Scientific Reports

Collection 06 March 2024

Cancer Top 100 of 2023

This collection highlights the most downloaded* cancer research papers published by Scientific Reports in 2023. Featuring authors from around the world, these papers highlight valuable research from an international community.

You can also view the journal's overall Top 100 or the Top 100 within various subject areas.

*Data obtained from SN Insights, which is based on Digital Science’s Dimensions.

1-25

Severe SARS-CoV-2 infection as a marker of undiagnosed cancer: a population-based study
- Adeline Dugerdil
- Laura Semenzato
- Antoine Flahault
ArticleOpen Access30 May 2023 Scientific Reports
Diabetes medications and cancer risk associations: a systematic review and meta-analysis of evidence over the past 10 years
- Yixian Chen
- Fidela Mushashi
- Rachel A. Murphy
ArticleOpen Access22 Jul 2023 Scientific Reports
Classification and diagnostic prediction of breast cancer metastasis on clinical data using machine learning algorithms
- Mahendran Botlagunta
- Madhavi Devi Botlagunta
- Mohd Asif Shah
ArticleOpen Access10 Jan 2023 Scientific Reports
Non-invasive screening of breast cancer from fingertip smears—a proof of concept study
- C. Russo
- L. Wyld
- S. Francese
ArticleOpen Access1 Feb 2023 Scientific Reports
Combining machine learning with Cox models to identify predictors for incident post-menopausal breast cancer in the UK Biobank
- Xiaonan Liu
- Davide Morelli
- Lei Clifton
ArticleOpen Access7 Jun 2023 Scientific Reports
Mutational landscape of cancer-driver genes across human cancers
- Musalula Sinkala
ArticleOpen Access7 Aug 2023 Scientific Reports
Comprehensive liquid biopsy analysis as a tool for the early detection of minimal residual disease in breast cancer
- Dimitra Stergiopoulou
- Athina Markou
- Evi Lianidou
ArticleOpen Access23 Jan 2023 Scientific Reports
Diagnostic and prognostic potential of the microbiome in ovarian cancer treatment response
- Abigail E. Asangba
- Jun Chen
- Marina R. S. Walther-Antonio
ArticleOpen Access13 Jan 2023 Scientific Reports
Tumor organoid biobank-new platform for medical research
- Xuexue Xie
- Xinyu Li
- Wei Song
ArticleOpen Access1 Feb 2023 Scientific Reports
The effect of acute exercise on circulating immune cells in newly diagnosed breast cancer patients
- Tiia Koivula
- Salla Lempiäinen
- Ilkka Heinonen
ArticleOpen Access21 Apr 2023 Scientific Reports
Cancer incidence amongst UK firefighters
- Taylor A. M. Wolffe
- Andrew Robinson
- Anna A. Stec
ArticleOpen Access10 Jan 2023 Scientific Reports
The optimization of postoperative radiotherapy in de novo stage IV breast cancer: evidence from real-world data to personalize treatment decisions
- Minoru Miyashita
- Onyinye B. Balogun
