Longer-Lasting Electron-Based Microscopy of Single Molecules in Aqueous Medium
© Science Photo Library - STEVE GSCHMEISSNER/Getty
Swapping ‘heavy’ water for regular water should allow scientists to use transmission electron microscopy (TEM) to observe biological materials in water using for longer before damage occurs.
Although a powerful technology for studying molecules in dry or frozen states, the high-energy electron beams used in TEM to probe molecules in water generate an electric charge that breaks chemical bonds and damage specimens.
Now, a team of scientists at the Institute for Basic Sciences has used
The scientists found that organic molecules dissolved in D2O lasted 2 to 5 times longer than those dissolved in water.
- ACS Nano 12, 8572–8578 (2018). doi: 10.1021/acsnano.8b04190
|Center for Soft and Living Matter, IBS, South Korea||0.67|
|Ulsan National Institute of Science and Technology (UNIST), South Korea||0.33|