Browse Articles

Filters ​

  • Career Feature |

    As COVID-19 restrictions continue to upend plans for data collection, scientists stuck at home are finding innovative ways to adapt their research questions. Here’s what they’re doing.

    • Nikki Forrester

  • Nature Index |

    A description of the terminology and methodology used in this supplement, and a guide to the functionality available free online at natureindex.com.

  • Outlook |

    Advances in treatment and a better understanding of the cancer mean people with the disease are living longer.

    • Brian Owens

  • News & Views |

    The first detection of neutrinos produced by the Sun’s secondary solar-fusion cycle paves the way for a detailed understanding of the structure of the Sun and of the formation of massive stars.

    • Gabriel D. Orebi Gann

  • Outlook |

    Treatments that help the immune system fight multiple myeloma are emerging fast, but the number of people who relapse remains.

    • Dalmeet Singh Chawla

  • Nature Index |

    With record levels of funding, German start-ups are building the nation’s strength in innovation.

    • Gemma Conroy
    • , Natalie Parletta
    •  & Chris Woolston

  • News & Views |

    The fossil record traces the origin of the modern bird skull as birds evolved from their dinosaurian ancestors. Now the discovery of a bizarre fossil reveals a surprising diversion during this process of facial transformation.

    • Daniel J. Field

  • News Feature |

    The tiny island nation brought huge scientific heft to its attempts to contain and study the coronavirus. Here’s what it learnt.

    • Megan Scudellari

  • Outlook |

    Immunotherapy that targets a hair-follicle protein, genetic changes that underlie disease development and other highlights from clinical trials and laboratory studies.

    • Jyoti Madhusoodanan

  • Article |

    • Ameen A. Salahudeen
    • , Shannon S. Choi
    • , Arjun Rustagi
    • , Junjie Zhu
    • , Vincent van Unen
    • , Sean M. de la O
    • , Ryan A. Flynn
    • , Mar Margalef-Català
    • , António J. M. Santos
    • , Jihang Ju
    • , Arpit Batish
    • , Tatsuya Usui
    • , Grace X. Y. Zheng
    • , Caitlin E. Edwards
    • , Lisa E. Wagar
    • , Vincent Luca
    • , Benedict Anchang
    • , Monica Nagendran
    • , Khanh Nguyen
    • , Daniel J. Hart
    • , Jessica M. Terry
    • , Phillip Belgrader
    • , Solongo B. Ziraldo
    • , Tarjei S. Mikkelsen
    • , Pehr B. Harbury
    • , Jeffrey S. Glenn
    • , K. Christopher Garcia
    • , Mark M. Davis
    • , Ralph S. Baric
    • , Chiara Sabatti
    • , Manuel R. Amieva
    • , Catherine A. Blish
    • , Tushar J. Desai
    •  & Calvin J. Kuo

  • Article |

    Direct experimental evidence of the carbon–nitrogen–oxygen fusion cycle in the Sun is provided by the detection of neutrinos emitted during this process.

