Perspective
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Open Access
Featured
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Article
| Open AccessRisk of cancer and serious disease in Danish patients with urgent referral for serious non-specific symptoms and signs of cancer in Funen 2014–2021
- Rasmus Birkholm Grønnemose
- , Per Syrak Hansen
- & Peter Thye-Rønn
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Perspective
| Open AccessA taxonomy of early diagnosis research to guide study design and funding prioritisation
- Emma Whitfield
- , Becky White
- & Georgios Lyratzopoulos
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Article |
Automatic retinoblastoma screening and surveillance using deep learning
- Ruiheng Zhang
- , Li Dong
- & Wenbin Wei
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Comment
| Open AccessProgress and priorities in reducing the time to cancer diagnosis
- B. D. Nicholson
- & G. Lyratzopoulos
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Article
| Open AccessApplying a genetic risk score for prostate cancer to men with lower urinary tract symptoms in primary care to predict prostate cancer diagnosis: a cohort study in the UK Biobank
- Harry D. Green
- , Samuel W. D. Merriel
- & Sarah E. R. Bailey
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Article
| Open AccessAssociations between diagnostic time intervals and health-related quality of life, clinical anxiety and depression in adolescents and young adults with cancer: cross-sectional analysis of the BRIGHTLIGHT cohort
- Alice S. Forster
- , Annie Herbert
- & Lorna A. Fern
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Article
| Open AccessRisk of cancer following primary care presentation with fatigue: a population-based cohort study of a quarter of a million patients
- Becky White
- , Meena Rafiq
- & Georgios Lyratzopoulos
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Article
| Open AccessDo presenting symptoms, use of pre-diagnostic endoscopy and risk of emergency cancer diagnosis vary by comorbidity burden and type in patients with colorectal cancer?
- Sara Benitez Majano
- , Georgios Lyratzopoulos
- & Cristina Renzi
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Article |
The use of biomarkers and HPV genotyping to improve diagnostic accuracy in women with a transformation zone type 3
- Kristyn Manley
- , Amit Patel
- & Andrew Wills
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Article
| Open AccessThe impact of changing risk thresholds on the number of people in England eligible for urgent investigation for possible cancer: an observational cross-sectional study
- Sarah F. Moore
- , Sarah J. Price
- & Willie Hamilton
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Review Article |
Timeliness of diagnosis and treatment: the challenge of childhood cancers
- Callum J. R. Mullen
- , Ronald D. Barr
- & Eduardo L. Franco
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Article
| Open AccessInequalities in the decline and recovery of pathological cancer diagnoses during the first six months of the COVID-19 pandemic: a population-based study
- Ashleigh C. Hamilton
- , David W. Donnelly
- & Helen G. Coleman
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Article
| Open AccessAnticipated help-seeking for cancer symptoms before and after the coronavirus pandemic: results from the Onco-barometer population survey in Spain
- Dafina Petrova
- , Marina Pollán
- & Maria-José Sánchez
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Editorial
| Open AccessEarly cancer diagnosis: reaching targets across whole populations amidst setbacks
- Valerie McCormack
- & Ajay Aggarwal
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Article
| Open AccessPlasma-based early screening and monitoring of EGFR mutations in NSCLC patients by a 3-color digital PCR assay
- Xiang Song
- , Jian Gong
- & Li Chu
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Article
| Open AccessThe association between unexpected weight loss and cancer diagnosis in primary care: a matched cohort analysis of 65,000 presentations
- Brian D. Nicholson
- , Willie Hamilton
- & Paul Aveyard
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Article
| Open AccessPredictive value of inflammatory markers for cancer diagnosis in primary care: a prospective cohort study using electronic health records
- Jessica Watson
- , Chris Salisbury
- & Willie Hamilton
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Article
| Open AccessWhole-colon investigation vs. flexible sigmoidoscopy for suspected colorectal cancer based on presenting symptoms and signs: a multicentre cohort study
- Amanda J. Cross
- , Kate Wooldrage
- & Wendy Atkin
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Article
| Open AccessThe value of using the faecal immunochemical test in general practice on patients presenting with non-alarm symptoms of colorectal cancer
- Jakob Søgaard Juul
- , Nete Hornung
- & Peter Vedsted
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Epidemiology
| Open AccessAnthropometric measurements and survival after a prostate cancer diagnosis
- Megan S Farris
- , Kerry S Courneya
- & Christine M Friedenreich
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Clinical Study
| Open AccessVariation in ‘fast-track’ referrals for suspected cancer by patient characteristic and cancer diagnosis: evidence from 670 000 patients with cancers of 35 different sites
- Y Zhou
- , S C Mendonca
- & G Lyratzopoulos
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Epidemiology
| Open AccessRisk-adjusted colorectal cancer screening using the FIT and routine screening data: development of a risk prediction model
- Jennifer Anne Cooper
- , Nick Parsons
- & Sian Taylor-Phillips
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Clinical Study
| Open AccessThe Improving Rural Cancer Outcomes Trial: a cluster-randomised controlled trial of a complex intervention to reduce time to diagnosis in rural cancer patients in Western Australia
- Jon D Emery
- , Victoria Gray
- & C D'Arcy J Holman
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Epidemiology
| Open AccessEvidence of advanced stage colorectal cancer with longer diagnostic intervals: a pooled analysis of seven primary care cohorts comprising 11 720 patients in five countries
- M L Tørring
- , P Murchie
- & G Rubin
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Genetics and Genomics