- Dezheng Huo
ArticleOpen Access18 Feb 2023 Scientific Reports
Cancer-associated fibroblasts are the main contributors to epithelial-to-mesenchymal signatures in the tumor microenvironment
- Peter M. Szabo
- Amir Vajdi
- Saurabh Saha
ArticleOpen Access21 Feb 2023 Scientific Reports
A model to predict the prognosis of diffuse large B-cell lymphoma based on ultrasound images
- Wenjuan Lu
- Wenqin Chen
- Xinhua Ye
ArticleOpen Access27 Feb 2023 Scientific Reports
Clustering by antigen-presenting genes reveals immune landscapes and predicts response to checkpoint immunotherapy
- Xutong Gong
- Rachel Karchin
ArticleOpen Access18 Jan 2023 Scientific Reports
Predicting EGFR mutational status from pathology images using a real-world dataset
- James J. Pao
- Mikayla Biggs
- Lee A. Albacker
ArticleOpen Access16 Mar 2023 Scientific Reports
Shared hotspot mutations in oncogenes position dogs as an unparalleled comparative model for precision therapeutics
- Lucas Rodrigues
- Joshua Watson
- Shaying Zhao
ArticleOpen Access6 Jul 2023 Scientific Reports
Polypropylene microplastics promote metastatic features in human breast cancer
- Jun Hyung Park
- Seungwoo Hong
- Hyun Jung Lee
ArticleOpen Access17 Apr 2023 Scientific Reports
Absolute dosimetry for FLASH proton pencil beam scanning radiotherapy
- Ana Lourenço
- Anna Subiel
- Russell Thomas
ArticleOpen Access4 Feb 2023 Scientific Reports
Cellular senescence affects energy metabolism, immune infiltration and immunotherapeutic response in hepatocellular carcinoma
- Biao Gao
- Yafei Wang
- Shichun Lu
ArticleOpen Access20 Jan 2023 Scientific Reports
Racial disparities in breast cancer treatment patterns and treatment related adverse events
- Nickolas Stabellini
- Jennifer Cullen
- Alberto J. Montero
ArticleOpen Access22 Jan 2023 Scientific Reports
Fc-competent multispecific PDL-1/TIGIT/LAG-3 antibodies potentiate superior anti-tumor T cell response
- Riyao Yang
- Su Huang
- Yue Liu
ArticleOpen Access18 Jun 2023 Scientific Reports
Anti-inflammatory effect of combining fish oil and evening primrose oil supplementation on breast cancer patients undergoing chemotherapy: a randomized placebo-controlled trial
- Aleksandra Arsic
- Predrag Krstic
- Vesna Vucic
ArticleOpen Access20 Apr 2023 Scientific Reports
Incidence and risk of pancreatic cancer in patients with chronic pancreatitis: defining the optimal subgroup for surveillance
- Hyo Suk Kim
- Tae-Geun Gweon
- Jae Hyuck Chang
ArticleOpen Access3 Jan 2023 Scientific Reports
A 3-month survival model after Gamma Knife surgery in patients with brain metastasis from lung cancer with Karnofsky performance status ≤ 70
- Hangeul Park
- Hyun-Tai Chung
- Eun Jung Lee
ArticleOpen Access12 Aug 2023 Scientific Reports

