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Book Review |
Vaccines — lessons from three centuries of protest
Immunization has always been a proxy for wider fears about social control, a history reminds us. By Julie Leask
- Julie Leask
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News |
The US National Academy of Sciences can now kick out harassers. So why hasn’t it?
The NAS told Nature that no one has used the complaint system put in place last year, even though several academy members are known sexual harassers.
- Giuliana Viglione
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News |
Censored: Australian scientists say suppression of environment research is getting worse
Survey finds that many researchers are banned from speaking about their work or have had their research altered to downplay risks.
- Dyani Lewis
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News |
Israel–Arab peace accord fuels hope for surge in scientific collaboration
Space, water, food security and archaeology present opportunities for joint research as United Arab Emirates and Bahrain end boycott of Israel.
- Elizabeth Gibney
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Article |
Near-perfect photon utilization in an air-bridge thermophotovoltaic cell
An air gap embedded within the structure of a thermophotovoltaic device acts as a near-perfect reflector of low-energy photons, resulting in their recovery and recycling by the thermal source, enabling excellent power-conversion efficiency.
- Dejiu Fan
- , Tobias Burger
- , Sean McSherry
- , Byungjun Lee
- , Andrej Lenert
- & Stephen R. Forrest
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News |
COVID research updates: Business-class passenger spreads coronavirus on flight
Nature wades through the literature on the new coronavirus — and summarizes key papers as they appear.
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Nature Index |
A guide to the Nature Index
A description of the terminology and methodology used in this supplement, and a guide to the functionality available free online at natureindex.com.
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Nature Index |
The top cities for research in the Nature Index
A look at the inputs that result in high scientific research outputs.
- Catherine Armitage
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Nature Index |
New York and Boston maintain their lead
The two US cities have a peerless partnership for life sciences.
- Neil Savage
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Nature Index |
Nature Index’s top five science cities, by the numbers
Sizing up the success of the world’s science hotspots.
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Nature Index |
Science cities seek new connections
In a commentary on high-impact research outputs across 245 cities, György Csomós, Zsófia Viktória Vida and Balázs Lengyel explore changing patterns.
- György Csomós
- , Zsófia Viktória Vida
- & Balázs Lengyel
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Nature Index |
Beijing, the seat of science capital
China’s powerhouse holds firm as the number one city in the Nature Index.
- Hepeng Jia
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Addendum |
Editorial Expression of Concern: Living annulative π-extension polymerization for graphene nanoribbon synthesis
- Yuuta Yano
- , Nobuhiko Mitoma
- , Kaho Matsushima
- , Feijiu Wang
- , Keisuke Matsui
- , Akira Takakura
- , Yuhei Miyauchi
- , Hideto Ito
- & Kenichiro Itami
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Author Correction |
Author Correction: Coupling dinitrogen and hydrocarbons through aryl migration
- Sean F. McWilliams
- , Daniël L. J. Broere
- , Connor J. V. Halliday
- , Samuel M. Bhutto
- , Brandon Q. Mercado
- & Patrick L. Holland
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News |
Microscopy illuminates charcoal’s sketchy origins
A large volume of charcoal sold in Europe comes from tropical forests and is often incorrectly labelled, raising questions about whether it was logged illegally.
- Aisling Irwin
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Nature Briefing |
Daily briefing: Genes map how the Vikings spread across Europe
Genetics reveals which Vikings went where during the influential Viking Age. Plus, how to get a COVID-19 vaccine to those who need it most and what happens when you read a paper every single day.
- Flora Graham
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Article |
Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion
- Donald J. Benton
- , Antoni G. Wrobel
- , Pengqi Xu
- , Chloë Roustan
- , Stephen R. Martin
- , Peter B. Rosenthal
- , John J. Skehel
- & Steven J. Gamblin
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Research Highlight |
How the giant stinging tree of Australia can inflict months of agony
A new type of peptide produces pain so intense that sometimes even morphine cannot quell it.
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Nature Briefing |
Daily briefing: We still don’t fully understand fire
Despite our intimate familiarity with fire, we still struggle with a complete understanding of it. Plus, fast antigen coronavirus tests and increasingly impenetrable papers.
