Focus
Focus on Development and Disease
- Focus issue:
- September 2007 Volume 9, No 9
Much progress has been made in our understanding of the molecular mechanisms underlying animal development, uncovering numerous links with human disease pathologies.
This issue of Nature Cell Biology presents a series of specially-commissioned articles that highlights how developmental pathways gone awry can cause disease. These articles are available free until the end of February 2008.
The focus is sponsored by the March of Dimes foundation, as well as the Institute of Biochemistry and Cell Biology, Shanghai, and the Guangzhou Institute of Biomedicine and Health of the Chinese Academy of Sciences.
Editorial
Focus on Development and Disease
Developing disease - p983
doi:10.1038/ncb0907-983
Full Text - Developing disease | PDF (113 KB) - Developing disease
Commentaries
Focus on Development and Disease
Human–animal cytoplasmic hybrid embryos, mitochondria, and an energetic debate - pp988 - 992
Justin St John & Robin Lovell-Badge
doi:10.1038/ncb436
Full Text - Human–animal cytoplasmic hybrid embryos, mitochondria, and an energetic debate | PDF (318 KB) - Human–animal cytoplasmic hybrid embryos, mitochondria, and an energetic debate
Focus on Development and Disease
The mouse ascending: perspectives for human-disease models - pp993 - 999
Nadia Rosenthal & Steve Brown
doi:10.1038/ncb437
Full Text - The mouse ascending: perspectives for human-disease models | PDF (363 KB) - The mouse ascending: perspectives for human-disease models
Perspectives
Focus on Development and Disease
Differentiation plasticity regulated by TGF-
family proteins in development and disease - pp1000 - 1004
Rik Derynck & Rosemary J. Akhurst
doi:10.1038/ncb434
Full Text - Differentiation plasticity regulated by TGF- family proteins in development and disease | PDF (297 KB) - Differentiation plasticity regulated by TGF-
family proteins in development and disease
Focus on Development and Disease
Patching the gaps in Hedgehog signalling - pp1005 - 1009
Rajat Rohatgi & Matthew P. Scott
doi:10.1038/ncb435
Full Text - Patching the gaps in Hedgehog signalling | PDF (304 KB) - Patching the gaps in Hedgehog signalling
Focus on Development and Disease
Convergent extension and the hexahedral cell - pp1010 - 1015
Jeremy B. A. Green & Lance A. Davidson
doi:10.1038/ncb438
Full Text - Convergent extension and the hexahedral cell | PDF (497 KB) - Convergent extension and the hexahedral cell
Review
Focus on Development and Disease
Cell polarity in development and cancer - pp1016 - 1024
Andreas Wodarz & Inke Näthke
doi:10.1038/ncb433
Abstract - Cell polarity in development and cancer | Full Text - Cell polarity in development and cancer | PDF (528 KB) - Cell polarity in development and cancer