Featured
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Molecular Diagnostics
| Open AccessMiR-23a/-24-induced gene silencing results in mesothelial cell integration of pancreatic cancer
- H Listing
- , W A Mardin
- & J Haier
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Molecular Diagnostics
| Open AccessmiR-1228 promotes the proliferation and metastasis of hepatoma cells through a p53 forward feedback loop
- Y Zhang
- , J Dai
- & H Tang
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Clinical Study
| Open AccessInfluence of segmental chromosome abnormalities on survival in children over the age of 12 months with unresectable localised peripheral neuroblastic tumours without MYCN amplification
- R Defferrari
- , K Mazzocco
- & G P Tonini
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Letter to the Editor
| Open AccessReply to ‘Comment on: The NQO1 polymorphism C609T (Pro187Ser) and cancer susceptibility: a comprehensive meta-analysis’
- B Lajin
- & A Alachkar
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Letter to the Editor
| Open AccessNeed for clarification of data in a recent meta-analysis on the association of NQO1 C609T polymorphism with cancer risk
- X Cao
- & W Shen
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Mini Review
| Open AccessEpigenetics in acute promyelocytic leukaemia pathogenesis and treatment response: A TRAnsition to targeted therapies
- M F Arteaga
- , J-H Mikesch
- & C W E So
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Genetics and Genomics
| Open AccessGenotranscriptomic meta-analysis of the Polycomb gene CBX2 in human cancers: initial evidence of an oncogenic role
- P-L Clermont
- , L Sun
- & C D Helgason
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Translational Therapeutics
| Open AccessExpression and DNA methylation of TNF, IFNG and FOXP3 in colorectal cancer and their prognostic significance
- S K Ganapathi
- , A D Beggs
- & D Kumar
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Molecular Diagnostics
| Open AccessKRAS mutational subtype and copy number predict in vitro response of human pancreatic cancer cell lines to MEK inhibition
- H Hamidi
- , M Lu
- & R S Finn
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Genetics and Genomics
| Open AccessThe roles of HOXD10 in the development and progression of head and neck squamous cell carcinoma (HNSCC)
- F Hakami
- , L Darda
- & K D Hunter
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Molecular Diagnostics
| Open Accessβ-Arrestin1 promotes the progression of chronic myeloid leukaemia by regulating BCR/ABL H4 acetylation
- R Qin
- , K Li
- & L Zou
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Genetics and Genomics
| Open AccessLINE-1 methylation in leukocyte DNA, interaction with phosphatidylethanolamine N-methyltransferase variants and bladder cancer risk
- S M Tajuddin
- , A F S Amaral
- & J Mosquera
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Genetics and Genomics
| Open AccessFrequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease
- D Leongamornlert
- , E Saunders
- & Z Kote-Jarai
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Genetics and Genomics
| Open AccessFGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium
- D Agarwal
- , S Pineda
- & R L Milne
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Letter to the Editor
| Open AccessDistribution of breast cancer risk from SNPs and classical risk factors in women of routine screening age in the UK
- A R Brentnall
- , D G Evans
- & J Cuzick
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Molecular Diagnostics
| Open AccessTriple negative breast carcinoma EGFR amplification is not associated with EGFR, Kras or ALK mutations
- V Secq
- , J Villeret
- & C Charpin
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Genetics and Genomics
| Open AccessImpact of rapid genetic counselling and testing on the decision to undergo immediate or delayed prophylactic mastectomy in newly diagnosed breast cancer patients: findings from a randomised controlled trial
- M R Wevers
- , N K Aaronson
- & M G E M Ausems
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Genetics and Genomics
| Open AccessBOADICEA breast cancer risk prediction model: updates to cancer incidences, tumour pathology and web interface
- A J Lee
- , A P Cunningham
- & A C Antoniou
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Translational Therapeutics
| Open AccessEpigenetic silencing of miRNA-9 is associated with HES1 oncogenic activity and poor prognosis of medulloblastoma
- G Fiaschetti
- , L Abela
- & M A Grotzer
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Genetics and Genomics
| Open AccessAn RNAi-based screen reveals PLK1, CDK1 and NDC80 as potential therapeutic targets in malignant pleural mesothelioma
- A Linton
- , Y Y Cheng
- & G Reid
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Editorial
| Open AccessJust another brick in the wall: unravelling the epigenetic mechanism underlying tumour initiation of testicular germ cell cancer
- R Buettner
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Molecular Diagnostics
| Open AccessEvidence that active demethylation mechanisms maintain the genome of carcinoma in situ cells hypomethylated in the adult testis
- D G Kristensen
- , J E Nielsen
- & K Almstrup
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Molecular Diagnostics
| Open AccessEpigenetic status of LINE-1 predicts clinical outcome in early-stage rectal cancer
- A Benard
- , C J H van de Velde
- & D S B Hoon
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Translational Therapeutics
| Open AccessAerosolised 5-azacytidine suppresses tumour growth and reprogrammes the epigenome in an orthotopic lung cancer model
- M D Reed
- , C S Tellez
- & S A Belinsky
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Genetics and Genomics
| Open AccessLoss of PTEN expression is an independent predictor of favourable survival in endometrial carcinomas
- A Akiyama-Abe
- , T Minaguchi
- & H Yoshikawa
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Short Communication
| Open AccessMutational analysis of Polycomb genes in solid tumours identifies PHC3 amplification as a possible cancer-driving genetic alteration
- F Crea
- , L Sun
- & C D Helgason
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Letter to the Editor
| Open AccessComment on ‘Allergy and acute leukaemia in children with Down syndrome: a population study. Report from the Mexican Inter Institutional Group for the Identification of the Causes of Childhood Leukaemia (MIGICCL)’ – Is increased surveillance by hypersensitive immune system a reality or myth?
