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In this pilot study, the authors detected specific brain regions that can be precisely targeted with transcranial magnetic stimulation to influence heart rate. The heart–brain coupling might serve as a readout to identify optimal individualized transcranial magnetic stimulation targets for depression.
The authors report data from the emergency department AURORA study to characterize resilience in more detail than the absence of psychopathology after trauma.
This study identifies a set of risk factors that fully mediate and uniquely contribute to the relationship between sex assigned at birth and posttraumatic stress disorder severity.
The authors conducted a systematic review to examine whether pharmacogenetic testing affects clinical or economic outcomes in patients taking antipsychotic medication.
Using stereotactic electroencephalography, the authors identified differential amygdala activation in response to emotional faces in participants with treatment-resistant depression compared with non-depressed participants with epilepsy, suggesting possible deep brain stimulation targets.
In this cross-species translational study, the authors look at the longitudinal consequences of stress during adolescent development on HPA function and postpartum behaviors in mice and in humans and suggest that glucocorticoid receptor antagonists may serve as a potential treatment for postpartum depression.
In this article, the authors demonstrate that haloperidol D2/D3 dopamine antagonism contributes to flexibility in beliefs about the intentions of social partners during a sharing game.
Singh and colleagues present an integrative genotypic approach using large-scale GWAS data for depression and coronary artery disease to identify genes associated with both conditions.
A study on a large cohort of military veterans of European and African ancestries finds no evidence that the APOE ε4 genotype moderates the impact of combat exposure on posttraumatic stress disorder symptom severity and diagnostic status.
Using a longitudinal structural imaging design, the authors assessed cortical anatomy and genes linked to methylphenidate activity to identify treatment-associated responses in adults with attention deficit hyperactivity disorder.
Using a large sample from the UK Biobank, the authors investigate the effects of dietary patterns on multiple aspects of brain health and mental health.
The authors examine the longitudinal relationship between residential greenness and the incidence of depression and anxiety using a sample of 409,556 participants from the UK Biobank.
Zhao, Liu et al. investigate the relationship between cognitive decline, chronic musculoskeletal pain and brain structure using an algorithm that can detect deviations from normative brain aging.
Chen et al. employed ecological momentary assessment in two different sample populations from the United States and China to develop proxy measures for emotion regulation flexibility.
The authors report an association of particulate matter air pollution with death by suicide in Finland that was particularly evident among males and during the warm season; however, the evidence for the associations by urbanicity or subperiod remained weak.
A magnetoencephalography study provides evidence that neural signal complexity declines with brain maturation in human fetuses and newborns and the decline occurs faster in male fetuses.
The authors used a large sample of trios from the MoBa cohort study to estimate direct and indirect genetic effects on maternal depression at various time points using trio-GCTA.
Physical activity has the potential to combat the negative mental health effects of social isolation. Its benefit is particularly high in people at increased neural and psychological risk for affective disorders.
The authors used a machine learning model to distinguish patients with cocaine use disorder and polysubstance use history from healthy controls, using resting-state functional magnetic resonance imaging functional connectivity data.