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Domestic cats’ voice boxes can sustain purring sound without requiring input from muscles or the brain. Plus, researchers have a rare opportunity to make progress in protecting global biodiversity and rings of RNA could be the next blockbuster drug.
Analysis of high-resolution annual data shows that global human settlements have expanded continuously and rapidly into flood zones, with those in the most hazardous zones increasing by 122% from 1985 to 2015.
Silicate weathering of uplifted rock depletes atmospheric CO2, but oxidation of revealed rock organic carbon supplies CO2, offsetting depletion to a degree dependent on regional geological history.
Assembly theory conceptualizes objects as entities defined by their possible formation histories, allowing a unified language for describing selection, evolution and the generation of novelty.
Comparisons of phenotypic and genetic association with protein levels from Icelandic and UK Biobank cohorts show that using multiple analysis platforms and stratifying populations by ancestry improves the detection of associations and allows the refinement of their location within the genome.
This study presents a continuous fossil record, extracted from a series of sediment cores, that shows how haplochromine cichlids came to dominate the fish fauna of Lake Victoria in Africa.
An orally bioavailable small-molecule active-site inhibitor of the phosphatases PTPN2 and PTPN1, ABBV-CLS-484, demonstrates immunotherapeutic efficacy in mouse models of cancer resistant to PD-1 blockade.
Although the catalogue of human protein-coding genes is nearing completion, the number of non-coding RNA genes remains highly uncertain, and for all genes much work remains to be done to understand their functions.
A set of three papers in Nature reports a new proteomics resource from the UK Biobank and initial analysis of common and rare genetic variant associations with plasma protein levels.
Binding of a sialoglycan-based primary receptor by the spike protein of the common cold human coronavirus HKU1 triggers conformational changes to a state that would allow binding to a second receptor required for cell entry.
Asynchronous flight in all major groups of insects likely arose from a single common ancestor with reversions to a synchronous flight mode enabled by shifts back and forth between different regimes in the same set of dynamic parameters.
The second Global Amphibian Assessment finds that the status of amphibians is continuing to deteriorate globally, driven predominantly by climate change, disease and habitat loss.
A high-precision, high-field test of quantum electrodynamics measuring the bound-electron g factor in hydrogen-like tin is described, which—together with state-of-the-art theory calculations—yields a stringent test in the strong-field regime.