26-50

A novel facile synthesis of metal nitride@metal oxide (BN/Gd₂O₃) nanocomposite and their antibacterial and anticancer activities
- Mayyadah H. Mohsin
- Khawla S. Khashan
- Ashok Aspatwar
ArticleOpen Access20 Dec 2023 Scientific Reports
Tubule-U-Net: a novel dataset and deep learning-based tubule segmentation framework in whole slide images of breast cancer
- Eren Tekin
- Çisem Yazıcı
- Burak Uzel
ArticleOpen Access4 Jan 2023 Scientific Reports
LINE-1 ORF1p as a candidate biomarker in high grade serous ovarian carcinoma
- Sho Sato
- Michael Gillette
- Ronny Drapkin
ArticleOpen Access27 Jan 2023 Scientific Reports
CAR-tropic extracellular vesicles carry tumor-associated antigens and modulate CAR T cell functionality
- V. M. Ukrainskaya
- O. E. Musatova
- A. G. Gabibov
ArticleOpen Access10 Jan 2023 Scientific Reports
Controlled tumor heterogeneity in a co-culture system by 3D bio-printed tumor-on-chip model
- Nafiseh Moghimi
- Seied Ali Hosseini
- Mohammad Kohandel
ArticleOpen Access22 Aug 2023 Scientific Reports
Incidence trends and spatial distributions of lung adenocarcinoma and squamous cell carcinoma in Taiwan
- Hsin-I Liu
- Chun-Ju Chiang
- Wen-Chung Lee
ArticleOpen Access30 Jan 2023 Scientific Reports
Simultaneous activation of CXC chemokine receptor 4 and histamine receptor H1 enhances calcium signaling and cancer cell migration
- Chulo Park
- Jin-Woo Lee
- Won-Ki Huh
ArticleOpen Access2 Feb 2023 Scientific Reports
Machine learning based combination of multi-omics data for subgroup identification in non-small cell lung cancer
- Seema Khadirnaikar
- Sudhanshu Shukla
- S. R. M. Prasanna
ArticleOpen Access21 Mar 2023 Scientific Reports
Risk factors for the development of triple-negative breast cancer versus non-triple-negative breast cancer: a case–control study
- Shona Nag
- Rajesh Dikshit
- Sudeep Gupta
ArticleOpen Access20 Aug 2023 Scientific Reports
Deep learning for multi-class semantic segmentation enables colorectal cancer detection and classification in digital pathology images
- John-Melle Bokhorst
- Iris D. Nagtegaal
- Francesco Ciompi
ArticleOpen Access24 May 2023 Scientific Reports
Identification of germline cancer predisposition variants in pediatric sarcoma patients from somatic tumor testing
- Piedad Alba-Pavón
- Lide Alaña
- Olatz Villate
ArticleOpen Access20 Feb 2023 Scientific Reports
E-liquid exposure induces bladder cancer cells to release extracellular vesicles that promote non-malignant urothelial cell transformation
- Ryan D. Molony
- Chia-Hao Wu
- Yi-Fen Lee
ArticleOpen Access4 Jan 2023 Scientific Reports
Advances in methylation analysis of liquid biopsy in early cancer detection of colorectal and lung cancer
- Hyuk-Jung Kwon
- Sun Hye Shin
- Min Seob Lee
ArticleOpen Access19 Aug 2023 Scientific Reports
Systematic review of NTRK 1/2/3 fusion prevalence pan-cancer and across solid tumours
- Sophie O’Haire
- Fanny Franchini
- Maarten IJzerman
ArticleOpen Access13 Mar 2023 Scientific Reports
Pneumonitis associated with pembrolizumab plus chemotherapy for non-squamous non-small cell lung cancer
- Daichi Fujimoto
- Satoru Miura
- Nobuyuki Yamamoto
ArticleOpen Access6 Mar 2023 Scientific Reports
Efficient breast cancer mammograms diagnosis using three deep neural networks and term variance
- Ahmed S. Elkorany
- Zeinab F. Elsharkawy
ArticleOpen Access15 Feb 2023 Scientific Reports
Nanosecond pulsed electric field suppresses growth and reduces multi-drug resistance effect in pancreatic cancer
- Wojciech Szlasa
- Olga Michel
- Julita Kulbacka
ArticleOpen Access7 Jan 2023 Scientific Reports
Termination of trastuzumab in HER2-positive metastatic breast cancer patients who received trastuzumab beyond progression
- Izzet Dogan
- Esra Aydin
- Adnan Aydiner
ArticleOpen Access31 May 2023 Scientific Reports
Survival outcomes of patients with metastatic non-small cell lung cancer receiving chemotherapy or immunotherapy as first-line in a real-life setting
- Yaniss Belaroussi
- Fanny Bouteiller
- Sophie Cousin
ArticleOpen Access13 Jun 2023 Scientific Reports
Activated T cell therapy targeting glioblastoma cancer stem cells
- Ken Miyaguchi
- Hongqiang Wang
- John S. Yu
ArticleOpen Access5 Jan 2023 Scientific Reports
Genomic and molecular landscape of homologous recombination deficiency across multiple cancer types
- Zhiwen Shi
- Bolin Chen
- Lin Wu
ArticleOpen Access1 Jun 2023 Scientific Reports
The effect of resveratrol, curcumin and quercetin combination on immuno-suppression of tumor microenvironment for breast tumor-bearing mice
- Chenchen Li
- Yajun Xu
- Yanli Wang
ArticleOpen Access16 Aug 2023 Scientific Reports
Region of interest (ROI) selection using vision transformer for automatic analysis using whole slide images
- Md Shakhawat Hossain
- Galib Muhammad Shahriar
- Suresh Advani
ArticleOpen Access13 Jul 2023 Scientific Reports
Modeling of intracranial tumor treating fields for the treatment of complex high-grade gliomas
- David J. Segar
- Joshua D. Bernstock
- Sumientra M. Rampersad
ArticleOpen Access30 Jan 2023 Scientific Reports
Appropriate screening mammography method for patients with breast implants
- Jihee Park
- Eun Young Ko
- Haejung Kim
ArticleOpen Access1 Feb 2023 Scientific Reports

