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Collection: Antimicrobial resistance: a silent pandemic
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Collection: The Clinical Microbiome
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MAVS is a sensor of fumarate during antiviral immunity
Viral infection of macrophages causes metabolic rewiring, increasing the level of cytosolic fumarate owing to increased argininosuccinate synthase 1 expression. Fumarate succinates mitochondrial antiviral-signalling protein, promoting its ability to drive type I interferon production and antiviral immunity.
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Dairy cows develop protective immunity against reinfection with bovine H5N1 influenza virus
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Host AAA-ATPase VCP/p97 lyses ubiquitinated intracellular bacteria as an innate antimicrobial defence
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Phollow reveals in situ phage transmission dynamics in the zebrafish gut microbiome at single-virion resolution
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Communicating the promise of phage therapy