- Flora Graham
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News |
Who gets a COVID vaccine first? Access plans are taking shape
Advisory groups around the world release guidance to prioritize health-care workers and those in front-line jobs.
- Nidhi Subbaraman
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Author Correction |
Author Correction: Molecular architecture of lineage allocation and tissue organization in early mouse embryo
- Guangdun Peng
- , Shengbao Suo
- , Guizhong Cui
- , Fang Yu
- , Ran Wang
- , Jun Chen
- , Shirui Chen
- , Zhiwen Liu
- , Guoyu Chen
- , Yun Qian
- , Patrick P. L. Tam
- , Jing-Dong J. Han
- & Naihe Jing
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Article |
Prokaryotic viperins produce diverse antiviral molecules
- Aude Bernheim
- , Adi Millman
- , Gal Ofir
- , Gilad Meitav
- , Carmel Avraham
- , Helena Shomar
- , Masha M. Rosenberg
- , Nir Tal
- , Sarah Melamed
- , Gil Amitai
- & Rotem Sorek
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Research Highlight |
Fleece garments are cosy — but pollute land as well as water
Many plastic microfibres filtered out of waste water end up in landfills and at other terrestrial sites.
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Nature Podcast |
Genes chart Vikings’ spread across Europe
Mapping the migration of the Vikings, and the world’s smallest ultrasound device.
- Benjamin Thompson
- & Nick Howe
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Matters Arising |
Slow compression of crystalline ice at low temperature
- R. Bauer
- , J. S. Tse
- , K. Komatsu
- , S. Machida
- & T. Hattori
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Article |
Plasmonic enhancement of stability and brightness in organic light-emitting devices
Plasmonic effects in organic light-emitting devices, which are normally considered a source of energy loss, are harnessed to enhance the stability of these devices while maintaining operational efficiency.
- Michael A. Fusella
- , Renata Saramak
- , Rezlind Bushati
- , Vinod M. Menon
- , Michael S. Weaver
- , Nicholas J. Thompson
- & Julia J. Brown
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Editorial |
A pandemic is no time to cut the European Research Council’s funding
Europe’s flagship science agency will be crucial to a post-coronavirus world. Slashing its budget will be a senseless act.
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News Round-Up |
Parenting brain switch, vanishing journals and COVID-19 in kids
The latest science news, in brief.
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News & Views |
The brain rhythms that detach us from reality
The rhythmic activity of a single layer of neurons has now been shown to cause dissociation — an experience involving a feeling of disconnection from the surrounding world.
- Ken Solt
- & Oluwaseun Akeju
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News & Views |
Planet discovered transiting a dead star
Evidence has been found of a planet circling the smouldering remains of a dead star in a tight orbit. The discovery raises the question of how the planet survived the star’s death throes — and whether other planets also orbit the remains.
- Steven Parsons
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News Feature |
Fast coronavirus tests: what they can and can’t do
Rapid antigen tests are designed to tell in a few minutes whether someone is infectious. Will they be game changers?
- Giorgia Guglielmi
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Comment |
Scientists use big data to sway elections and predict riots — welcome to the 1960s
A cold-war-era corporation targeted voters and presaged many of today’s big-data controversies.
- Jill Lepore
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Nature Briefing |
Daily briefing: World fails to meet every UN biodiversity goal
We have not met any of the 20 Aichi Biodiversity Targets agreed in 2010 — but there are hopeful signs to build on. Plus, how COVID-19 can damage the brain and a visually sumptuous tour of the latest dinosaur discoveries.
- Flora Graham
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News & Views |
Both naive and memory B cells respond to flu vaccine
Influenza vaccination induces a protective memory immune response. The finding that human naive and memory B cells enter vaccine-induced germinal-centre structures suggests that both cell types aid this memory response.
- Lauren B. Rodda
- & Marion Pepper
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Review Article |
Array programming with NumPy
NumPy is the primary array programming library for Python; here its fundamental concepts are reviewed and its evolution into a flexible interoperability layer between increasingly specialized computational libraries is discussed.
