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In a worst-case scenario, the pandemic could cause a further 300,000 deaths if anti-contagion policies are lifted and people revert to their old habits.
A description of the terminology and methodology used in this supplement, and a guide to the functionality that is available free online at natureindex.com.
The successful in-orbit operation of an electric space propulsion system based on iodine, rather than the more expensive and difficult-to-store xenon, is demonstrated.
A new technique called immunoGAM, which combines genome architecture mapping (GAM) with immunoselection, enabled the discovery of specialized chromatin conformations linked to gene expression in specific cell populations from mouse brain tissues.
Structural studies of the itch receptors MRGPRX2 and MRGPRX4 in complex with endogenous and synthetic ligands provide a basis for the development of therapeutic compounds for pain, itch and mast cell-mediated hypersensitivity.
Chemical experiments on californium are stymied by isotope availability and radioactivity considerations, but are advanced here with synthesis and characterization of an organometallic complex.
Two-dimensional transition metal dichalcogenide diodes with defect-free van der Waals contacts allows minimization of the extrinsic interfacial disorder-dominated recombination and access to the intrinsic excitonic behaviour in two-dimensional semiconductor devices.
Cryo-electron microscopy structures of the MRGPRX2–Gi1 trimer in complex with polycationic compound 48/80 or inflammatory peptides provide insights into the sensing of cationic allergens by MRGPRX2, potentially facilitating the design of therapies to prevent unwanted pseudoallergic reactions.
A study demonstrates that a range of different behaviours—from reversible, through weeping, to explosive—can be exhibited by a chemically homogeneous ceramic system by manipulating conditions of compatibility in unusual ways.
Activity in anterior deep cerebellar nuclei reduces food consumption in mice without reducing metabolic rate, potentially identifying a therapeutic target for disorders involving excessive eating.
Genetic manipulation of skin peripheral sensory neurons in mice shows that cortical neuron responses to touch reflect subcortical mixing of signals from both rapidly adapting and slowly adapting low-threshold mechanoreceptors.
Data collected from crisis helplines during the COVID-19 pandemic show that pandemic-related issues replaced rather than exacerbated underlying anxieties, and demonstrate that helpline data are useful indicators of public mental health.
Herpes simplex virus type I and pseudorabies virus assimilate kinesin from host epithelial cells and repurpose the motor to traffic to the nuclei of neurons in the peripheral nervous system.
Experiments with a trapped-ion quantum simulator observe Stark many-body localization, in which the quantum system evades thermalization despite having no disorder.