●Nature Insight on Malaria Nature 7 February (2001) A collection of reviews on malaria; including: Progress and challenges for malaria vaccines. Richie, T. L. & Saul, A. | The pathogenic basis of malaria. Miller, L. H., Baruch, D. I., Marsh, K. & Doumbo, O. K. | Medical need, scientific opportunity and the drive for antimalarial drugs. Ridley, R. G.

●Mucosal gatekeepers: selecting HIV viruses for early infection. Bomsel, M. & David, V. Nature Medicine February (2002) A News and Views article that describes how the first cells encountered by HIV-1 mucosal epithelial cells are not themselves infected, but instead act to selectively transport the R5 virus subtype to CD4+T cells from where the infection spreads.

●Multiple myeloma: evolving genetic events and host interactions. Kuehl, W. M. & Bergsagel, P. L. Nature Reviews Cancer March (2002)

●Effector BCRs: inside information on IgG. Manser, T. Nature Immunology February (2002) This News and Views article discusses a recent study showing that B-cell receptors selectively enhance the proliferation and immunoglobulin production of B cells that express surface IgG.

●Historical insight: whatever happened to cell-bound antibodies? On the overriding influence of dogma. Silverstein, A. M. Nature Immunology February (2002)

●New avenues for anti-inflammatory therapy. Mackay, C. R. Nature Medicine February (2002) This News and Views article discusses recent work showing that the chemokine CCL27 and its receptor CCR10 are key homing molecules for T-cell migration to the skin. Neutralization of CCL27–CCR10 interactions suppresses skin inflammatory responses, and so CCR10 might be a good target for therapy of human skin diseases.

●Innate immunity: the missing link in neuroprotection and neurodegeneration? Nguyen, M. D., Julien, J.-P. & Rivest, S. Nature Reviews Neuroscience March (2002) This review discusses how innate immune responses that occur in the central nervous system can result in protection of neurons, as well as being a direct cause of neurodegeneration.