- Charles R. Harris
- , K. Jarrod Millman
- , Stéfan J. van der Walt
- , Ralf Gommers
- , Pauli Virtanen
- , David Cournapeau
- , Eric Wieser
- , Julian Taylor
- , Sebastian Berg
- , Nathaniel J. Smith
- , Robert Kern
- , Matti Picus
- , Stephan Hoyer
- , Marten H. van Kerkwijk
- , Matthew Brett
- , Allan Haldane
- , Jaime Fernández del Río
- , Mark Wiebe
- , Pearu Peterson
- , Pierre Gérard-Marchant
- , Kevin Sheppard
- , Tyler Reddy
- , Warren Weckesser
- , Hameer Abbasi
- , Christoph Gohlke
- & Travis E. Oliphant
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Article |
Homeostatic mini-intestines through scaffold-guided organoid morphogenesis
Miniature gut tubes grown in vitro from mouse intestinal stem cells are perfusable, can be colonized with microorganisms and exhibit a similar arrangement and diversity of specialized cell types to intestines in vivo.
- Mikhail Nikolaev
- , Olga Mitrofanova
- , Nicolas Broguiere
- , Sara Geraldo
- , Devanjali Dutta
- , Yoji Tabata
- , Bilge Elci
- , Nathalie Brandenberg
- , Irina Kolotuev
- , Nikolce Gjorevski
- , Hans Clevers
- & Matthias P. Lutolf
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Article |
Deep posteromedial cortical rhythm in dissociation
Dissociative states in mouse and human brains are traced to low-frequency rhythmic neural activity—with distinct molecular, cellular and physiological properties—in the deep retrosplenial cortex and the posteromedial cortex.
- Sam Vesuna
- , Isaac V. Kauvar
- , Ethan Richman
- , Felicity Gore
- , Tomiko Oskotsky
- , Clara Sava-Segal
- , Liqun Luo
- , Robert C. Malenka
- , Jaimie M. Henderson
- , Paul Nuyujukian
- , Josef Parvizi
- & Karl Deisseroth
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Article |
Population genomics of the Viking world
Ancient DNA analyses reveal that Viking Age migrations from Scandinavia resulted in differential influxes of ancestry to different parts of Europe, and the increased presence of non-local ancestry within Scandinavia.
- Ashot Margaryan
- , Daniel J. Lawson
- , Martin Sikora
- , Fernando Racimo
- , Simon Rasmussen
- , Ida Moltke
- , Lara M. Cassidy
- , Emil Jørsboe
- , Andrés Ingason
- , Mikkel W. Pedersen
- , Thorfinn Korneliussen
- , Helene Wilhelmson
- , Magdalena M. Buś
- , Peter de Barros Damgaard
- , Rui Martiniano
- , Gabriel Renaud
- , Claude Bhérer
- , J. Víctor Moreno-Mayar
- , Anna K. Fotakis
- , Marie Allen
- , Raili Allmäe
- , Martyna Molak
- , Enrico Cappellini
- , Gabriele Scorrano
- , Hugh McColl
- , Alexandra Buzhilova
- , Allison Fox
- , Anders Albrechtsen
- , Berit Schütz
- , Birgitte Skar
- , Caroline Arcini
- , Ceri Falys
- , Charlotte Hedenstierna Jonson
- , Dariusz Błaszczyk
- , Denis Pezhemsky
- , Gordon Turner-Walker
- , Hildur Gestsdóttir
- , Inge Lundstrøm
- , Ingrid Gustin
- , Ingrid Mainland
- , Inna Potekhina
- , Italo M. Muntoni
- , Jade Cheng
- , Jesper Stenderup
- , Jilong Ma
- , Julie Gibson
- , Jüri Peets
- , Jörgen Gustafsson
- , Katrine H. Iversen
- , Linzi Simpson
- , Lisa Strand
- , Louise Loe
- , Maeve Sikora
- , Marek Florek
- , Maria Vretemark
- , Mark Redknap
- , Monika Bajka
- , Tamara Pushkina
- , Morten Søvsø
- , Natalia Grigoreva
- , Tom Christensen
- , Ole Kastholm
- , Otto Uldum
- , Pasquale Favia
- , Per Holck
- , Sabine Sten
- , Símun V. Arge
- , Sturla Ellingvåg
- , Vayacheslav Moiseyev
- , Wiesław Bogdanowicz
- , Yvonne Magnusson
- , Ludovic Orlando
- , Peter Pentz
- , Mads Dengsø Jessen
- , Anne Pedersen
- , Mark Collard
- , Daniel G. Bradley
- , Marie Louise Jørkov
- , Jette Arneborg
- , Niels Lynnerup
- , Neil Price
- , M. Thomas P. Gilbert
- , Morten E. Allentoft
- , Jan Bill
- , Søren M. Sindbæk
- , Lotte Hedeager
- , Kristian Kristiansen
- , Rasmus Nielsen
- , Thomas Werge
- & Eske Willerslev
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Article |
Reprogramming roadmap reveals route to human induced trophoblast stem cells
Single-cell transcriptomics roadmap of human dermal fibroblasts reprogrammed to primed and naive pluripotency reveals a route for the direct reprogramming of somatic cells into induced trophoblast stem cells.
