Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • NEWS

Transplant success reignites interest in reprogramming cells against HIV

T cells infected with HIV. Comstock/Stockbyte/Getty

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

doi: https://doi.org/10.1038/d41591-019-00011-y

**An earlier version of this story included a quote that mischaracterized the status of a clinical study. The article had stated: There were concerns that CSL Behring was keen to drop Calimmune’s HIV work, even though the clinical trial was at an advanced stage. Those fears proved well-founded. “Calimmune has been acquired and is no longer pursuing this study, which has been terminated,” says Ronald Mitsuyasu, a professor of medicine in hematology–oncology at the University of California, Los Angeles, who was the principal investigator on the clinical trial. The phase 1/2 study was actually completed. The agent did not move into a phase 3 trial; however, CSL Behring is funding an additional external study that might be able to demonstrate efficacy. The story has been updated for accuracy.

References

  1. Gupta, R. K. et al. Nature https://doi.org/10.1038/s41586-019-1027-4 (2019).

  2. Samson, M. et al. Nature 382, 722–755 (1996).

    Article  PubMed  Google Scholar 

  3. Liu, R. et al. Cell 86, 367–377 (1996).

  4. Schoofs, M. A doctor, a mutation and a potential cure for AIDS. The Wall Street Journal (2008).

  5. Hütter, G. et al. N. Engl. J. Med. 360, 692–698 (2009).

    Article  PubMed  Google Scholar 

  6. Tebas, P. N. Engl. J. Med. 370, 901–910 (2014).

    Article  PubMed  Google Scholar 

  7. Xu, L. et al. Mol. Ther. 25, 1782–1789 (2017).

    Article  PubMed  Google Scholar 

  8. Kordelas, L. et al. N. Engl. J. Med. 371, 880–882 (2014).

    Article  PubMed  Google Scholar 

  9. Yu, S. Hum. Gene Ther. 29, 51–67 (2018).

    Article  PubMed  Google Scholar 

Download references

Subjects

Latest on:

Nature Careers

Jobs

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing

Search

Quick links