| Open AccessA comparative study of germline BRCA1 and BRCA2 mutation screening methods in use in 20 European clinical diagnostic laboratories
- Gillian Ellison
- , Andrew Wallace
- & Simon Patton
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Clinical Study
| Open AccessKnowledge or noise? Making sense of General Practitioners’ and Consultant use of 2-week-wait referrals for suspected cancer
- Conan Donnelly
- , Nigel Hart
- & Anna Gavin
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Clinical Study
| Open AccessHamburg-Glasgow classification: preoperative staging by combination of disseminated tumour load and systemic inflammation in oesophageal carcinoma
- Matthias Reeh
- , Tarik Ghadban
- & Yogesh K Vashist
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Molecular Diagnostics
| Open AccessDetection of phosphatidylserine-positive exosomes for the diagnosis of early-stage malignancies
- Raghava Sharma
- , Xianming Huang
- & Alan J Schroit
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Epidemiology
| Open AccessA cancer geography paradox? Poorer cancer outcomes with longer travelling times to healthcare facilities despite prompter diagnosis and treatment: a data-linkage study
- Melanie Turner
- , Shona Fielding
- & Peter Murchie
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Molecular Diagnostics
| Open AccessExtreme assay sensitivity in molecular diagnostics further unveils intratumour heterogeneity in metastatic colorectal cancer as well as artifactual low-frequency mutations in the KRAS gene
- Sara Mariani
- , Luca Bertero
- & Caterina Marchiò
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Epidemiology
| Open AccessImpact of body mass index on ovarian cancer survival varies by stage
- Elisa V Bandera
- , Valerie S Lee
- & Lawrence H Kushi
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Clinical Study
| Open AccessComorbid conditions delay diagnosis of colorectal cancer: a cohort study using electronic primary care records
- Luke T A Mounce
- , Sarah Price
- & William Hamilton
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Epidemiology
| Open AccessThe contribution of body mass index to appraisal delay in colorectal cancer diagnosis: a structural equation modelling study
- Karen E Dyer
- , Levent Dumenci
- & Jennifer Elston Lafata
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Clinical Study
| Open AccessEvaluating wait times from screening to breast cancer diagnosis among women undergoing organised assessment vs usual care
- Anna M Chiarelli
- , Derek Muradali
- & Claire MB Holloway
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Molecular Diagnostics
| Open AccessExamining the common aetiology of serous ovarian cancers and basal-like breast cancers using double primaries
- Colin B Begg
- , Megan S Rice
- & Shelley S Tworoger
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Clinical Study
| Open AccessDoes emergency presentation of cancer represent poor performance in primary care? Insights from a novel analysis of linked primary and secondary care data
- Peter Murchie
- , Sarah M Smith
- & Shona Fielding
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Clinical Study
| Open AccessComparison of outcomes following a cytological or histological diagnosis of malignant mesothelioma
- Sanjeevan Muruganandan
- , Helman Alfonso
- & Fraser Brims
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Epidemiology
| Open AccessBody weight trajectories and risk of oesophageal and gastric cardia adenocarcinomas: a pooled analysis of NIH-AARP and PLCO Studies
- Jessica L Petrick
- , Scott P Kelly
- & Michael B Cook
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Epidemiology
| Open AccessCirculating copper and zinc levels and risk of hepatobiliary cancers in Europeans
- Magdalena Stepien
- , David J Hughes
- & Mazda Jenab
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Clinical Study
| Open AccessComparison of two protocols for the management of asymptomatic postmenopausal women with adnexal tumours – a randomised controlled trial of RMI/RCOG vs Simple Rules
- Natalie Nunes
- , Gareth Ambler
- & Davor Jurkovic
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Genetics and Genomics
| Open AccessThe spectrum of EWSR1-rearranged neoplasms at a tertiary sarcoma centre; assessing 772 tumour specimens and the value of current ancillary molecular diagnostic modalities
- Jonathan Noujaim
- , Robin L Jones
- & Khin Thway
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Molecular Diagnostics
| Open AccessTesting breast cancer serum biomarkers for early detection and prognosis in pre-diagnosis samples
- Anna Kazarian
- , Oleg Blyuss
- & John F Timms
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Clinical Study
| Open AccessBetter resource utilisation and quality of care for ovarian cancer patients using internet-based pathology review
- S Kommoss
- , F Kommoss
- & J Pfisterer
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Molecular Diagnostics
| Open AccessBreast cancer in neurofibromatosis type 1: overrepresentation of unfavourable prognostic factors
- Elina Uusitalo
- , Roope A Kallionpää
- & Juha Peltonen
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Short Communication
| Open AccessIncorporating multiparametric MRI staging and the new histological Grade Group system improves risk-stratified detection of bone metastasis in prostate cancer
- David Thurtle
- , Ray C J Hsu
- & Tristan Barrett
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Epidemiology
| Open AccessPathogenesis and progression of oesophageal adenocarcinoma varies by prior diagnosis of Barrett’s oesophagus
- Michael B Cook
- , Jennifer Drahos
- & Christian C Abnet
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Molecular Diagnostics
| Open AccessNCCN-IPI score-independent prognostic potential of pretreatment uric acid levels for clinical outcome of diffuse large B-cell lymphoma patients
- Katharina T Prochazka
- , Thomas Melchardt
- & Martin Pichler
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Molecular Diagnostics
| Open AccessOvarian carcinoma diagnosis: the clinical impact of 15 years of change
- Stefan Kommoss
- , C Blake Gilks
- & Friedrich Kommoss
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Clinical Study
| Open AccessFast-track access to urologic care for patients with macroscopic haematuria is efficient and cost-effective: results from a prospective intervention study
- Fredrik Liedberg
- , Ulf Gerdtham
- & Mef Nilbert