The potential of evinacumab, a monoclonal antibody targeting angiopoietin-like 3, for reducing triglyceride levels was tested in patients with severe hypertriglyceridemia due to differing genetic etiologies.

A deep-learning algorithm was developed to identify skin lesions caused by the mpox virus and was then implemented in a web-based app designed for patient use.

Clinical, genomic and transcriptomic analyses of paired samples of synchronous bilateral female breast cancer identify associations between tumor concordance and immune infiltrates levels and response to neoadjuvant treatment.

Nature Medicine explores the latest translational and clinical research news, with a monoclonal antibody that blocks the transfer of maternal immunoglobulins in pregnancy.

Clinical, genomic and transcriptomic analyses of paired samples of synchronous bilateral female breast cancer identify associations between tumor concordance and immune infiltrates levels and response to neoadjuvant treatment.

In a cohort of patients with cerebral arachnoid cysts, multiomic analyses reveal de novo variants causing genetic neurodevelopmental conditions in up to 16% of cases, suggesting that surgery in these cases may not improve non-mass effect-related symptoms.

The potential of evinacumab, a monoclonal antibody targeting angiopoietin-like 3, for reducing triglyceride levels was tested in patients with severe hypertriglyceridemia due to differing genetic etiologies.

A combination of real-world evidence and a reanalysis of phase 3 clinical trial data unveils KRAS codon G12 mutations as a biomarker of resistance to trifluridine/tipiracil in metastatic colorectal cancer.

A deep-learning algorithm was developed to identify skin lesions caused by the mpox virus and was then implemented in a web-based app designed for patient use.

Neutralizing antibody titers elicited by either ancestral or bivalent COVID-19 vaccine boosters are predicted to increase protection against severe disease due to SARS-CoV-2 variants.

An MRI-guided, focused ultrasound ablation technique shows promise as a non-invasive treatment.

Existing models for predicting the 10-year risk of stroke are less accurate for Black adults than for white adults, even with the addition of novel machine-learning algorithms.

Nature Medicine explores the latest translational and clinical research news, with a monoclonal antibody that blocks the transfer of maternal immunoglobulins in pregnancy.

In patients with advanced melanoma, adherence to a habitual Mediterranean diet was associated with a higher probability of responding to immunotherapy.

Hailey, an AI feedback tool, helps online mental health support workers to respond with more empathy.

A single dose of azithromycin substantially reduced maternal sepsis and death, according to a large, international, randomized study.