51-75

Dual blockage of both PD-L1 and CD47 enhances the therapeutic effect of oxaliplatin and FOLFOX in CT-26 mice tumor model
- Reza Alimohammadi
- Ghanbar Mahmoodi Chalbatani
- Seyed Amir Jalali
ArticleOpen Access11 Feb 2023 Scientific Reports
Targeting BAP1 with small compound inhibitor for colon cancer treatment
- Minhwa Kang
- Seul Gi Park
- Jongbum Kwon
ArticleOpen Access8 Feb 2023 Scientific Reports
Machine learning-based approaches for cancer prediction using microbiome data
- Pedro Freitas
- Francisco Silva
- Hélder P. Oliveira
ArticleOpen Access21 Jul 2023 Scientific Reports
Identification of a hypoxia-related gene prognostic signature in colorectal cancer based on bulk and single-cell RNA-seq
- Yihuan Qiao
- Xunliang Jiang
- Jipeng Li
ArticleOpen Access13 Feb 2023 Scientific Reports
Evaluation of automated techniques for extraction of circulating cell-free DNA for implementation in standardized high-throughput workflows
- Sarah Lehle
- Julius Emons
- Hanna Huebner
ArticleOpen Access7 Jan 2023 Scientific Reports
Epigenetic modification of gene expression in cancer cells by terahertz demethylation
- Hwayeong Cheon
- Junho K. Hur
- Joo-Hiuk Son
ArticleOpen Access26 Mar 2023 Scientific Reports
Breast cancer histopathology image-based gene expression prediction using spatial transcriptomics data and deep learning
- Md Mamunur Rahaman
- Ewan K. A. Millar
- Erik Meijering
ArticleOpen Access21 Aug 2023 Scientific Reports
The NK cell checkpoint NKG2A maintains expansion capacity of human NK cells
- Meike Kaulfuss
- Juliane Mietz
- Obinna Chijioke
ArticleOpen Access29 Jun 2023 Scientific Reports
TOR1B: a predictor of bone metastasis in breast cancer patients
- Minh Nam Nguyen
- Salima Akter
- Tae Gyu Choi
ArticleOpen Access27 Jan 2023 Scientific Reports
An integrative machine learning framework for classifying SEER breast cancer
- P. Manikandan
- U. Durga
- C. Ponnuraja
ArticleOpen Access1 Apr 2023 Scientific Reports
Comparative dosimetric analysis of volumetric modulated arc therapy based craniospinal irradiation plans between Halcyon ring gantry and TrueBeam C-arm linear accelerator
- Biplab Sarkar
- Subhra Snigdha Biswal
- Luca Cozzi
ArticleOpen Access1 Mar 2023 Scientific Reports
Detection of oral squamous cell carcinoma in clinical photographs using a vision transformer
- Tabea Flügge
- Robert Gaudin
- Shankeeth Vinayahalingam
ArticleOpen Access9 Feb 2023 Scientific Reports
Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes
- Pamela Ajuyah
- Chelsea Mayoh
- Dong-Anh Khuong-Quang
ArticleOpen Access7 Mar 2023 Scientific Reports
Discovery of rafoxanide as a novel agent for the treatment of non-small cell lung cancer
- Ankang Hu
- Jing Liu
- Tingjun Liu
ArticleOpen Access13 Jan 2023 Scientific Reports
SLC11A2: a promising biomarker and therapeutic target in ovarian cancer
- Liming Tian
- Xuemei Li
- Guofen Yang
ArticleOpen Access20 Jan 2023 Scientific Reports
HX009, a novel BsAb dual targeting PD1 x CD47, demonstrates potent anti-lymphoma activity in preclinical models
- Hang Ke
- Faming Zhang
- Qi-Xiang Li
ArticleOpen Access3 Apr 2023 Scientific Reports
Circulating cf-miRNA as a more appropriate surrogate liquid biopsy marker than cfDNA for ovarian cancer
- Aoife Ward Gahlawat
- Tania Witte
- Sarah Schott
ArticleOpen Access4 Apr 2023 Scientific Reports
Prediction of pathologic complete response to neoadjuvant systemic therapy in triple negative breast cancer using deep learning on multiparametric MRI
- Zijian Zhou
- Beatriz E. Adrada
- Jingfei Ma
ArticleOpen Access20 Jan 2023 Scientific Reports
Plasma proteome of growing tumors
- Shashi Gupta
- Matthew J. Westacott
- Nebojsa Janjic
ArticleOpen Access27 Jul 2023 Scientific Reports
High-throughput isolation of cancer cells in spiral microchannel by changing the direction, magnitude and location of the maximum velocity
- Vahid Omrani
- Mohammad Zabetian Targhi
- Reza Nosrati
ArticleOpen Access24 Feb 2023 Scientific Reports
Engineered E. coli Nissle 1917 for delivery of bioactive IL-2 for cancer immunotherapy
- Sarunas Tumas
- Trine Sundebo Meldgaard
- Morten O. A. Sommer
ArticleOpen Access2 Aug 2023 Scientific Reports
Identifying molecular targets of Aspiletrein-derived steroidal saponins in lung cancer using network pharmacology and molecular docking-based assessments
- Iksen Iksen
- Wasita Witayateeraporn
- Varisa Pongrakhananon
ArticleOpen Access27 Jan 2023 Scientific Reports
Antiproliferative effects of mitochondria-targeted N-acetylcysteine and analogs in cancer cells
- Gang Cheng
- Micael Hardy
- Balaraman Kalyanaraman
ArticleOpen Access4 May 2023 Scientific Reports
Epigenetic alterations impede epithelial-mesenchymal transition by modulating centrosome amplification and Myc/RAS axis in triple negative breast cancer cells
- Laxmidhar Das
ArticleOpen Access11 Feb 2023 Scientific Reports
Targeting mTOR to overcome resistance to hormone and CDK4/6 inhibitors in ER-positive breast cancer models
- María Jimena Rodriguez
- María Cecilia Perrone
- Virginia Novaro
ArticleOpen Access15 Feb 2023 Scientific Reports

