tumour DNA analysis in head and neck squamous cell carcinoma
- Susanne Flach
- , Karen Howarth
- & Philipp Baumeister
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Article
| Open AccessAdjuvant capecitabine-containing chemotherapy benefit and homologous recombination deficiency in early-stage triple-negative breast cancer patients
- Leonora W. de Boo
- , Katarzyna Jóźwiak
- & Sabine C. Linn
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Article
| Open AccessThe projected impact of the COVID-19 lockdown on breast cancer deaths in England due to the cessation of population screening: a national estimation
- Stephen W. Duffy
- , Farah Seedat
- & Anne Mackie