- Z Aryan
- & N Rezaei
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Reply to Letter to the Editor
| Open AccessReply: Comment on ‘Allergy and acute leukaemia in children with Down syndrome: a population study. Report from the Mexican Inter-Institutional Group for the Identification of the Causes of Childhood Leukaemia (MIGICCL)’ – A reality or myth or two viewpoints about the association between allergies and acute leukaemia in Down syndrome children
- J C Núñez-Enríquez
- , A Fajardo-Gutiérrez
- & J M Mejía-Aranguré
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Molecular Diagnostics
| Open AccessLSD1-mediated epigenetic modification contributes to proliferation and metastasis of colon cancer
- J Ding
- , Z-M Zhang
- & Z-S Yan
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Molecular Diagnostics
| Open AccessSomatostatin Receptor 1, a novel EBV-associated CpG hypermethylated gene, contributes to the pathogenesis of EBV-associated gastric cancer
- J Zhao
- , Q Liang
- & J Yu
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Short Communication
| Open AccessAllergy and acute leukaemia in children with Down syndrome: a population study. Report from the Mexican inter-institutional group for the identification of the causes of childhood leukaemia
- J C Núñez-Enríquez
- , A Fajardo-Gutiérrez
- & J M Mejía-Aranguré
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Genetics and Genomics
| Open AccessVan-Gogh-like 2 antagonises the canonical WNT pathway and is methylated in colorectal cancers
- G Piazzi
- , M Selgrad
- & L Ricciardiello
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Genetics and Genomics
| Open AccessLow penetrance susceptibility to glioma is caused by the TP53 variant rs78378222
- V Enciso-Mora
- , F J Hosking
- & R S Houlston
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Molecular Diagnostics
| Open AccessING1b-inducible microRNA203 inhibits cell proliferation
- J Chen
- , U M Tran
- & K Riabowol
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Molecular Diagnostics
| Open AccessFrequent GNAS mutations in low-grade appendiceal mucinous neoplasms
- G Nishikawa
- , S Sekine
- & Y Kanai
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Mini Review
| Open AccessHistone deacetylase inhibitors as radiosensitisers: effects on DNA damage signalling and repair
- B Groselj
- , N L Sharma
- & A E Kiltie
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Molecular Diagnostics
| Open AccessPrognostic significance of aberrantly silenced ANPEP expression in prostate cancer
- K D Sørensen
- , M O Abildgaard
- & T F Ørntoft
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Genetics and Genomics
| Open AccessMale breast cancer, age and sex chromosome aneuploidy
- P A Jacobs
- , V Maloney
- & A J Swerdlow
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Molecular Diagnostics
| Open AccessThe epigenetic landscape of oral squamous cell carcinoma
- P V Jithesh
- , J M Risk
- & R J Shaw
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Genetics and Genomics
| Open AccessThe collagen prolyl hydroxylases are novel transcriptionally silenced genes in lymphoma
- E Hatzimichael
- , C Lo Nigro
- & T Crook
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Translational Therapeutics
| Open AccessEpigenetic remodelling of gene expression profiles of neoplastic and normal tissues: immunotherapeutic implications
- S Coral
- , A Covre
- & M Maio
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Genetics and Genomics
| Open AccessSite-specific CpG methylation in the CCAAT/enhancer binding protein delta (CEBPδ) CpG island in breast cancer is associated with metastatic relapse
- C Palmieri
- , M Monteverde
- & T Crook
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Molecular Diagnostics
| Open AccessMixed lineage leukaemia-4 regulates cell-cycle progression and cell viability and its depletion suppresses growth of xenografted tumour in vivo
- K I Ansari
- , S Kasiri
- & S S Mandal
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Molecular Diagnostics
| Open AccessMethylation of the calcium channel regulatory subunit α2δ-3 (CACNA2D3) predicts site-specific relapse in oestrogen receptor-positive primary breast carcinomas
- C Palmieri
- , B Rudraraju
- & T Crook
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Short Communication
| Open AccessChromosome instability and benefit from adjuvant anthracyclines in breast cancer
- A F Munro
- , C Twelves
- & J MS Bartlett
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Molecular Diagnostics
| Open AccessNT5E (CD73) is epigenetically regulated in malignant melanoma and associated with metastatic site specificity
- H Wang
- , S Lee
- & T Crook
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Molecular Diagnostics
| Open AccessPrognostic significance of chromosome 3 alterations determined by microsatellite analysis in uveal melanoma: a long-term follow-up study
- S Thomas
- , C Pütter
- & M Zeschnigk
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Translational Therapeutics
| Open AccessThe cyclin-dependent kinase inhibitor p57Kip2 is epigenetically regulated in carboplatin resistance and results in collateral sensitivity to the CDK inhibitor seliciclib in ovarian cancer
- H M Coley
- , N A M Safuwan
- & T Crook
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Genetics and Genomics
| Open AccessRenal cancer and pneumothorax risk in Birt–Hogg–Dubé syndrome; an analysis of 115 FLCN mutation carriers from 35 BHD families
- A C Houweling
- , L M Gijezen
- & F H Menko