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Virology is the scientific discipline concerned with the study of the biology of viruses and viral diseases, including the distribution, biochemistry, physiology, molecular biology, ecology, evolution and clinical aspects of viruses.
A trial that took mobile health services to rural Sierra Leone finds that this initiative increased COVID-19 vaccine uptake. But more must be done to expand the coverage of health services in low-income countries.
The 1964 discovery of Epstein–Barr virus shed light on factors that contribute to human cancer. Subsequent studies set the stage for finding ways to diagnose and treat cancer, and revealed how immune defences control viral infection.
Human norovirus infection is a major global health concern, but a suitable animal model is lacking. We have established repeated infection with human norovirus in rhesus macaques via oral challenge. Animals demonstrate virus shedding in the stool and subsequent serum antibody responses, and virus replication is detected in the small intestine.
Omicron variants BQ.1.1 and XBB increased pathogenicity in wild-type hamsters, with BQ.1.1 showing higher mortality in human ACE2 transgenic hamsters compared to earlier Omicron variants..
COVID-19 vaccination has been recommended for children and young people (aged 5–17) in the UK since 2021/2022. In this study, the authors use linked health and administrative data to estimate vaccine uptake in this age group and show that age and adult household vaccination status are associated with uptake.
There is limited data on immune factors contributing to SARS-CoV-2 viral clearance in people living with HIV. Here, the authors show that re-emergence of the neutralizing antibody response may be key to clearing persistent SARS-CoV-2 infection in ART-mediated recovery from immunosuppression in advanced HIV disease.
In this Review, de Souza and Weaver discuss the potential effects on vector-borne diseases of climate change, weather and other anthropogenic factors, including land use, human mobility and behaviour, as possible contributors to the redistribution of vectors and spread of vector-borne diseases worldwide.
A trial that took mobile health services to rural Sierra Leone finds that this initiative increased COVID-19 vaccine uptake. But more must be done to expand the coverage of health services in low-income countries.
The 1964 discovery of Epstein–Barr virus shed light on factors that contribute to human cancer. Subsequent studies set the stage for finding ways to diagnose and treat cancer, and revealed how immune defences control viral infection.
In this study, Armani-Tourret et al. show that the combination of panobinostat and pegylated interferon-α2a transforms the structure and composition of the HIV-1 reservoir and could potentially counter it.