Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Time-resolved structure determination involves a range of techniques to capture and analyze the dynamic structural changes of molecules or materials over time. Methods include X-ray solution scattering and crystallography for the collection of rapid diffraction data during a (chemical) reaction or process; time-resolved spectroscopy for the monitoring of changes in light absorption, emission, or scattering; and ultrafast as well cryo electron microscopy for the capture of structural changes of proteins. Information about time-resolved structure has uses in fields as diverse as chemistry, materials science, and biology, and provide insights into reaction mechanisms, material behavior, and protein folding. New technology, much of it related to advances in computational hardware, is helping to improve time-resolved structure determination and contributing to research in these areas.
This Collection invites the submission of original research that either uses time-resolved structure determination as a main method of the study to address a research question or contributes to the development of methods used during ultra-fast structure determination.