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| Open AccessPromoting crystallization of intrinsic membrane proteins with conjugated micelles
- Thien Van Truong
- , Mihir Ghosh
- & Guy Patchornik
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| Open AccessDesign of thienopyranone-based BET inhibitors that bind multiple synthetic lethality targets
- Kendra R. Vann
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| Open AccessThe discovery of a new antibody for BRIL-fused GPCR structure determination
- Hikaru Miyagi
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| Open AccessStructural basis of SALM3 dimerization and synaptic adhesion complex formation with PTPσ
- Sudeep Karki
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| Open AccessDiB-splits: nature-guided design of a novel fluorescent labeling split system
- Nina G. Bozhanova
- , Alexey S. Gavrikov
- & Jens Meiler
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| Open AccessAlternative catalytic residues in the active site of Esco acetyltransferases
- Tahereh Ajam
- , Inessa De
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| Open AccessS92 phosphorylation induces structural changes in the N-terminus domain of human mitochondrial calcium uniporter
- Youngjin Lee
- , Jongseo Park
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| Open AccessA disulfide constrains the ToxR periplasmic domain structure, altering its interactions with ToxS and bile-salts
- Charles R. Midgett
- , Rachel A. Swindell
- & F. Jon Kull
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| Open AccessAspartate/asparagine-β-hydroxylase: a high-throughput mass spectrometric assay for discovery of small molecule inhibitors
- Lennart Brewitz
- , Anthony Tumber
- & Christopher J. Schofield
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| Open AccessCrystal structure of Type IX secretion system
PorE C-terminal domain from Porphyromonas gingivalis in complex with a peptidoglycan fragment- Nhung Thi Trang Trinh
- , Hieu Quang Tran
- & Philippe Leone
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| Open AccessStructure-based engineering of anti-GFP nanobody tandems as ultra-high-affinity reagents for purification
- Ziyue Zhang
- , Yao Wang
- & Motoyuki Hattori
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| Open AccessMolecular mechanism of the dual regulatory roles of ATP on the αγ heterodimer of human NAD-dependent isocitrate dehydrogenase
- Pengkai Sun
- , Tuya Bai
- & Jianping Ding
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| Open AccessStructural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the α-d-phosphohexomutase superfamily
- Paul Hoff Backe
- , Jon K. Laerdahl
- & Magnar Bjørås
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| Open AccessCrystal structure of pathogenic Staphylococcus aureus lipase complex with the anti-obesity drug orlistat
- Kengo Kitadokoro
- , Mutsumi Tanaka
- & Shigeki Kamitani
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| Open AccessX-ray Crystallography and Electron Paramagnetic Resonance Spectroscopy Reveal Active Site Rearrangement of Cold-Adapted Inorganic Pyrophosphatase
- Masaki Horitani
- , Kazuki Kusubayashi
- & Keiichi Watanabe
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| Open AccessDistinct surfaces on Cdc5/PLK Polo-box domain orchestrate combinatorial substrate recognition during cell division
- Ahmad W. Almawi
- , Laurence Langlois-Lemay
- & Alba Guarné
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| Open AccessAedes aegypti Odorant Binding Protein 22 selectively binds fatty acids through a conformational change in its C-terminal tail
- Jing Wang
- , Emma J. Murphy
- & David N. M. Jones
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| Open AccessStructural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine
- Yoshiaki Yasutake
- , Shin-ichiro Hattori
- & Hiroaki Mitsuya
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| Open AccessWhat does fluorine do to a protein? Thermodynamic, and highly-resolved structural insights into fluorine-labelled variants of the cold shock protein
- Hannah Welte
- , Tiankun Zhou
- & Michael Kovermann
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| Open AccessComparative study of the interactions between fungal transcription factor nuclear localization sequences with mammalian and fungal importin-alpha
- Natália E. Bernardes
- , Cintia A. Fukuda
- & Marcos R. M. Fontes
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| Open AccessViscosity-adjustable grease matrices for serial nanocrystallography
- Michihiro Sugahara
- , Koji Motomura
- & Tetsuya Ishikawa
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| Open AccessStructural characterization and in-silico analysis of Momordica charantia 7S globulin for stability and ACE inhibition
- Pooja Kesari
- , Shivendra Pratap
- & Pravindra Kumar
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| Open AccessConformational changes in Apolipoprotein N-acyltransferase (Lnt)
- Benjamin Wiseman
- & Martin Högbom
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| Open AccessStructural insights into the promiscuous DNA binding and broad substrate selectivity of fowlpox virus resolvase
- Na Li
- , Ke Shi
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| Open AccessStructural analysis of mycobacterial homoserine transacetylases central to methionine biosynthesis reveals druggable active site
