Tumour Microenvironment
Throughout 2006 and 2007, a series of articles on the Tumour Microenvironment was published in Nature Reviews Cancer. The study of the tumour microenvironment involves a multidisciplinary approach, with in vitro and in vivo models of tumour growth, invasion, extracellular matrix remodelling, angiogenesis and inflammation, as well as preclinical trials, all contributing to the rapid progress that is being made in this area. We hope that this series of articles gave you a taste of the diversity of topics that form part of this rapidly moving field.
2007
October 2007 v7 n10
Emerging roles of proteases in tumour suppression
Carlos López-Otín & Lynn M. Matrisian
doi:10.1038/nrc2228
October 2007 v7 n10
Making a tumour's bed: glioblastoma stem cells and the vascular niche
Richard J. Gilbertson & Jeremy N. Rich
doi:10.1038/nrc2246
June 2007 v7 n6
Morphogens, morphostats, microarchitecture and malignancy
John D. Potter
doi:10.1038/nrc2146
May 2007 v7 n5
Laminin 332 in squamous–cell carcinoma
M. Peter Marinkovich
doi:10.1038/nrc2089
February 2007 v7 n2
The tumour microenvironment as a target for chemoprevention
Adriana Albini and Michael B. Sporn
doi:10.1038/nrc2067
2006
October 2006 Vol 6 No 10
Cysteine cathepsins: multifunctional enzymes in cancer
Mona Mostafa Mohamed & Bonnie F. Sloane
August 2006 Vol 6 No 8
Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors
Alexander J. Muller & Peggy A. Scherle
August 2006 Vol 6 No 8
Drug penetration in solid tumours
Andrew I. Minchinton & Ian F. Tannock
July 2006 Vol 6 No 7
Tumour microenvironment: TGFβ: the molecular Jekyll and Hyde of cancer
Brian Bierie & Harold L. Moses
May 2006 Vol 6 No 5
Fibroblasts in cancer
Raghu Kalluri & Michael Zeisberg
April 2006 Vol 6 No 4
Pregnancy-associated breast cancer and metastasis
Pepper Schedin
March 2006 Vol 6 No 3
Tumour microenvironment − Opinion: Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy
Christopher M. Overall & Oded Kleifeld