Biomedical engineering articles within Nature

Featured

  • Article |

    Newly developed microfluidic neural tube-like and forebrain-like structures based on human pluripotent stem cells can model pivotal aspects of neural patterning along both the rostral–caudal and dorsal–ventral axes.

    • Xufeng Xue
    • , Yung Su Kim
    •  & Jianping Fu

  • Article |

    Water-responsive supercontractile polymer films composed of poly(ethylene oxide) and poly(ethylene glycol)-α-cyclodextrin inclusion complex contract by more than 50% of their original length within seconds after wetting and become soft and stretchable hydrogel thin films that can be used in bioelectronic interfaces.

    • Junqi Yi
    • , Guijin Zou
    •  & Xiaodong Chen

  • Article |

    An injectable hydrogel for use as a scaffold to aid tissue repair is described, the material of which is conductive so that it can be used both for electrophysiological measurement and electrostimulation in closed-loop robot-assisted rehabilitation.

    • Subin Jin
    • , Heewon Choi
    •  & Mikyung Shin

  • Article |

    A handheld printed circuit board-based programmable platform using ferrobots can perform the complex, laboratory-equivalent procedures involved in multiplexed and pooled nucleic acid amplification testing, allowing for the decentralization of viral diagnostics.

    • Haisong Lin
    • , Wenzhuo Yu
    •  & Sam Emaminejad

  • Article |

    Lateral-flow in vitro diagnostic assays based on fluorescent nanodiamonds, in which microwave-based spin manipulation is used to increase sensitivity, are demonstrated using the biotin–avidin model and by the single-copy detection of HIV-1 RNA.

    • Benjamin S. Miller
    • , Léonard Bezinge
    •  & Rachel A. McKendry

  • Article |

    Miniature gut tubes grown in vitro from mouse intestinal stem cells are perfusable, can be colonized with microorganisms and exhibit a similar arrangement and diversity of specialized cell types to intestines in vivo.

    • Mikhail Nikolaev
    • , Olga Mitrofanova
    •  & Matthias P. Lutolf

  • Article |

    A new strong, biocompatible and biodegradable double-sided tape can adhere to wet tissues and devices through a mechanism involving rapid water removal from the surface, swift hydrogen and electrostatic interactions, and covalent bonding.

    • Hyunwoo Yuk
    • , Claudia E. Varela
    •  & Xuanhe Zhao

  • Letter |

    Cell-labelling experiments are used to demonstrate that the hindgut in the chick embryo is formed by cells moving through the stationary caudal intestinal portal as a result of a contractile force gradient directed by fibroblast growth factor signalling.

    • Nandan L. Nerurkar
    • , ChangHee Lee
    •  & Clifford J. Tabin

  • Letter |

    A tissue culture system that provides an increasing intensity of electromechanical stimulation over time enables an in vitro model of cardiac tissue derived from human induced pluripotent stem cells to develop many of the characteristics of adult cardiac tissue.

    • Kacey Ronaldson-Bouchard
    • , Stephen P. Ma
    •  & Gordana Vunjak-Novakovic

  • Letter |

    Electronic implants are often used in diagnosing and treating human illness, but permanent implants come with problems; here, devices are described that can sense temperature, pressure, pH or thermal characteristics, and—crucially—are fully resorbable by the body.

    • Seung-Kyun Kang
    • , Rory K. J. Murphy
    •  & John A. Rogers

  • Letter |

    Conventional clinical ultrasound imaging has, at best, sub-millimetre-scale resolution, but now a new ultrasound technique is demonstrated that is based on fast tracking of transient signals from a sub-wavelength contrast agent and has sufficiently high resolution to map the microvasculature deep into organs.

    • Claudia Errico
    • , Juliette Pierre
    •  & Mickael Tanter

  • Outlook |

    Prized for their versatility, optical properties and safety, gold nanoparticles are helping to image, diagnose and treat disease.

    • Karen Weintraub

  • News Q&A |

    Gary Gibbons, the next director of the US National Heart, Lung, and Blood Institute, hopes to diversify the biomedical workforce.

    • Amy Maxmen

  • News & Views |

    An elastic polymer has been made whose molecular structure mimics that of titin, a protein found in muscle. The resulting material is tough, stretchy and dissipates energy — just like muscle itself.

    • Elliot L. Chaikof

  • Books & Arts |

    Engineering biological systems and organisms is a costly team effort and may be incompatible with an open-source regulatory environment, finds Michael A. Goldman.

    • Michael A. Goldman

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