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Protective effect of increased O-GlcNAc cycling against 6-OHDA induced Parkinson’s disease pathology
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The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons
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CHCHD2 up-regulation in Huntington disease mediates a compensatory protective response against oxidative stress
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miR-277 targets the proapoptotic gene-hid to ameliorate Aβ42-mediated neurodegeneration in Alzheimer’s model
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Screens in aging-relevant human ALS-motor neurons identify MAP4Ks as therapeutic targets for the disease
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Local production of reactive oxygen species drives vincristine-induced axon degeneration
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Negative modulation of mitochondrial calcium uniporter complex protects neurons against ferroptosis
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Pyruvate dehydrogenase kinase 1 protects against neuronal injury and memory loss in mouse models of diabetes
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ChemR23 activation attenuates cognitive impairment in chronic cerebral hypoperfusion by inhibiting NLRP3 inflammasome-induced neuronal pyroptosis
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Neuron-secreted NLGN3 ameliorates ischemic brain injury via activating Gαi1/3-Akt signaling
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Lamin A upregulation reorganizes the genome during rod photoreceptor degeneration
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RhoA balances microglial reactivity and survival during neuroinflammation
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Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush
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PPM1K mediates metabolic disorder of branched-chain amino acid and regulates cerebral ischemia-reperfusion injury by activating ferroptosis in neurons
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AraC interacts with p75NTR transmembrane domain to induce cell death of mature neurons
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Cyclin-dependent kinases regulate the adult nervous system via the one-carbon-metabolism
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Neutrophil extracellular traps aggravate neuronal endoplasmic reticulum stress and apoptosis via TLR9 after traumatic brain injury
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Upregulation of KLK8 contributes to CUMS-induced hippocampal neuronal apoptosis by cleaving NCAM1
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Multiple sclerosis plasma IgG aggregates induce complement-dependent neuronal apoptosis
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TREM2 deficiency in microglia accelerates photoreceptor cell death and immune cell infiltration following retinal detachment
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Blocking dPerk in the intestine suppresses neurodegeneration in a Drosophila model of Parkinson’s disease
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Crocetin antagonizes parthanatos in ischemic stroke via inhibiting NOX2 and preserving mitochondrial hexokinase-I
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Restoring mitochondrial cardiolipin homeostasis reduces cell death and promotes recovery after spinal cord injury
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Astrocyte-derived exosomal nicotinamide phosphoribosyltransferase (Nampt) ameliorates ischemic stroke injury by targeting AMPK/mTOR signaling to induce autophagy
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Diverse maturity-dependent and complementary anti-apoptotic brakes safeguard human iPSC-derived neurons from cell death
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Caspase-1 inhibition improves cognition without significantly altering amyloid and inflammation in aged Alzheimer disease mice
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Multi-target action of β-alanine protects cerebellar tissue from ischemic damage
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Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction
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SARM1 deletion in parvalbumin neurons is associated with autism-like behaviors in mice
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p21-activated kinase 4 controls the aggregation of α-synuclein by reducing the monomeric and aggregated forms of α-synuclein: involvement of the E3 ubiquitin ligase NEDD4-1
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Inhibiting multiple forms of cell death optimizes ganglion cells survival after retinal ischemia reperfusion injury
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Macrophage migration inhibitory factor (MIF) acetylation protects neurons from ischemic injury
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VDAC1 regulates neuronal cell loss after retinal trauma injury by a mitochondria-independent pathway
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Restoration of ER proteostasis attenuates remote apoptotic cell death after spinal cord injury by reducing autophagosome overload
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NOX activation in reactive astrocytes regulates astrocytic LCN2 expression and neurodegeneration
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Ischemia-induced cleavage of OPA1 at S1 site aggravates mitochondrial fragmentation and reperfusion injury in neurons
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Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice
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Redefining the role of Ca2+-permeable channels in photoreceptor degeneration using diltiazem
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Oligodendrocytes depend on MCL-1 to prevent spontaneous apoptosis and white matter degeneration
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Cofilin1 oxidation links oxidative distress to mitochondrial demise and neuronal cell death
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Alpha-Synuclein defects autophagy by impairing SNAP29-mediated autophagosome-lysosome fusion
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Increased expression of fragmented tRNA promoted neuronal necrosis
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BCLXL gene therapy moderates neuropathology in the DBA/2J mouse model of inherited glaucoma
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Fibrillar α-synuclein induces neurotoxic astrocyte activation via RIP kinase signaling and NF-κB
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DJ-1 inhibits microglial activation and protects dopaminergic neurons in vitro and in vivo through interacting with microglial p65
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Primed to die: an investigation of the genetic mechanisms underlying noise-induced hearing loss and cochlear damage in homozygous Foxo3-knockout mice
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Parp mutations protect from mitochondrial toxicity in Alzheimer’s disease
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Hypoxic postconditioning promotes mitophagy against transient global cerebral ischemia via PINK1/Parkin-induced mitochondrial ubiquitination in adult rats
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Pirh2 modulates the mitochondrial function and cytochrome c-mediated neuronal death during Alzheimer’s disease