- Catherine T. Chaton
- , Emily S. Rodriguez
- & Konstantin V. Korotkov
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| Open AccessBiochemical and structural insights into the cytochrome P450 reductase from Candida tropicalis
- Ana C. Ebrecht
- , Naadia van der Bergh
- & Diederik J. Opperman
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| Open AccessHigh resolution structural and functional analysis of a hemopexin motif protein from Dolichos
- Sarita Chandan Sharma
- , Ashish Kumar
- & Dinakar M. Salunke
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| Open AccessStructural basis of methotrexate and pemetrexed action on serine hydroxymethyltransferases revealed using plant models
- Milosz Ruszkowski
- , Bartosz Sekula
- & Zbigniew Dauter
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| Open AccessClustering of atomic displacement parameters in bovine trypsin reveals a distributed lattice of atoms with shared chemical properties
- Viktor Ahlberg Gagnér
- , Ida Lundholm
- & Gergely Katona
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| Open AccessThe CC′ loop of IgV domains of the immune checkpoint receptors, plays a key role in receptor:ligand affinity modulation
- Shankar V. Kundapura
- & Udupi A. Ramagopal
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| Open AccessThe unique structural features of carbonmonoxy hemoglobin from the sub-Antarctic fish Eleginops maclovinus
- Nicole Balasco
- , Luigi Vitagliano
- & Alessandro Vergara
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| Open AccessUnusual features of the c-ring of F1FO ATP synthases
- A. V. Vlasov
- , K. V. Kovalev
- & V. I. Gordeliy
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| Open AccessHow water-mediated hydrogen bonds affect chlorophyll a/b selectivity in Water-Soluble Chlorophyll Protein
- Alessandro Agostini
- , Elena Meneghin
- & Elisabetta Collini
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| Open AccessMolecular and structural insights into an asymmetric proteolytic complex (ClpP1P2) from Mycobacterium smegmatis
- Jyotsna Nagpal
- , Jason J. Paxman
- & David A. Dougan
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| Open AccessStructural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920)
- Guilherme H. M. Salvador
- , Antoniel A. S. Gomes
- & Marcos R. M. Fontes
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| Open AccessMycobacterium tuberculosis CysA2 is a dual sulfurtransferase with activity against thiosulfate and 3-mercaptopyruvate and interacts with mammalian cells
- A. N. Meza
- , C. C. N. Cambui
- & A. Balan
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| Open AccessStructures of GapR reveal a central channel which could accommodate B-DNA
- Michael J. Tarry
- , Christoph Harmel
- & T. Martin Schmeing
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| Open AccessCrystal structure of suboptimal viral fragments of Epstein Barr Virus Rta peptide-HLA complex that stimulate CD8 T cell response
- Xuelu Huan
- , Ziyi Zhuo
- & Ee Chee Ren
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| Open AccessA host dTMP-bound structure of T4 phage dCMP hydroxymethylase mutant using an X-ray free electron laser
- Si Hoon Park
- , Jaehyun Park
- & Hyun Kyu Song
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| Open AccessRigid fusions of designed helical repeat binding proteins efficiently protect a binding surface from crystal contacts
- Patrick Ernst
- , Annemarie Honegger
- & Andreas Plückthun
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| Open AccessStructural and thermodynamic basis for the recognition of the substrate-binding cleft on hen egg lysozyme by a single-domain antibody
- Hiroki Akiba
- , Hiroko Tamura
- & Kouhei Tsumoto
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| Open AccessMacrophage migration inhibitory factor of Syrian golden hamster shares structural and functional similarity with human counterpart and promotes pancreatic cancer
- Voddu Suresh
- , Rajivgandhi Sundaram
- & Shantibhusan Senapati
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| Open AccessCrystal structure of the catalytic unit of GH 87-type α-1,3-glucanase Agl-KA from Bacillus circulans
- Shigekazu Yano
- , Wasana Suyotha
- & Koki Makabe
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| Open AccessStructural analysis of biological targets by host:guest crystal lattice engineering
- Patrick Ernst
- , Andreas Plückthun
- & Peer R. E. Mittl
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| Open AccessFucosylated inhibitors of recently identified bangle lectin from Photorhabdus asymbiotica
- Gita Paulíková
- , Josef Houser
- & Michaela Wimmerová
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Article
| Open AccessStructural and biochemical characterisation of a novel alginate lyase from Paenibacillus sp. str. FPU-7
- Takafumi Itoh
- , Emi Nakagawa
- & Hisashi Kimoto
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| Open AccessSwitch of the interactions between the ribosomal stalk and EF1A in the GTP- and GDP-bound conformations
- Kei Maruyama
- , Hirotatsu Imai
- & Toshio Uchiumi
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| Open AccessThe C-terminal region of human plasma fetuin-B is dispensable for the raised-elephant-trunk mechanism of inhibition of astacin metallopeptidases
- Tibisay Guevara
- , Hagen Körschgen
- & F. Xavier Gomis-Rüth