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Molecular biomarker approaches to prevention of post-traumatic osteoarthritis
Early identification of osteoarthritis (OA) prior to the development of symptoms is challenging. Post-traumatic OA provides a model for the development of OA following a defined event. In this Review, the authors describe the existing knowledge relating to the biomarkers of post-traumatic OA, which might also be applicable to the identification of early non-traumatic OA.
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![25 years of biologic therapy](https://media.springernature.com/lw630/nature-cms/uploads/collections/25_Hero_-_Collection-cc67dc7cbc8f54e78598a9c6264fa473.jpg)
25 years of biologic therapy
Biologic therapies with various modes of action have been introduced into the field of rheumatology over the past 25 years, and have revolutionized the treatment and outcomes in many rheumatic diseases. This collection from Nature Reviews Rheumatology brings together articles on biologic therapy in rheumatology, including the latest Reviews and Opinion pieces, as well as popular content from our archives.