- Xiaodong Liu
- , John F. Ouyang
- , Fernando J. Rossello
- , Jia Ping Tan
- , Kathryn C. Davidson
- , Daniela S. Valdes
- , Jan Schröder
- , Yu B. Y. Sun
- , Joseph Chen
- , Anja S. Knaupp
- , Guizhi Sun
- , Hun S. Chy
- , Ziyi Huang
- , Jahnvi Pflueger
- , Jaber Firas
- , Vincent Tano
- , Sam Buckberry
- , Jacob M. Paynter
- , Michael R. Larcombe
- , Daniel Poppe
- , Xin Yi Choo
- , Carmel M. O’Brien
- , William A. Pastor
- , Di Chen
- , Anna L. Leichter
- , Haroon Naeem
- , Pratibha Tripathi
- , Partha P. Das
- , Alexandra Grubman
- , David R. Powell
- , Andrew L. Laslett
- , Laurent David
- , Susan K. Nilsson
- , Amander T. Clark
- , Ryan Lister
- , Christian M. Nefzger
- , Luciano G. Martelotto
- , Owen J. L. Rackham
- & Jose M. Polo
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Article |
Metabolic trait diversity shapes marine biogeography
A tight coupling between metabolic rate, efficacy of oxygen supply and the temperature sensitivities of marine animals predicts a variety of geographical niches that better aligns with the distributions of species than models of either temperature or oxygen alone.
- Curtis Deutsch
- , Justin L. Penn
- & Brad Seibel
-
Article |
A submicrometre silicon-on-insulator resonator for ultrasound detection
The widely available silicon-on-insulator technology is used to develop a miniaturized ultrasound detector, which is 200 times smaller than the wavelengths of sound that it can detect.
- Rami Shnaiderman
- , Georg Wissmeyer
- , Okan Ülgen
- , Qutaiba Mustafa
- , Andriy Chmyrov
- & Vasilis Ntziachristos
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Article |
Bridging of DNA breaks activates PARP2–HPF1 to modify chromatin
The PARP2–HPF1 histone-modifying complex bridges two nucleosomes to align broken DNA ends for ligation, initiating conformational changes that activate PARP2 and enable DNA damage repair.
- Silvija Bilokapic
- , Marcin J. Suskiewicz
- , Ivan Ahel
- & Mario Halic
-
Article |
Plasticity of ether lipids promotes ferroptosis susceptibility and evasion
The cellular organelles peroxisomes contribute to the sensitivity of cells to ferroptosis by synthesizing polyunsaturated ether phospholipids, and changes in the abundances of these lipids are associated with altered sensitivity to ferroptosis during cell-state transitions.
- Yilong Zou
- , Whitney S. Henry
- , Emily L. Ricq
- , Emily T. Graham
- , Vaishnavi V. Phadnis
- , Pema Maretich
- , Sateja Paradkar
- , Natalie Boehnke
- , Amy A. Deik
- , Ferenc Reinhardt
- , John K. Eaton
- , Bryan Ferguson
- , Wenyu Wang
- , Joshua Fairman
- , Heather R. Keys
- , Vlado Dančík
- , Clary B. Clish
- , Paul A. Clemons
- , Paula T. Hammond
- , Laurie A. Boyer
- , Robert A. Weinberg
- & Stuart L. Schreiber
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Article |
Stimulus-specific hypothalamic encoding of a persistent defensive state
Persistent neural activity in the mouse hypothalamus encodes aversive emotional states related to specific threatening stimuli.
