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A new strategy to separate radioactive americium from lanthanides based on complexation with polyoxometalates and ultrafiltration technique is highly efficient and rapid, does not involve any organic components and requires minimal energy input.
A depolymerization method is described that uses electrified spatiotemporal heating to selectively generate monomers from the commodity plastics polypropylene and poly(ethylene terephthalate), allowing control over the pyrolysis of plastic waste and reducing the formation of side products.
Using single-molecule imaging, the authors show that Smc5/6 forms DNA loops by extrusion, which establishes DNA loop extrusion as a conserved mechanism among eukaryotic SMC complexes.
Using a quantum annealing processor to study three-dimensional spin glasses demonstrates an accurate large-scale quantum simulation of critical dynamics and a scaling advantage over analogous classical methods for energy optimization.
The authors develop a new oxide-dispersion-strengthened NiCoCr-based alloy using a model-driven alloy design approach and laser-based additive manufacturing, showing how such designs can provide superior compositions using far fewer resources than previous methods.
Cryo-electron microscopy structures reveal how XPC recognizes DNA lesions and recruits XPA and the TFIIH core complex for lesion verification in nucleotide excision repair.
CTCF is sufficient to block loop extruding cohesin in a DNA tension dependent manner, and induces loop extrusion direction switching and loop shrinkage.
A study shows that, although the number of incarcerated people in the USA decreased during the first year of the COVID-19 pandemic, the fraction of incarcerated Black and Latino individuals increased.
A mouse model of invasive breast cancer in which Pten and Trp53 are simultaneously inactivated links PTEN loss with STAT3 activation and indicates that immune escape in PTEN-null tumours is mediated by PI3Kβ.
Functional MRI studies across ages show that the classic homunculus of the motor cortex in humans is in fact discontinuous, alternating with action control-linked regions termed the somato-cognitive action network.
Arabidopsis thaliana UMAMIT uniporters facilitate glucosinolate efflux from biosynthetic cells along the electrochemical gradient into the apoplast, in which the high-affinity H+-coupled glucosinolate importers GLUCOSINOLATE TRANSPORTERS (GTRs) load them into the phloem for translocation to the seeds.
We demonstrate the memory effects and stimuli-regulated transport of molecules through an intelligent, phase-changing MoS2 membrane in response to external pH, a phenomenon unique to the 1T′ phase of MoS2.
A phylogeny-guided genome-resolved metagenomic analysis of DNA viruses in the ocean reveals atypical plankton-infecting relatives of herpesviruses that form a putative new phylum dubbed Mirusviricota.
Local microenvironmental cues modulate melanocyte stem cells, which control hair pigmentation, to enter different differentiation states, shifting between hair follicle stem cell and transit-amplifying compartments, a process that is different to other self-renewing systems.
The ability to separate the radioactive element americium from spent nuclear fuel would lower the long-term hazards of nuclear waste. An inorganic molecular cage that selectively binds to americium opens up a separation strategy.
The observation that melanocyte stem cells migrate up and down the hair follicle, differentiating into melanocytes and then returning to a stem-cell identity, calls into question long-held assumptions about adult stem cells.