Collection 

Time-resolved structure determination

Submission status
Closed
Submission deadline

Time-resolved structure determination involves a range of techniques to capture and analyze the dynamic structural changes of molecules or materials over time. Methods include X-ray solution scattering and crystallography for the collection of rapid diffraction data during a (chemical) reaction or process; time-resolved spectroscopy for the monitoring of changes in light absorption, emission, or scattering; and ultrafast as well cryo electron microscopy for the capture of structural changes of proteins. Information about time-resolved structure has uses in fields as diverse as chemistry, materials science, and biology, and provide insights into reaction mechanisms, material behavior, and protein folding. New technology, much of it related to advances in computational hardware, is helping to improve time-resolved structure determination and contributing to research in these areas.

This Collection invites the submission of original research that either uses time-resolved structure determination as a main method of the study to address a research question or contributes to the development of methods used during ultra-fast structure determination.

Toll-like receptor 4 (TLR4, extracellular domain) bound to lipopolysaccharide (LPS) and MD-2. Involved in activating the innate immune system upon detecting LPS, a component of many gram-negative bacteria. 3D rendering based on protein data bank entry 3fxi. Combined cartoon and stick representation with backbone gradient coloring. Background black.

Editors

Submitting a paper for consideration

 

To submit your manuscript for consideration at Scientific Reports as part of this Collection, please follow the steps detailed on this page. On the first page of our online submission system, under “I’m submitting:” select the option “any other article type”. Once logged in you can submit your manuscript to a Collection by selecting “Guest Edited Collection”, under the “Choose the appropriate manuscript type” message, and clicking “Continue”. Then when filling out the manuscript information, select the "Time-resolved structure determination" Collection from the alphabetical list on the “Springer Nature Subject Category” tab. Authors should express their interest in the Collection in their cover letter.

Accepted papers are published on a rolling basis as soon as they are ready.

In addition to papers on Time-resolved structure determination, Scientific Reports welcomes all original research in the field of Medical Research. To browse our latest articles in Structral Biology Research click here.

 

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