Browse Articles

CRISPR screening and protein–protein interaction networks identify components and mechanisms of nutrient-dependent mTORC1 signalling in regulatory T cells and reveal how mTORC1 integrates immunological cues and nutrient signals for adaptive immunity.

Our quest to bring a child into our family led us to confront academic working practices, say Tony Ly and Nathan W. Bailey.

A mechanism known as ‘original antigenic sin' protects some people from flu; whether it helps immune reactions to coronaviruses is still unclear.

In a worst-case scenario, the pandemic could cause a further 300,000 deaths if anti-contagion policies are lifted and people revert to their old habits.

Experiments with various types of glove identify the factors behind a successful finger click.

To remain globally competitive, the country must regain an edge in emerging fields.

Spineless sea squirts shed light on vertebrate evolution, and an iodine-fuelled engine powering a satellite in space.

A description of the terminology and methodology used in this supplement, and a guide to the functionality that is available free online at natureindex.com.

A keystone aquatic species develops resistance to compounds used to treat organic fields near its ponds.

The presence of porcine deltacoronavirus has been detected in three children from Haiti that could have originated from zoonotic spillover.

Characterizations of bacteria under acute stress reveal features that can be predicted using a conceptual model of physical ageing. 

The successful in-orbit operation of an electric space propulsion system based on iodine, rather than the more expensive and difficult-to-store xenon, is demonstrated.

A new technique called immunoGAM, which combines genome architecture mapping (GAM) with immunoselection, enabled the discovery of specialized chromatin conformations linked to gene expression in specific cell populations from mouse brain tissues.

Structural studies of the itch receptors MRGPRX2 and MRGPRX4 in complex with endogenous and synthetic ligands provide a basis for the development of therapeutic compounds for pain, itch and mast cell-mediated hypersensitivity.

The heart of appendicularians has evolved by 'deconstructing' an ancestral ascidian-like gene regulatory network.

Chemical experiments on californium are stymied by isotope availability and radioactivity considerations, but are advanced here with synthesis and characterization of an organometallic complex.

Two-dimensional transition metal dichalcogenide diodes with defect-free van der Waals contacts allows minimization of the extrinsic interfacial disorder-dominated recombination and access to the intrinsic excitonic behaviour in two-dimensional semiconductor devices.

Cryo-electron microscopy structures of the MRGPRX2–G_i1 trimer in complex with polycationic compound 48/80 or inflammatory peptides provide insights into the sensing of cationic allergens by MRGPRX2, potentially facilitating the design of therapies to prevent unwanted pseudoallergic reactions.