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Primal FEAR protects against infection

FEAR is an ancestral histone chaperone complex that can control virus infections in an interferon-independent manner.

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Fig. 1: IFN versus FEAR response mechanisms.

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Acknowledgements

Work in the Walsh lab is supported by funding from the National Institutes of Health, grant numbers R01 AI127456, R01 AI179744 and R01 AI141470.

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Correspondence to Derek Walsh.

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Walsh, D. Primal FEAR protects against infection. Nat Microbiol 9, 886–888 (2024). https://doi.org/10.1038/s41564-024-01649-2

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