Featured
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Patterns of genomic change in residual disease after neoadjuvant chemotherapy for estrogen receptor-positive and HER2-negative breast cancer
- Aikaterini Chatzipli
- , Hervé Bonnefoi
- & Richard Iggo
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Article
| Open AccessWhole-genome sequencing facilitates patient-specific quantitative PCR-based minimal residual disease monitoring in acute lymphoblastic leukaemia, neuroblastoma and Ewing sarcoma
- Vinod Vijay Subhash
- , Libby Huang
- & Toby N. Trahair
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Identification of putative actionable alterations in clinically relevant genes in breast cancer
- Pushpinder Kaur
- , Tania B. Porras
- & Julie E. Lang
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Depiction of the genomic and genetic landscape identifies CCL5 as a protective factor in colorectal neuroendocrine carcinoma
- Dong Chen
- , Xuanwen Bao
- & Peng Zhao
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Article |
TP53 mutations increase radioresistance in rhabdomyosarcoma and Ewing sarcoma
- Dana L. Casey
- , Kenneth L. Pitter
- & Suzanne L. Wolden
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Editorial |
Profiling circulating tumour cells and cell free DNA together in metastatic colon cancer
- Thomas Friend
- & Justin Stebbing
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Comment |
Personalising care in oesophageal cancer care with liquid biopsy
- Bruno De Paula
- & Elizabeth C Smyth
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Comment |
Bridging the gap between cancer cell line models and tumours using gene expression data
- Javad Noorbakhsh
- , Francisca Vazquez
- & James M. McFarland
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Review Article
| Open AccessPromises and challenges of adoptive T-cell therapies for solid tumours
- Matteo Morotti
- , Ashwag Albukhari
- & Ahmed A. Ahmed
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Article
| Open AccessFrequent post-operative monitoring of colorectal cancer using individualised ctDNA validated by multiregional molecular profiling
- Mizunori Yaegashi
- , Takeshi Iwaya
- & Satoshi S. Nishizuka
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Comment
| Open AccessUnderstanding the impact of immune-mediated selection on lung cancer evolution
- Rachel Rosenthal
- , Charles Swanton
- & Nicholas McGranahan
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Comment
| Open AccessTransforming the landscape of early cancer detection using blood tests—Commentary on current methodologies and future prospects
- Minetta C. Liu
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Review Article
| Open AccessMutational drivers of cancer cell migration and invasion
- Nikita M. Novikov
- , Sofia Y. Zolotaryova
- & Evgeny V. Denisov
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Comment
| Open AccessPractical early cancer detection: distinguishing stable from unstable genomes in pre-cancerous tissues
- Sarah Killcoyne
- & Rebecca C. Fitzgerald
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Article
| Open AccessA balance score between immune stimulatory and suppressive microenvironments identifies mediators of tumour immunity and predicts pan-cancer survival
- Tolga Turan
- , Sarah Kongpachith
- & Michele Ceccarelli
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Article
| Open AccessEpigenome-wide analysis reveals functional modulators of drug sensitivity and post-treatment survival in chronic lymphocytic leukaemia
- Timothy M. Barrow
- , Sirintra Nakjang
- & Gordon Strathdee
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Article
| Open AccessDroplet-digital PCR reveals frequent mutations in TERT promoter region in breast fibroadenomas and phyllodes tumours, irrespective of the presence of MED12 mutations
- Kazutaka Otsuji
- , Takeshi Sasaki
- & Yasuyuki Seto
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Article
| Open AccessArtificial selection for host resistance to tumour growth and subsequent cancer cell adaptations: an evolutionary arms race
- Arig Ibrahim-Hashim
- , Kimberly Luddy
- & Robert A. Gatenby
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Article
| Open AccessClinically and biologically relevant subgroups of Wilms tumour defined by genomic and epigenomic analyses
- Jack Brzezinski
- , Sanaa Choufani
- & Rosanna Weksberg
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Article
| Open AccessPopulation-scale predictions of DPD and TPMT phenotypes using a quantitative pharmacogene-specific ensemble classifier
- Yitian Zhou
- , Carolina Dagli Hernandez
- & Volker M. Lauschke
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Article
| Open AccessLongitudinal monitoring of circulating tumour DNA improves prognostication and relapse detection in gastroesophageal adenocarcinoma
- Mark R. Openshaw
- , Ali Abdulnabi Suwaidan
- & Jacqui A. Shaw
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Correspondence
| Open AccessComment on: “UGT2B17 modifies drug response in chronic lymphocytic leukaemia”
- Spyros I. Papamichos
- & Christof Jungbauer
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Article
| Open AccessA comprehensive population-based study comparing the phenotype and genotype in a pretherapeutic screen of dihydropyrimidine dehydrogenase deficiency
- Nicolas Pallet
- , Salma Hamdane
- & Céline Narjoz
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Article
| Open AccessClinical utility of serial analysis of circulating tumour cells for detection of minimal residual disease of metastatic nasopharyngeal carcinoma
- Josephine Mun-Yee Ko
- , Vince Vardhanabhuti
- & Maria Li Lung
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Review Article
| Open AccessEmerging role of PTEN loss in evasion of the immune response to tumours