76-100

Four-year follow-up on fatigue and sleep quality of a three-armed partly randomized controlled study in breast cancer survivors with cancer-related fatigue
- M. Kröz
- F. Quittel
- the CRF study group
ArticleOpen Access15 Feb 2023 Scientific Reports
GPX4 overexpressed non-small cell lung cancer cells are sensitive to RSL3-induced ferroptosis
- Joo-Won Kim
- Dong Wha Min
- Ji-Yun Lee
ArticleOpen Access31 May 2023 Scientific Reports
Genetic determinants and absence of breast cancer in Xavante Indians in Sangradouro Reserve, Brazil
- Yan Zhou
- Jose Russo
- Guilherme Bezerra de Castro
ArticleOpen Access26 Jan 2023 Scientific Reports
Pediatric T-cell acute lymphoblastic leukemia blast signature and MRD associated immune environment changes defined by single cell transcriptomics analysis
- Swati S. Bhasin
- Beena E. Thomas
- Deborah DeRyckere
ArticleOpen Access2 Aug 2023 Scientific Reports
Long-term use of denosumab and its association with skeletal-related events and osteonecrosis of the jaw
- Pei-An Fu
- Chin-Yao Shen
- Wei-Pang Chung
ArticleOpen Access24 May 2023 Scientific Reports
A novel 3D culture model for human primary mammary adipocytes to study their metabolic crosstalk with breast cancer in lean and obese conditions
- Marie Rebeaud
- Caroline Bouche
- Catherine Muller
ArticleOpen Access22 Mar 2023 Scientific Reports
Network pharmacology analysis reveals potential targets and mechanisms of proton pump inhibitors in breast cancer with diabetes
- Haihong Hu
- Hanbin Wang
- Taolan Zhang
ArticleOpen Access10 May 2023 Scientific Reports
Prediction of breast cancer using blood microbiome and identification of foods for breast cancer prevention
- Jeongshin An
- Jinho Yang
- Byung-In Moon
ArticleOpen Access29 Mar 2023 Scientific Reports
Improving the robustness and stability of a machine learning model for breast cancer prognosis through the use of multi-modal classifiers
- Nikhilanand Arya
- Sriparna Saha
- Snehanshu Saha
ArticleOpen Access11 Mar 2023 Scientific Reports
Biogenic copper oxide nanoparticles from Bacillus coagulans induced reactive oxygen species generation and apoptotic and anti-metastatic activities in breast cancer cells
- Masoumeh Dolati
- Farzaneh Tafvizi
- Parvaneh Jafari
ArticleOpen Access24 Feb 2023 Scientific Reports
Effects of the exercise-inducible myokine irisin on proliferation and malignant properties of ovarian cancer cells through the HIF-1 α signaling pathway
- Marziyeh Alizadeh Zarei
- Elahe Seyed Hosseini
- Hossein Nikzad
ArticleOpen Access4 Jan 2023 Scientific Reports
Potential of bacteriophage therapy in managing Staphylococcus aureus infections during chemotherapy for lung cancer patients
- Jiaqi Li
- Huangliang Zheng
- Sharon Shui Yee Leung
ArticleOpen Access12 Jun 2023 Scientific Reports
Diagnostic ability of deep learning in detection of pancreatic tumour
