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This study reports the identification of an archaeal virus Acr protein that blocks the dissociation of the target RNA from the type III-B CRISPR–Cas effector complex, which prevents the recycling of the complex.
In this study, Wang et al. show that bacterium-derived intestinal ammonia modulates glutamine production in the mouse brain and reduces stress-induced depressive-like behaviour.
In this study, Simonis et al. show that chronic infection with Pseudomonas aeruginosa leads to development of neutralizing antibodies that could be exploited to fight against this pathogen.
This Genome Watch highlights how a tailor-made search through bacterial genomes revealed the widespread presence of a new class of bacterial signalling peptides that lack conventional characteristics.
In this Review, Maillard and Pascoe examine the mechanisms of action of biocides, as well as the bacterial intrinsic and acquired resistance to these biocides and its implications in environmental and clinical settings.
In this Review, Castañeda-Barba, Top and Stalder use the One Health framework to synthesize the recent literature on the ecological and evolutionary factors that determine the successful local and global spread of plasmid-mediated antimicrobial resistance genes.
In this Review, Margolin and Cameron explore how the divisome of Escherichia coli is assembled and activated to modulate the division process, and discuss how the divisome machinery can be targeted for therapeutic purposes.
In this Review, Lass-Flörl and Govrins explore the epidemiology, clinical manifestations and antifungal resistance of the Candida parapsilosis complex, and discuss diagnostics and new treatment approaches to tackle infections by these human pathogens.