- Ann Kennedy
- , Prabhat S. Kunwar
- , Ling-yun Li
- , Stefanos Stagkourakis
- , Daniel A. Wagenaar
- & David J. Anderson
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Article |
The superconducting quasicharge qubit
A fundamental superconducting qubit is introduced: ‘blochnium’ is dual to the transmon, relies on a circuit element called hyperinductance, and its fundamental physical variable is the quasicharge of the Josephson junction.
- Ivan V. Pechenezhskiy
- , Raymond A. Mencia
- , Long B. Nguyen
- , Yen-Hsiang Lin
- & Vladimir E. Manucharyan
-
Article |
Reverse and forward engineering of Drosophila corneal nanocoatings
The building blocks of the nanostructures observed on Drosophila corneas are determined, and then used to create artificial nanostructures with anti-reflective and anti-adhesive properties.
- Mikhail Kryuchkov
- , Oleksii Bilousov
- , Jannis Lehmann
- , Manfred Fiebig
- & Vladimir L. Katanaev
-
Article |
Red blood cell tension protects against severe malaria in the Dantu blood group
The rare blood group Dantu is known to protect against severe malaria, and a mechanism is proposed here: Dantu red blood cells have a high membrane tension that prevents invasion by malaria parasites.
- Silvia N. Kariuki
- , Alejandro Marin-Menendez
- , Viola Introini
- , Benjamin J. Ravenhill
- , Yen-Chun Lin
- , Alex Macharia
- , Johnstone Makale
- , Metrine Tendwa
- , Wilfred Nyamu
- , Jurij Kotar
- , Manuela Carrasquilla
- , J. Alexandra Rowe
- , Kirk Rockett
- , Dominic Kwiatkowski
- , Michael P. Weekes
- , Pietro Cicuta
- , Thomas N. Williams
- & Julian C. Rayner
-
Article |
A giant planet candidate transiting a white dwarf
A giant planet candidate roughly the size of Jupiter but more than 14 times as massive is observed by TESS and other instruments to be transiting the white dwarf star WD 1856+534.
- Andrew Vanderburg
- , Saul A. Rappaport
- , Siyi Xu
- , Ian J. M. Crossfield
- , Juliette C. Becker
- , Bruce Gary
- , Felipe Murgas
- , Simon Blouin
- , Thomas G. Kaye
- , Enric Palle
- , Carl Melis
- , Brett M. Morris
- , Laura Kreidberg
- , Varoujan Gorjian
- , Caroline V. Morley
- , Andrew W. Mann
- , Hannu Parviainen
- , Logan A. Pearce
- , Elisabeth R. Newton
- , Andreia Carrillo
- , Ben Zuckerman
- , Lorne Nelson
- , Greg Zeimann
- , Warren R. Brown
- , René Tronsgaard
- , Beth Klein
- , George R. Ricker
- , Roland K. Vanderspek
- , David W. Latham
- , Sara Seager
- , Joshua N. Winn
- , Jon M. Jenkins
- , Fred C. Adams
- , Björn Benneke
- , David Berardo
- , Lars A. Buchhave
- , Douglas A. Caldwell
- , Jessie L. Christiansen
- , Karen A. Collins
- , Knicole D. Colón
- , Tansu Daylan
- , John Doty
- , Alexandra E. Doyle
- , Diana Dragomir
- , Courtney Dressing
- , Patrick Dufour
- , Akihiko Fukui
- , Ana Glidden
- , Natalia M. Guerrero
- , Xueying Guo
- , Kevin Heng
- , Andreea I. Henriksen
- , Chelsea X. Huang
- , Lisa Kaltenegger
- , Stephen R. Kane
- , John A. Lewis
- , Jack J. Lissauer
- , Farisa Morales
- , Norio Narita
- , Joshua Pepper
- , Mark E. Rose
- , Jeffrey C. Smith
- , Keivan G. Stassun
- & Liang Yu