    • M. Agostini
    • , K. Altenmüller
    • , S. Appel
    • , V. Atroshchenko
    • , Z. Bagdasarian
    • , D. Basilico
    • , G. Bellini
    • , J. Benziger
    • , R. Biondi
    • , D. Bravo
    • , B. Caccianiga
    • , F. Calaprice
    • , A. Caminata
    • , P. Cavalcante
    • , A. Chepurnov
    • , D. D’Angelo
    • , S. Davini
    • , A. Derbin
    • , A. Di Giacinto
    • , V. Di Marcello
    • , X. F. Ding
    • , A. Di Ludovico
    • , L. Di Noto
    • , I. Drachnev
    • , A. Formozov
    • , D. Franco
    • , C. Galbiati
    • , C. Ghiano
    • , M. Giammarchi
    • , A. Goretti
    • , A. S. Göttel
    • , M. Gromov
    • , D. Guffanti
    • , Aldo Ianni
    • , Andrea Ianni
    • , A. Jany
    • , D. Jeschke
    • , V. Kobychev
    • , G. Korga
    • , S. Kumaran
    • , M. Laubenstein
    • , E. Litvinovich
    • , P. Lombardi
    • , I. Lomskaya
    • , L. Ludhova
    • , G. Lukyanchenko
    • , L. Lukyanchenko
    • , I. Machulin
    • , J. Martyn
    • , E. Meroni
    • , M. Meyer
    • , L. Miramonti
    • , M. Misiaszek
    • , V. Muratova
    • , B. Neumair
    • , M. Nieslony
    • , R. Nugmanov
    • , L. Oberauer
    • , V. Orekhov
    • , F. Ortica
    • , M. Pallavicini
    • , L. Papp
    • , L. Pelicci
    • , Ö. Penek
    • , L. Pietrofaccia
    • , N. Pilipenko
    • , A. Pocar
    • , G. Raikov
    • , M. T. Ranalli
    • , G. Ranucci
    • , A. Razeto
    • , A. Re
    • , M. Redchuk
    • , A. Romani
    • , N. Rossi
    • , S. Schönert
    • , D. Semenov
    • , G. Settanta
    • , M. Skorokhvatov
    • , A. Singhal
    • , O. Smirnov
    • , A. Sotnikov
    • , Y. Suvorov
    • , R. Tartaglia
    • , G. Testera
    • , J. Thurn
    • , E. Unzhakov
    • , F. L. Villante
    • , A. Vishneva
    • , R. B. Vogelaar
    • , F. von Feilitzsch
    • , M. Wojcik
    • , M. Wurm
    • , S. Zavatarelli
    • , K. Zuber
    •  & G. Zuzel

  • Article |

    Depletion of TRF2—an essential mediator of telomere protection in most mammalian cells—in mouse embryonic stem cells activates a compensatory transcriptional program that renders TRF2 dispensable for their survival and proliferation.

    • Marta Markiewicz-Potoczny
    • , Anastasia Lobanova
    • , Anisha M. Loeb
    • , Oktay Kirak
    • , Teresa Olbrich
    • , Sergio Ruiz
    •  & Eros Lazzerini Denchi

  • Article |

    Chromosome-scale sequence assemblies of 20 diverse varieties of barley are used to construct a first-generation pan-genome, revealing previously hidden genetic variation that can be used by studies aimed at crop improvement

    • Murukarthick Jayakodi
    • , Sudharsan Padmarasu
    • , Georg Haberer
    • , Venkata Suresh Bonthala
    • , Heidrun Gundlach
    • , Cécile Monat
    • , Thomas Lux
    • , Nadia Kamal
    • , Daniel Lang
    • , Axel Himmelbach
    • , Jennifer Ens
    • , Xiao-Qi Zhang
    • , Tefera T. Angessa
    • , Gaofeng Zhou
    • , Cong Tan
    • , Camilla Hill
    • , Penghao Wang
    • , Miriam Schreiber
    • , Lori B. Boston
    • , Christopher Plott
    • , Jerry Jenkins
    • , Yu Guo
    • , Anne Fiebig
    • , Hikmet Budak
    • , Dongdong Xu
    • , Jing Zhang
    • , Chunchao Wang
    • , Jane Grimwood
    • , Jeremy Schmutz
    • , Ganggang Guo
    • , Guoping Zhang
    • , Keiichi Mochida
    • , Takashi Hirayama
    • , Kazuhiro Sato
    • , Kenneth J. Chalmers
    • , Peter Langridge
    • , Robbie Waugh
    • , Curtis J. Pozniak
    • , Uwe Scholz
    • , Klaus F. X. Mayer
    • , Manuel Spannagl
    • , Chengdao Li
    • , Martin Mascher
    •  & Nils Stein

  • Article |

    Optically dark (non-emitting) triplet excitons on organic molecules may be rendered bright by coupling the molecules to lanthanide-doped nanoparticles, providing a way to control such excitons in optoelectronic systems.

