Articles in 2021

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  • Reflecting on 2020 brings into focus clear challenges for the year ahead, including for AI research that contemplates its broader societal impact.

    Editorial
  • Autonomous flight is challenging for small flying robots, given the limited space for sensors and on-board processing capabilities, but a promising approach is to mimic optical-flow-based strategies of flying insects. A new development improves this technique, enabling smoother landings and better obstacle avoidance, by giving robots the ability to learn to estimate distances to objects by their visual appearance.

    • G. C. H. E. de Croon
    • C. De Wagter
    • T. Seidl
    Article
  • We invited authors of selected Comments and Perspectives published in Nature Machine Intelligence in the latter half of 2019 and first half of 2020 to describe how their topic has developed, what their thoughts are about the challenges of 2020, and what they look forward to in 2021.

    • Anna Jobin
    • Kingson Man
    • Miguel Luengo-Oroz
    Feature
  • To remove artefacts from medical imaging, machine learning can be a useful tool, but supervised approaches need examples of the same image with and without artefacts. Liu et al. present a method to train an artefact removal network without needing matching images of corrupted and uncorrupted images.

    • Siyuan Liu
    • Kim-Han Thung
    • Pew-Thian Yap
    Article
  • The transcription process of DNA is highly complex and while short DNA sequence motifs recognized by transcription factors are well known, less is known about the context in the DNA sequence that determines whether a transcription factor will actually bind its motif. Zheng and colleagues present a method that uses convolutional neural networks to identify sequence features that help predict whether transcribing proteins can bind to their target sequences in DNA.

    • An Zheng
    • Michael Lamkin
    • Melissa Gymrek
    Article
  • Evolutionary computation is inspired by biological evolution and exhibits characteristics familiar from biology such as openendedness, multi-objectivity and co-evolution. This Perspective highlights where major differences still exist, and where the field of evolutionary computation could attempt to approach features from biological evolution more closely, namely neutrality and random drift, complex genotype-to-phenotype mappings with rich environmental interactions and major organizational transitions.

    • Risto Miikkulainen
    • Stephanie Forrest
    Perspective
  • Microrobotics offers great potential for precise drug delivery as medication can be released in the bloodstream only where it is needed. But the dynamic environment of the bloodstream is a challenge for navigation. An approach presented by Ahmed and colleagues combines magnetic and acoustic fields to allow swarms of particles to swim against a current.

    • Daniel Ahmed
    • Alexander Sukhov
    • Bradley J. Nelson
    Article
  • The annotation of the visual signs of emotions can be important for psychological studies and even human–computer interactions. Instead of only ascribing discrete emotions, Toisoul and colleagues use a single neural network that predicts emotional labels on a spectrum of valence and arousal without separate face-alignment steps.

    • Antoine Toisoul
    • Jean Kossaifi
    • Maja Pantic
    Article
  • Reticular frameworks are crystalline porous materials with desirable properties such as gas separation, but their large design space presents a challenge. An automated nanoporous materials discovery platform powered by a supramolecular variational autoencoder can efficiently explore this space.

    • Zhenpeng Yao
    • Benjamín Sánchez-Lengeling
    • Alán Aspuru-Guzik
    Article
  • Turbulence modelling is an essential flow simulation tool, but is typically dependent on physical insight and engineering intuition. Novati et al. develop a multi-agent reinforcement learning approach for learning turbulence models that can generalize across grid sizes and flow conditions.

    • Guido Novati
    • Hugues Lascombes de Laroussilhe
    • Petros Koumoutsakos
    Article
  • Many approved drugs can be used to treat diseases other than the one they were developed for, which has the added benefit that the safety of the drug has already been tested. To identify possible candidates for re-purposing trials, Liu et al. have developed a method to use existing electronic patient data to simulate clinical trials and identify drugs that influence the progression of diseases with which they were not previously associated.

    • Ruoqi Liu
    • Lai Wei
    • Ping Zhang
    Article