- M. G. Dinesh
- Nebojsa Bacanin
- Mohamed Abouhawwash
ArticleOpen Access15 Jun 2023 Scientific Reports
Artificial intelligence-based radiomics for the prediction of nodal metastasis in early-stage lung cancer
- Yoshihisa Shimada
- Yujin Kudo
- Norihiko Ikeda
ArticleOpen Access19 Jan 2023 Scientific Reports
CDCP1 expression is frequently increased in aggressive urothelial carcinoma and promotes urothelial tumor progression
- Miriam Saponaro
- Sina Flottmann
- Abdullah Alajati
ArticleOpen Access2 Jan 2023 Scientific Reports
Nrf2 inhibition increases sensitivity to chemotherapy of colorectal cancer by promoting ferroptosis and pyroptosis
- Yongzhou Huang
- Wenchang Yang
- Kaixiong Tao
ArticleOpen Access1 Sep 2023 Scientific Reports
Identification of TP53 mutations in circulating tumour DNA in high grade serous ovarian carcinoma using next generation sequencing technologies
- Leslie Calapre
- Tindaro Giardina
- Elin S. Gray
ArticleOpen Access6 Jan 2023 Scientific Reports
A comprehensive analysis of PANoptosome to prognosis and immunotherapy response in pan-cancer
- Lingling Zhuang
- Qiran Sun
- Qi Chen
ArticleOpen Access8 Mar 2023 Scientific Reports
Meta-analysis of laparoscopic radical hysterectomy, excluding robotic assisted versus open radical hysterectomy for early stage cervical cancer
- Greg Marchand
- Ahmed Taher Masoud
- Malini Govindan
ArticleOpen Access6 Jan 2023 Scientific Reports
Prognostic impact of PD-L1 and TIGIT expression in non-small cell lung cancer following concurrent chemo-radiotherapy
- Masataka Mori
- Masatoshi Kanayama
- Fumihiro Tanaka
ArticleOpen Access25 Feb 2023 Scientific Reports
High dose of dexamethasone attenuates docetaxel-induced fluid retention in breast cancer treatment
- Yoshitaka Saito
- Ryota Kanno
- Mitsuru Sugawara
ArticleOpen Access7 Jun 2023 Scientific Reports
Cytotoxic and chemomodulatory effects of Phyllanthus niruri in MCF-7 and MCF-7^ADR breast cancer cells
- Ola E. Abdel-Sattar
- Rasha Mosa Allam
- Meselhy R. Meselhy
ArticleOpen Access15 Feb 2023 Scientific Reports
Automatic detection of circulating tumor cells and cancer associated fibroblasts using deep learning
- Cheng Shen
- Siddarth Rawal
- Changhuei Yang
ArticleOpen Access7 Apr 2023 Scientific Reports
Transcriptional activity mediated by β-CATENIN and TCF/LEF family members is completely dispensable for survival and propagation of multiple human colorectal cancer cell lines
- Janna Fröhlich
- Katja Rose
- Andreas Hecht
ArticleOpen Access6 Jan 2023 Scientific Reports
Rewiring of the 3D genome during acquisition of carboplatin resistance in a triple-negative breast cancer patient-derived xenograft
- Mikhail G. Dozmorov
- Maggie A. Marshall
- J. Chuck Harrell
ArticleOpen Access3 Apr 2023 Scientific Reports

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