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‘Astonishing’ molecular syringe ferries proteins into human cells

Technique borrowed from nature, and honed using artificial intelligence, could spur the development of better drug-delivery systems.
  1. Heidi Ledford
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Researchers have hijacked a molecular ‘syringe’ that some viruses and bacteria use to infect their hosts, and put it to work delivering potentially therapeutic proteins into human cells grown in the laboratory.

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Nature 616, 18-19 (2023)

doi: https://doi.org/10.1038/d41586-023-00922-4

References

  1. Kreitz, J. et al. Nature https://doi.org/10.1038/s41586-023-05870-7 (2023).

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  2. Jiang, F. et al. Sci. Adv. 8, eabm2343 (2022).

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