    • Sanyang Han
    • , Renren Deng
    • , Qifei Gu
    • , Limeng Ni
    • , Uyen Huynh
    • , Jiangbin Zhang
    • , Zhigao Yi
    • , Baodan Zhao
    • , Hiroyuki Tamura
    • , Anton Pershin
    • , Hui Xu
    • , Zhiyuan Huang
    • , Shahab Ahmad
    • , Mojtaba Abdi-Jalebi
    • , Aditya Sadhanala
    • , Ming Lee Tang
    • , Artem Bakulin
    • , David Beljonne
    • , Xiaogang Liu
    •  & Akshay Rao

  • Article |

    Experiments in mouse pluripotent embryonic and epiblast stem cells show that TRF2 is dispensable for telomere protection specifically specifically in the pluripotent cells that form during early embryonic development, when cells form T-loops independently of this protein.

    • Phil Ruis
    • , David Van Ly
    • , Valerie Borel
    • , Georgia R. Kafer
    • , Afshan McCarthy
    • , Steven Howell
    • , Robert Blassberg
    • , Ambrosius P. Snijders
    • , James Briscoe
    • , Kathy K. Niakan
    • , Paulina Marzec
    • , Anthony J. Cesare
    •  & Simon J. Boulton

  • Review Article |

    This review discusses how single-cell profiling and other technological advances are increasing our understanding of the mechanisms of fibrosis, thereby accelerating the discovery, development and testing of new treatments.

    • Neil C. Henderson
    • , Florian Rieder
    •  & Thomas A. Wynn

  • Article |

    Changes in Northern Hemisphere ice-sheet size during ice-age cycles enhance the advance and retreat of the grounding line of the Antarctic Ice Sheet, owing to interhemispheric sea-level forcing.

    • Natalya Gomez
    • , Michael E. Weber
    • , Peter U. Clark
    • , Jerry X. Mitrovica
    •  & Holly K. Han

  • Article |

    Influence of the gut microbiome on the human immune system is revealed by systems analysis of vast clinical data from decades of electronic health records paired with massive longitudinal microbiome sequencing.

    • Jonas Schluter
    • , Jonathan U. Peled
    • , Bradford P. Taylor
    • , Kate A. Markey
    • , Melody Smith
    • , Ying Taur
    • , Rene Niehus
    • , Anna Staffas
    • , Anqi Dai
    • , Emily Fontana
    • , Luigi A. Amoretti
    • , Roberta J. Wright
    • , Sejal Morjaria
    • , Maly Fenelus
    • , Melissa S. Pessin
    • , Nelson J. Chao
    • , Meagan Lew
    • , Lauren Bohannon
    • , Amy Bush
    • , Anthony D. Sung
    • , Tobias M. Hohl
    • , Miguel-Angel Perales
    • , Marcel R. M. van den Brink
    •  & Joao B. Xavier

  • Article |

    Analysis of humeri from fossils that span the fin-to-limb transition reveal that the change in the humerus shape is driven by both ecology and phylogeny, and is associated with functional trade-offs related to locomotor performance.

    • Blake V. Dickson
    • , Jennifer A. Clack
    • , Timothy R. Smithson
    •  & Stephanie E. Pierce

  • Article |

    A comprehensive map of transcriptomes, cis-regulatory elements, heterochromatin structure, the methylome and 3D genome organization in the zebrafish (Danio rerio) enables identification of species-specific and evolutionarily conserved regulatory features, and provides a foundation for modelling studies on human disease and development.

    • Hongbo Yang
    • , Yu Luan
    • , Tingting Liu
    • , Hyung Joo Lee
    • , Li Fang
    • , Yanli Wang
    • , Xiaotao Wang
    • , Bo Zhang
    • , Qiushi Jin
    • , Khai Chung Ang
    • , Xiaoyun Xing
    • , Juan Wang
    • , Jie Xu
    • , Fan Song
    • , Iyyanki Sriranga
    • , Chachrit Khunsriraksakul
    • , Tarik Salameh
    • , Daofeng Li
    • , Mayank N. K. Choudhary
    • , Jacek Topczewski
    • , Kai Wang
    • , Glenn S. Gerhard
    • , Ross C. Hardison
    • , Ting Wang
    • , Keith C. Cheng
    •  & Feng Yue