- Thiago Vidotto
- , Camila Morais Melo
- & Jeremy A. Squire
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Article
| Open AccessGenetic heterogeneity and evolutionary history of high-grade ovarian carcinoma and matched distant metastases
- Tariq Masoodi
- , Sarah Siraj
- & Khawla S. Al-Kuraya
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Review Article
| Open AccessThe roles of RNA in DNA double-strand break repair
- Aldo S. Bader
- , Ben R. Hawley
- & Martin Bushell
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Review Article
| Open AccessDefining a metabolic landscape of tumours: genome meets metabolism
- Chandan Seth Nanda
- , Sharavan Vishaan Venkateswaran
- & Mariia Yuneva
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Article
| Open AccessTranscriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin
- Simon R. Lord
- , Jennifer M. Collins
- & Adrian L. Harris
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Article
| Open AccessNongenic cancer-risk SNPs affect oncogenes, tumour-suppressor genes, and immune function
- Maud Fagny
- , John Platig
- & John Quackenbush
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Review Article
| Open AccessThe effect of co-occurring lesions on leukaemogenesis and drug response in T-ALL and ETP-ALL
- Paniz Tavakoli Shirazi
- , Laura N. Eadie
- & Deborah L. White
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Brief Communication
| Open AccessMonozygotic twins with neuroblastoma MS have a similar molecular profile: a case of twin-to-twin metastasis
- Margaret Shatara
- , Ana C. Xavier
- & Jeffrey W. Taub
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Article
| Open AccessSignet ring cell colorectal cancer: genomic insights into a rare subpopulation of colorectal adenocarcinoma
- Krittiya Korphaisarn
- , Van Morris
- & Scott Kopetz
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Brief Communication
| Open AccessMolecular portrait of high alpha-fetoprotein in hepatocellular carcinoma: implications for biomarker-driven clinical trials
- Robert Montal
- , Carmen Andreu-Oller
- & Josep M. Llovet
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Article
| Open AccessPlasma total cell-free DNA is a prognostic biomarker of overall survival in metastatic solid tumour patients
- Ida Viller Tuxen
- , Lise Barlebo Ahlborn
- & Ulrik Lassen
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Article
| Open AccessTranscriptional and metabolic rewiring of colorectal cancer cells expressing the oncogenic KRASG13D mutation
- Theodosia Charitou
- , Sriganesh Srihari
- & David J. Lynn
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Brief Communication
| Open AccessMolecular tumour boards and molecular diagnostics for patients with cancer in the Netherlands: experiences, challenges, and aspirations
- Annelieke E. C. A. B. Willemsen
- , Sarah Krausz
- & Carla M. L. van Herpen
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Article
| Open AccessA key genomic subtype associated with lymphovascular invasion in invasive breast cancer
- Sasagu Kurozumi
- , Chitra Joseph
- & Emad A Rakha
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Article
| Open AccessA multicentre, prospective study of plasma circulating tumour DNA test for detecting RAS mutation in patients with metastatic colorectal cancer
- Hideaki Bando
- , Yoshinori Kagawa
- & Takayuki Yoshino
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Article
| Open AccessPhase 1 trial of dasatinib combined with afatinib for epidermal growth factor receptor- (EGFR-) mutated lung cancer with acquired tyrosine kinase inhibitor (TKI) resistance
- Ben C. Creelan
- , Jhanelle E. Gray
- & Eric B. Haura
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Article
| Open AccessMolecular heterogeneity and early metastatic clone selection in testicular germ cell cancer development
- Lambert C. J. Dorssers
- , Ad J. M. Gillis
- & Leendert H. J. Looijenga
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Review Article
| Open AccessMolecular characterisation and liquid biomarkers in Carcinoma of Unknown Primary (CUP): taking the ‘U’ out of ‘CUP’
- Alicia-Marie Conway
- , Claire Mitchell
- & Natalie Cook
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Article
| Open AccessExploring the transcriptome of hormone-naive multifocal prostate cancer and matched lymph node metastases
- Linnéa Schmidt
- , Mia Møller
- & Karina Dalsgaard Sørensen
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Article
| Open AccessTarget-based therapeutic matching of phase I trials in patients with metastatic breast cancer in a tertiary referral centre
- Brent O’Carrigan
- , Joline Si Jing Lim
- & Timothy Anthony Yap
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Article
| Open AccessPhase II trial of palbociclib in patients with metastatic urothelial cancer after failure of first-line chemotherapy
- Tracy L. Rose
- , David D. Chism
- & Matthew I. Milowsky
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Article
| Open AccessCharacteristics of The Cancer Genome Atlas cases relative to U.S. general population cancer cases
- Xiaoyan Wang
- , Joseph T. Steensma
- & Kimberly J. Johnson
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Brief Communication
| Open AccessDetection of circulating tumour cell clusters in human glioblastoma
- Ilona Krol
- , Francesc Castro-Giner
- & Nicola Aceto
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Article
| Open AccessIntegrative analysis of oncogenic fusion genes and their functional impact in colorectal cancer
- Yuri Choi
- , Chae Hwa Kwon
- & Do Youn Park
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Article
| Open AccessCancer subtype identification using somatic mutation data
- Marieke Lydia Kuijjer
- , Joseph Nathaniel Paulson
- & John Quackenbush